CASE REPORT - B cell MALT lymphoma diagnosed by LSG biopsy in patients screened for Sjogren's syndrome

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Ann Rheum Dis. 2005 Mar;64(3):471-3.

B cell MALT lymphoma diagnosed by labial minor salivary gland biopsy in

patients screened for Sjogren's syndrome.

Van Mello NM, Pillemer SR, Tak PP, Sankar V.

Gene Therapy and Therapeutics Branch, National Institute of Dental and

Craniofacial Research, National Institutes of Health, DHHS, Bethesda, MD

20892, USA.

CASE REPORT: Three patients presented to the Sjogren's syndrome (SS) Clinic

at the National Institute of Dental and Craniofacial Research for screening.

The records of patients with SS with a diagnosis of lymphoma were examined

to determine whether the diagnosis was made in any of the cases as a result

of labial salivary gland (LSG) biopsies. All patients had typical features

of primary SS according to the American-European Consensus Group criteria. B

cell mucosa associated lymphoid tissue (MALT) lymphoma was diagnosed based

upon the LSG biopsy.

CONCLUSION: This report underlines the advantages of performing LSG biopsies

as a routine part of screening for SS, and shows that it may in some

instances lead to early diagnosis of MALT lymphomas in patients who show no

signs of pre-existing lymphoma.

PMID: 15708896

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=1\

5708896 & dopt=Abstract

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