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Re: Question on BP meds in General

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thanks for the info Pierre. No I have not ever been on a beta

blocker. I went to the Doctor today and they told me my 24 hour

Protein was only 300mg. I often notice pretty heavy foam in my urine

so I am confused as to how it is this low? I guess you can't judge

it that way. Is there anything else that might cause Foamy Urine?

Anyway my creatine was 1.9 and my creatine clearance 55. My blood

pressure was high at 160/95. So the Doc. Increased my CLonidine

to .2mg 4 times a day.

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You can't really tell how much proteinuria there is by the presence of foam

in the urine. Even mild proteinuria will produce foam. In terms of other

disorders, I believe there are some liver conditions that can cause foamy

urine as well, but I really don't know much about that.

300 mg/d of proteinuria is pretty mild in the grand scheme of things. Most

of the evidence that lowering proteinuria with any of the 3 classes of BP

meds that have that effect seems to indicate that there isn't much benefit

anyway if the proteinuria is mild like that. The main thing, in my opinion,

is to get the blood pressure quite a bit lower than that, aiming for 120/80

or thereabouts - that will probably protect your kidneys in the long run

more than anything else you can do. It's great if you can tolerate

clonidine, because most people don't tolerate it very well. I'm sure your

doctor has his reasons, but I find it puzzling that clonidine would be used

before ACE inhibitors, beta blockers and angiotensin II receptor blockers

have been tried in a patient with mild IgAN.

You seem to be about where I was in the late 80's and early 90's - mild IgAN

but BP that is relatively high for the amount of kidney impairment. In my

case, high blood pressure runs in the family, on both sides, so it just made

the blood pressure all that much harder to control.

Pierre

Re: Question on BP meds in General

> thanks for the info Pierre. No I have not ever been on a beta

> blocker. I went to the Doctor today and they told me my 24 hour

> Protein was only 300mg. I often notice pretty heavy foam in my urine

> so I am confused as to how it is this low? I guess you can't judge

> it that way. Is there anything else that might cause Foamy Urine?

> Anyway my creatine was 1.9 and my creatine clearance 55. My blood

> pressure was high at 160/95. So the Doc. Increased my CLonidine

> to .2mg 4 times a day.

>

>

>

>

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Blood pressure also runs high in my family. When I was first

diagnosed my BP was 200/140. They used Clonidine as an emergency

drug to lower it while I was in the hospital. Since I seemed to

handle it fairly well they just left me on it. My blood pressure is

still very difficult to control. When I was in the hospital my 24

hour urine showed I was spilling about 3.4 grams of protein. That

has since gone all the way down to 300mg since I have been put on the

tiazac. It just baffels me because I was once on an ACE Inhibitor

for about 2 months and the foamy urine was gone completely. Now I

have lots of foam sometimes, but the Doc says only 300mg per

24hours. What is the Normal range for Protein Spillage for a Male

Adult anyway? Oh well I guess some things just don't need explained.

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None except perhaps trace amounts. There is no normal range for proteinuria.

Any protein spillage is considered abnormal.

I take the angiotensin II receptor blocker Avapro (irbesartan). Sometimes, I

have absolutely no foam whatsoever, sometimes quite a bit, at different

times of the day. And there is no pattern to it at all. I remember it was

the same when I was on various ACE inhibitors, and also Cardizem CD.

With BP meds, most doctors seem to operate on the principle of " if it ain't

broke, don't fix it " . They would rather increase the dosage or add something

else rather than have someone change meds.

There also seems to be a 's Law in effect. If a patient specifically

asks for a certain drug and gets it, you can bet that it just won't work out

: )

Pierre

Re: Question on BP meds in General

> Blood pressure also runs high in my family. When I was first

> diagnosed my BP was 200/140. They used Clonidine as an emergency

> drug to lower it while I was in the hospital. Since I seemed to

> handle it fairly well they just left me on it. My blood pressure is

> still very difficult to control. When I was in the hospital my 24

> hour urine showed I was spilling about 3.4 grams of protein. That

> has since gone all the way down to 300mg since I have been put on the

> tiazac. It just baffels me because I was once on an ACE Inhibitor

> for about 2 months and the foamy urine was gone completely. Now I

> have lots of foam sometimes, but the Doc says only 300mg per

> 24hours. What is the Normal range for Protein Spillage for a Male

> Adult anyway? Oh well I guess some things just don't need explained.

>

>

>

>

>

>

>

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