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Just looking for some feedback, here. I started on Methotrexate July

22. Currently I am also taking 2 5mg prednisone every day. (and

Plaquenil). My doctor said it could take 2 mos for Mtx to work. I was

feeling better with the prednisone but in the last week or 2, having

more pain in my hands and feet again. I started back to work last week

after being off all summer - I work in the schools which involves a lot

of walking and being on my feet - so maybe that has made things worse.

For those of you who have had success with Mtx, how long did it take to

notice a difference? Is there anyone who has had lasting positive

effects from Mtx? Also, is the low dose of prednisone I'm on enough to

lower my immune system significantly? Working in the schools, I get

exposed to a lot of things and hate to think I will easily pick up what

the kids have. Doc wants to leave me on prednisone a couple more

months until the Mtx kicks in. I don't go back to see him until mid

October so I thought I would throw these questions your way, to the

(unfortunately) experienced ones.

- in NC

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