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I did read all of the cautions, including my Doctors caution to take Niaspan at night. But I took one 500 mg tablet as soon as I picked it up at the pharmacy. Nothing happened until six hours later when I got the tingling, itching Niacin flush in my face and neck for about 30 minutes. Just to throw caution to the wind, I took another two 500 mg tablets at bedtime. No effects that I can recall, so maybe my Doctor is correct. Take the Niaspan at night and you won't know if you had side-effects. I take 2000 mg. Slo Niacin from Costco, divided into morning and evening doses, and rarely have flushing. I've noticed that the flushing is worse if I drink alcohol, and can be aleviated somewhat if I take aspirin with the niacin. I take 81 mg aspirin every evening with my niacin, so that probably helps eliminate the effect of wine or beer with

dinner. If I stop the niacin for a while and restart, I tend to experience a bit of flushing again. I take 20 mg Lipitor and 145 mg Tricor, as well as 4000 mg. fish oil capsules and 2000 mg. acetyl l-carnitine. Lipid numbers have been good, but liver enzymes somewhat elevated. I'm going to go over everything I'm taking with my doctor at my next visit to see whether I should consider reducing or eliminating anything I'm taking.

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