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Hydergine

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Hi All

Apparently Hydergine assists brain function. Maybe more???

lef.org recommends it for Multiple Sclerosis and

Amyotrophic Lateral Sclerosis (ALS). Comments?

Hydergine

Hydergine is a drug approved by the FDA for persons over 60 who

manifest signs and symptoms of an idiopathic decline in mental

capacity. Studies have shown that it increases stores of the

universal energy molecule, adenosine triphosphate (ATP), stabilizes

the intracellular messenger molecule cyclic adenosine monophosphate

(cAMP) content of nerve cells, improves utilization of glucose in the

brain, and enhances cerebral microcirculation.

A study showed that Hydergine causes an increase of SOD and catalase

in the brain. SOD and catalase are the body's natural antioxidants

and are among the most effective free radical scavengers (Sozmen et

al. 1998).

What was interesting about this study is that Hydergine was

administered for only 20 days, but its effects on the brains of the

lab rats were dramatic. Hydergine specifically increased catalase

levels in the brain, as well as SOD in the hippocampus and in the

corpus striatum regions. Those regions of the brain suffer severe

oxidative damage from hydrogen peroxide and other free-radical

generating agents. Orally ingested SOD and catalase have not proven

efficacious because these antioxidant enzymes are broken down in the

stomach, so scientists have concentrated on ways of prompting the

body to produce its own cellular SOD and catalase. This study showed

that Hydergine could increase brain levels of SOD and catalase after

only short-term administration (Faloon 1998a).

Szpak

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