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Enbrel 25mg VS 50mg

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Etanercept

Abstract #1947 Randomized controlled trial of 25 mg vs 50 mg Enbrel®

(etanercept) twice weekly in rheumatoid arthritis (RA) M Schiff, P

Mease, M Weinblatt, L Moreland, D Burge. Denver, Seattle, Boston,

Birmingham.

Etanercept is recommended currently at a dose of 25 mg twice weekly.

This study was undertaken to determine whether a higher dose is safe

and provides additional efficacy for treatment of RA. The bottom line

in this study was that patients treated with 50 mg twice weekly had

more rapid improvement in signs and symptoms of RA but, by the end of 6

months, responses were identical to those receiving 25 mg twice weekly.

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