psoriasis / severe rash

[Guest guest]

Maurine wrote:

anyone have info or a link to flu vaccine and psoriasis for a friend who

started to get it 5 years ago when she began getting flu vaccines every year.

Also need to know what med(not mainstream) is used for it. She has it really

bad.

TIA, maurine

Here are some links your friend may find of interest:

A new cutaneous sign of mercury poisoning?

Dantzig PI.

J Am Acad Dermatol. 2003 Dec;49(6):1109-11.

Trends in incidence of adult-onset psoriasis over three decades: A ...

CONCLUSION: The annual incidence of psoriasis almost doubled between the 1970s

and 2000. The reasons for this increase in incidence are currently unknown, ...

linkinghub.elsevier.com/retrieve/pii/S0190962208014564 - Similar pages -

by M Icen - 2008

The role of mercury in pustulosis palmaris et plantaris

Journal of Occupational and Environmental Medicine - Volume 45, Issue 5 (May

2003) - Copyright © 2003 American College of Occupational and Environmental

Medicine - About This Journal

Letters to the Editor

Br Med J. 1956 Nov 24;2(5003):1202-6. Links

Mercury absorption and psoriasis.

GORDON B, INMAN PM, TRINDER P.

PMID: 13364416 [PubMed - indexed for MEDLINE]

Hautarzt. 1994 Oct;45(10):708-10.Links

[Exacerbation of pustular psoriasis in mercury poisoning]

Arch Dermatol. 1991 Sep;127(9):1333-8.Links

Acute generalized exanthematous pustulosis. Analysis of 63 cases.

Roujeau JC, Bioulac-Sage P, Bourseau C, Guillaume JC, Bernard P, Lok C, Plantin

P, Claudy A, Delavierre C, Vaillant L, et al.

Department of Dermatology, University of CrŽteil, France.

We retrospectively analyzed 63 observations collected in nine French departments

of dermatology of an acute pustular dermatosis, recently named in the French

literature acute generalized exanthematous pustulosis (AGEP). Even though 11 of

these cases occurred in patients with a history of psoriasis, AGEP appeared

distinct from pustular psoriasis based on several slight pathologic differences,

drug induction in most cases, and a more acute course of fever and pustulosis,

with rapid spontaneous healing. We, therefore, suggest that AGEP is a reaction

pattern, perhaps favored by a " psoriatic background. " The most frequent causes

of AGEP seem to be drug reactions, acute infections with enteroviruses,**** and

hypersensitivity to mercury.***** With 55 (87%) of 63 cases attributed to drugs

in this series, AGEP should be added to the list of cutaneous adverse drug

reactions. Among drug-induced skin eruptions, AGEP is remarkable by its short

time to onset after the administration of the suspected drug (less than 24 hours

in half of our cases) and the great predominance (80%) of antibiotics as

causative agents. It is suggested that some cases previously reported as

" drug-induced pustular psoriasis " were in fact AGEP.

Good info here also:

http://www.flcv.com/inflamhg.html

Also Dantzig used to have an unpublished paper posted on the web discussing

guttate psoriasis caused by mercury, but I couldn't find that. He reported that

patients improved using chelation therapy.

From firsthand observation I can report that low dose dmsa rounds per Cutler's

protocol seemed to result in the disappearance of an extensive and severe

psoriasis rash (on a child). The rash (diagnosed as psoriasis) had not seemed to

respond much at all to the creams or limited sunlight exposure prescribed by the

diagnosing dermatologist, but showed significant improvement after just one day

of a Cutler-style dmsa round.

Good luck to your friend.

Sue