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Re: 5-HTP

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I've been on St. 's Wort for about three years. I've experienced

no sexual side-effects at all, as opposed to ssris. However, it

completely damaged my hearing (I just posted a message on that topic).

So before taking St. 's Wort, I suggest you read the message.

>

> > does 5-HTP creates the same kind of sexual dysfunction ?

> > seems like 5-HTP is an excellent SSRI replacement, natural and lower

> > side-effects.

> >

> > comments ?

>

> I wouldn't expect it to have similar side effects because the mode of

> aciton is completly different than SSRIs.

>

> SSRIs " work " by making neurons release serotonin more rapidly so as to

> increase the effective concentration of serotonin without there

actually

> being anymore of the stuff. The various SSRIs are systemic drugs... it

> is known that they cause this effect, but the details of how they do so

> is variable and not generally understood. Note, this is not " about "

> whether it's " natural " or not... the herb St. 's Wort used by many

> folks for depression is an SSRI as certainly as Prozac is.

>

> 5-HTP is a much more targeted drug, in that it isn't generally

systemic.

> Furthermore, it has a " gentler " mode of action since it works with

> your body's biochemistry. Basically, it is a precursor to serotonin

> (and melatonin and other neurological chemicals). It crosses the

> blood/brain barrier, and thereby provides more of the stuff your body

> uses to make serotonin. But when taken in reasonable dosages, it's not

> going to increase effective serontinin levels more than your brain

> decides it needs. It has built in " brakes " that SSRIs do not have.

>

> I would not expect anything like the same level of side effects as from

> SSRIs since 5-HTP works within your own biochemistry rather than

> " forcing " a change. Of course, overdoing 5-HTP *would* force a

change -

> just cause it's natural doesn't mean it can't be abused.

>

> The " problem " with 5-HTP is because it's an herbal extract, it

cannot be

> patented, so no drug company has the motivation to spend the

millions it

> takes to get FDA approval. This is the downside of all " natural "

> medications. You pretty much have to depend on basic research as there

> just isn't any formal drug-related research for natural medicines.

>

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Never heard of the side effect. It is possible it could be related to other factor?On 5/24/06, teephos <teephos@...

> wrote:

I've been on St. 's Wort for about three years. I've experienced

no sexual side-effects at all, as opposed to ssris. However, it

completely damaged my hearing (I just posted a message on that topic).

So before taking St. 's Wort, I suggest you read the message.

>

> > does 5-HTP creates the same kind of sexual dysfunction ?

> > seems like 5-HTP is an excellent SSRI replacement, natural and lower

> > side-effects.

> >

> > comments ?

>

> I wouldn't expect it to have similar side effects because the mode of

> aciton is completly different than SSRIs.

>

> SSRIs " work " by making neurons release serotonin more rapidly so as to

> increase the effective concentration of serotonin without there

actually

> being anymore of the stuff. The various SSRIs are systemic drugs... it

> is known that they cause this effect, but the details of how they do so

> is variable and not generally understood. Note, this is not " about "

> whether it's " natural " or not... the herb St. 's Wort used by many

> folks for depression is an SSRI as certainly as Prozac is.

>

> 5-HTP is a much more targeted drug, in that it isn't generally

systemic.

> Furthermore, it has a " gentler " mode of action since it works with

> your body's biochemistry. Basically, it is a precursor to serotonin

> (and melatonin and other neurological chemicals). It crosses the

> blood/brain barrier, and thereby provides more of the stuff your body

> uses to make serotonin. But when taken in reasonable dosages, it's not

> going to increase effective serontinin levels more than your brain

> decides it needs. It has built in " brakes " that SSRIs do not have.

>

> I would not expect anything like the same level of side effects as from

> SSRIs since 5-HTP works within your own biochemistry rather than

> " forcing " a change. Of course, overdoing 5-HTP *would* force a

change -

> just cause it's natural doesn't mean it can't be abused.

>

> The " problem " with 5-HTP is because it's an herbal extract, it

cannot be

> patented, so no drug company has the motivation to spend the

millions it

> takes to get FDA approval. This is the downside of all " natural "

> medications. You pretty much have to depend on basic research as there

> just isn't any formal drug-related research for natural medicines.

>

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In my case, absolutely no. I'd bet my life on that. Apart from

screwing up my hearing, St. 's Wort was decent (few side-effects)

It's not very potent, though. I only got tinnitus after increasing the

dosage (3x2 Jarsin 300). If you're interested, give it a try, but be

sure to take action if you get tinnitus (even if it's volume is very

low).

> >

> > I've been on St. 's Wort for about three years. I've experienced

> > no sexual side-effects at all, as opposed to ssris. However, it

> > completely damaged my hearing (I just posted a message on that topic).

> > So before taking St. 's Wort, I suggest you read the message.

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