How high can you go with P5P?Have I gone too high? Dr. JM please advise!

[Guest guest]

Hello All,

My daughter is a little on the unique side.

My DAN! recommended B6 for my daughter. She does not have " the label "

of ASD but I treat her as such since she is metal toxic..... . She

has a lot of sensory issues, non verbal, and BALANCE issues- she is

3.5yo and not really walking very well yet. My DAN! recommended

8mg/lb and gave me P5P 50mg. He told me to increase it 1 tab a week.

So, we did, and had AWESOME results. Within 1-2 days of any of the

increases we saw more changes in balance, coordination...she was

starting to walk very well with no shoes on! We had NO problems with

it ( on Mag too). Her ABA reports from school came back better and

better. We were up to 200mg of P5P. Then I read in the 2005 ARI

Consensus Paper that regarding the B6, 8mg/lb, " typically only 1/5

that dosage is used " if using the P5P form. UGH. I have looked

back in the files, old posts..... and this does not seem to be

mentioned on this board.

Dr. JM had written April 17, 07 that " P5P with Mg is the non toxic

bioequivalent form, much better absorded than the B6 " . I called my

DAN! and he said he thought the dose was ok based on the response and

no side affects. He was not aware of what the consensus report

mentioned, he thought they could be interchangeable. Any thoughts?

CLinically, she looks outstanding and the major concern of neuropathy

with B6 does not seem to be an issue with P5P and she has diminished

sensation in her feet already, and if anything, the P5P, helping with

the balance, has seemed to override her issues with her feet as she

has been walking non stop!

Thanks for any feedback!

Kathy and -3.5yo, no formal diagnosis, but toxic with antimony,

uranium, nickel, aluminum, (lead and mercury elevated too) with all

the hypo- sensory issues, dyspraxia.

Been told by the " main stream " that she has an undiscovered genetic

disorder and that she actually looks " pretty good " (pretty good

eventhough she can't walk, talk, feed self, drink from a cup or

straw, feel much pain.... but she is quiet, and does not run

around... so she looks like the " perfect " child!

[Guest guest]

No problem; I have never heard of a toxic dose of B6

in this form; regular B6 can cause problems in high

doses. Dr. JM

--- kkolackovsky wrote:

> Hello All,

>

> My daughter is a little on the unique side.

>

> My DAN! recommended B6 for my daughter. She does not

> have " the label "

> of ASD but I treat her as such since she is metal

> toxic..... . She

> has a lot of sensory issues, non verbal, and BALANCE

> issues- she is

> 3.5yo and not really walking very well yet. My DAN!

> recommended

> 8mg/lb and gave me P5P 50mg. He told me to increase

> it 1 tab a week.

> So, we did, and had AWESOME results. Within 1-2 days

> of any of the

> increases we saw more changes in balance,

> coordination...she was

> starting to walk very well with no shoes on! We had

> NO problems with

> it ( on Mag too). Her ABA reports from school came

> back better and

> better. We were up to 200mg of P5P. Then I read in

> the 2005 ARI

> Consensus Paper that regarding the B6, 8mg/lb,

> " typically only 1/5

> that dosage is used " if using the P5P form. UGH.

> I have looked

> back in the files, old posts..... and this does not

> seem to be

> mentioned on this board.

>

> Dr. JM had written April 17, 07 that " P5P with Mg

> is the non toxic

> bioequivalent form, much better absorded than the

> B6 " . I called my

> DAN! and he said he thought the dose was ok based on

> the response and

> no side affects. He was not aware of what the

> consensus report

> mentioned, he thought they could be interchangeable.

> Any thoughts?

> CLinically, she looks outstanding and the major

> concern of neuropathy

> with B6 does not seem to be an issue with P5P and

> she has diminished

> sensation in her feet already, and if anything, the

> P5P, helping with

> the balance, has seemed to override her issues with

> her feet as she

> has been walking non stop!

>

> Thanks for any feedback!

>

> Kathy and -3.5yo, no formal diagnosis, but

> toxic with antimony,

> uranium, nickel, aluminum, (lead and mercury

> elevated too) with all

> the hypo- sensory issues, dyspraxia.

>

> Been told by the " main stream " that she has an

> undiscovered genetic

> disorder and that she actually looks " pretty good "

> (pretty good

> eventhough she can't walk, talk, feed self, drink

> from a cup or

> straw, feel much pain.... but she is quiet, and does

> not run

> around... so she looks like the " perfect " child!

>

>

[Guest guest]

Hi,

I hope you don't mind my butting in, but what kinds of problems can high doses

of B6 cause?

I think my 3.5 yo son was having problems with it--I was giving him 50 mg of B6

along with

about 10 mg P5P (the combo is recommended by ARI for oxalate issues). I think

it was

causing a major phenol reaction, so I took him off of it. He immediately

started sleeping

more soundly.

But now I've noticed a slow regression--more hyper, very red cheeks, not

sleeping as well,

running in circles, OCD, etc. He must need the B6--should I just give him the

P5P form

instead of the combo?

Thanks,

[Guest guest]

It takes very high doses for the main side effect of

peripheral neuralgia; I doubt if this is your son's

problem. I never give regular B6, and have never had

a problem with overdosing or side effects from the

P5P, though it must be given with mercury to be

absorbed. It comes in a formula by Klaire that

contains both P5P + Mag; most kids need only one

daily. Dr. JM

--- klt9751 wrote:

> Hi,

> I hope you don't mind my butting in, but what kinds

> of problems can high doses of B6 cause?

> I think my 3.5 yo son was having problems with it--I

> was giving him 50 mg of B6 along with

> about 10 mg P5P (the combo is recommended by ARI for

> oxalate issues). I think it was

> causing a major phenol reaction, so I took him off

> of it. He immediately started sleeping

> more soundly.

>

> But now I've noticed a slow regression--more hyper,

> very red cheeks, not sleeping as well,

> running in circles, OCD, etc. He must need the

> B6--should I just give him the P5P form

> instead of the combo?

>

> Thanks,

>

>

>

>

>

[Guest guest]

Dr. JM,

From your reply-

" ...P5P must be given with... " what????? I guess the " M " word is on ALL our

minds

-------------- Original message from JAQUELYN MCCANDLESS

: --------------

It takes very high doses for the main side effect of

peripheral neuralgia; I doubt if this is your son's

problem. I never give regular B6, and have never had

a problem with overdosing or side effects from the

P5P, though it must be given with mercury to be

absorbed. It comes in a formula by Klaire that

contains both P5P + Mag; most kids need only one

daily. Dr. JM

--- klt9751 wrote:

> Hi,

> I hope you don't mind my butting in, but what kinds

> of problems can high doses of B6 cause?

> I think my 3.5 yo son was having problems with it--I

> was giving him 50 mg of B6 along with

> about 10 mg P5P (the combo is recommended by ARI for

> oxalate issues). I think it was

> causing a major phenol reaction, so I took him off

> of it. He immediately started sleeping

> more soundly.

>

> But now I've noticed a slow regression--more hyper,

> very red cheeks, not sleeping as well,

> running in circles, OCD, etc. He must need the

> B6--should I just give him the P5P form

> instead of the combo?

>

> Thanks,

>

>

>

>

>

[Guest guest]

Omigoddess! I was just typing a long report on

mercury and do have it on my mind, and probably my

brain too. I meant magnesium, of course!! Sorry

about that! Dr. JM

--- FM wrote:

> Dr. JM,

> From your reply-

> " ...P5P must be given with... " what????? I guess the

> " M " word is on ALL our minds

>

> -------------- Original message from JAQUELYN

> MCCANDLESS : --------------

>

>

> It takes very high doses for the main side effect of

> peripheral neuralgia; I doubt if this is your son's

> problem. I never give regular B6, and have never had

> a problem with overdosing or side effects from the

> P5P, though it must be given with mercury to be

> absorbed. It comes in a formula by Klaire that

> contains both P5P + Mag; most kids need only one

> daily. Dr. JM

> --- klt9751 wrote:

>

> > Hi,

> > I hope you don't mind my butting in, but what

> kinds

> > of problems can high doses of B6 cause?

> > I think my 3.5 yo son was having problems with

> it--I

> > was giving him 50 mg of B6 along with

> > about 10 mg P5P (the combo is recommended by ARI

> for

> > oxalate issues). I think it was

> > causing a major phenol reaction, so I took him off

> > of it. He immediately started sleeping

> > more soundly.

> >

> > But now I've noticed a slow regression--more

> hyper,

> > very red cheeks, not sleeping as well,

> > running in circles, OCD, etc. He must need the

> > B6--should I just give him the P5P form

> > instead of the combo?

> >

> > Thanks,

> >

> >

> >

> >

> >

>

>

>

>

> [Non-text portions of this message have been

> removed]

>

>

>

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