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Intrauterine infections

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1: Orv Hetil. 2006 Sep 10;147(36):1723-30.

Intrauterine infections

[Article in Hungarian]

Jakobovits A.

Toldy Ferenc Kórház, Szülészeti es Nogyógyászati Osztály, Cegléd.

A broad variety of microorganisms are capable of causing fetal

infections. Among viral agents prominent are the human cytomegaly

virus (HCMV), herpes simplex virus (HSV), human immundeficiency virus

(HIV), varicella, herpes zooster, rubella, parvovirus B19, measles and the

hepatitis B and C viruses. Protozoa such as toxoplasma and

spirocheta pallida, causing congenital syphilis are equally important.

Bacterial infections are responsible for in uterus aquired

listeriosis, tuberculosis, and group B streptococcus infections. Fungi

including candida albicans complete the circle of infections

pathogens. Infectious microrganisms may reach the fetus through the

placenta are may ascend through the birth canal. The quoted

pathological agents threaten the health and life of the fetus directly by

the biological derangements they cause and also by inducing

abortion or premature birth. The clinical manifestations include

retarded growth, central nervous system damage and skin lesions. The

invariable therapeutic measures vary but in general, are limited value in

cases of in utero acquired infections.

PMID: 17087016

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