CASE REPORT - Rheumatoid nodulosis: report of two cases

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Journal of the European Academy of Dermatology & Venereology

Volume 17 Issue 6 Page 695 - November 2003

CASE REPORT

Rheumatoid nodulosis: report of two cases

MT Bordel Gómez, A Mariscal Polo, A Miranda Romero, J Vega Gutiérrez,

G Martínez García*

ABSTRACT

We present two patients with subcutaneous nodular lesions of several

years' duration. These lesions were well defined and painless and were

located next to bony surfaces or in the pulps of fingers and elbows. No

other symptoms were observed except for frequent attacks of palindromic

rheumatism with no evidence of arthritis or systemic manifestations

suggestive of rheumatoid arthritis. Other studies performed were normal with

negative results for rheumatoid factor and antinuclear antibodies.

Radiographs of affected sites showed no signs of arthritis while the

histopathologic study revealed some findings compatible with rheumatoid

nodule. One of the patients also presented desquamate papular lesions at the

level of elbows while histologically a process of transepidermal elimination

of fibrinoid could be observed. Our patients fulfil all the diagnostic

criteria for rheumatoid nodulosis as they present multiple rheumatoid

nodules confirmed on biopsy, symptoms of palindromic rheumatism, no evidence

of arthritis or radiological alterations and negative rheumatoid factor.

http://www.blackwell-synergy.com/links/doi/10.1046/j.1468-3083.2003.00705.x/abs/

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