Guest guest Posted March 6, 2005 Report Share Posted March 6, 2005 Faith, I started on Methotrexate 6 weeks ago. I took 7.5 mg for 5 weeks, then had blood work again. Dr, just increased the dose by 2.5--so now he has me on 10 mg for another 5 weeks. I have to tell you, that for pain in my extremities, hands, fingers feet, toes, arms, neck and shoulders, I have NO relief yet at all. But what I describe as " deep " pain---I do have some relief. Deep, like I had terrible pain from tendonitis (RA related) in both hips and groins for over 1 1/2 years--that pain is somewhat improved. My elbows are a bit better as is my back. Nothing to write home about really, but instead of the 24/7 burning amd aching, it's now like 22/7. Debbie McCandless 's Ridge LaManchas Titusville, PA www.ryansridge.com ********************************************************************************\ ********************************************************************************\ ******************************************************************* This message and any attachments are solely for the intended recipient. If you are not the intended recipient, disclosure, copying, use or distribution of the information included in this message is prohibited -- Please immediately and permanently delete. ********************************************************************************\ ********************************************************************************\ ********************************************************************************\ ********************************************************************************\ **************************************************************************** [ ] METHO. how long before it works? Hi group, I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills (15 mg) per week. I know it takes awhile to take affect. I would like to know what experience most have had here with the length of time on methotrexate prior to getting some relief. As of today I have not experienced much relief. Is this usual to take this long before one starts feeling any benefit from the drug? Faith Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 6, 2005 Report Share Posted March 6, 2005 Faith, I started on Methotrexate 6 weeks ago. I took 7.5 mg for 5 weeks, then had blood work again. Dr, just increased the dose by 2.5--so now he has me on 10 mg for another 5 weeks. I have to tell you, that for pain in my extremities, hands, fingers feet, toes, arms, neck and shoulders, I have NO relief yet at all. But what I describe as " deep " pain---I do have some relief. Deep, like I had terrible pain from tendonitis (RA related) in both hips and groins for over 1 1/2 years--that pain is somewhat improved. My elbows are a bit better as is my back. Nothing to write home about really, but instead of the 24/7 burning amd aching, it's now like 22/7. Debbie McCandless 's Ridge LaManchas Titusville, PA www.ryansridge.com ********************************************************************************\ ********************************************************************************\ ******************************************************************* This message and any attachments are solely for the intended recipient. If you are not the intended recipient, disclosure, copying, use or distribution of the information included in this message is prohibited -- Please immediately and permanently delete. ********************************************************************************\ ********************************************************************************\ ********************************************************************************\ ********************************************************************************\ **************************************************************************** [ ] METHO. how long before it works? Hi group, I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills (15 mg) per week. I know it takes awhile to take affect. I would like to know what experience most have had here with the length of time on methotrexate prior to getting some relief. As of today I have not experienced much relief. Is this usual to take this long before one starts feeling any benefit from the drug? Faith Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 For me it took about 6 weeks to cut in and it worked for about years. n France [ ] METHO. how long before it works? Hi group, I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills (15 mg) per week. I know it takes awhile to take affect. I would like to know what experience most have had here with the length of time on methotrexate prior to getting some relief. As of today I have not experienced much relief. Is this usual to take this long before one starts feeling any benefit from the drug? Faith Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 For me it took about 6 weeks to cut in and it worked for about years. n France [ ] METHO. how long before it works? Hi group, I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills (15 mg) per week. I know it takes awhile to take affect. I would like to know what experience most have had here with the length of time on methotrexate prior to getting some relief. As of today I have not experienced much relief. Is this usual to take this long before one starts feeling any benefit from the drug? Faith Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 Sorry - that was supposed to say 'about 8 years' ! n France [ ] METHO. how long before it works? Hi group, I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills (15 mg) per week. I know it takes awhile to take affect. I would like to know what experience most have had here with the length of time on methotrexate prior to getting some relief. As of today I have not experienced much relief. Is this usual to take this long before one starts feeling any benefit from the drug? Faith Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 Sorry - that was supposed to say 'about 8 years' ! n France [ ] METHO. how long before it works? Hi group, I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills (15 mg) per week. I know it takes awhile to take affect. I would like to know what experience most have had here with the length of time on methotrexate prior to getting some relief. As of today I have not experienced much relief. Is this usual to take this long before one starts feeling any benefit from the drug? Faith Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 Faith, This is from Hopkins Arthritis site: Usual Time to Effect: The onset of action is 4 to 6 weeks, with 70% of patients having some response. A trial of 3 to 6 months is suggested. http://www.hopkins-arthritis.som.jhmi.edu/rheumatoid/rheum_treat.html#dmards a On Mon, 07 Mar 2005 04:03:54 +0000, fmt2002@... <fmt2002@...> wrote: > Hi group, > I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills > (15 mg) per week. I know it takes awhile to take affect. I would like to > know what experience most have had here with the length of time on > methotrexate prior to getting some relief. As of today I have not > experienced much relief. Is this usual to take this long before one starts > feeling any benefit from the drug? > Faith > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 Faith, This is from Hopkins Arthritis site: Usual Time to Effect: The onset of action is 4 to 6 weeks, with 70% of patients having some response. A trial of 3 to 6 months is suggested. http://www.hopkins-arthritis.som.jhmi.edu/rheumatoid/rheum_treat.html#dmards a On Mon, 07 Mar 2005 04:03:54 +0000, fmt2002@... <fmt2002@...> wrote: > Hi group, > I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills > (15 mg) per week. I know it takes awhile to take affect. I would like to > know what experience most have had here with the length of time on > methotrexate prior to getting some relief. As of today I have not > experienced much relief. Is this usual to take this long before one starts > feeling any benefit from the drug? > Faith > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 thank you a this article is helpful... Thanks to everyone that has responded. It sure helps to read about personal experiences as well. Faith -------------- Original message -------------- Faith, This is from Hopkins Arthritis site: Usual Time to Effect: The onset of action is 4 to 6 weeks, with 70% of patients having some response. A trial of 3 to 6 months is suggested. http://www.hopkins-arthritis.som.jhmi.edu/rheumatoid/rheum_treat.html#dmards a On Mon, 07 Mar 2005 04:03:54 +0000, fmt2002@... <fmt2002@...> wrote: > Hi group, > I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills > (15 mg) per week. I know it takes awhile to take affect. I would like to > know what experience most have had here with the length of time on > methotrexate prior to getting some relief. As of today I have not > experienced much relief. Is this usual to take this long before one starts > feeling any benefit from the drug? > Faith > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 thank you a this article is helpful... Thanks to everyone that has responded. It sure helps to read about personal experiences as well. Faith -------------- Original message -------------- Faith, This is from Hopkins Arthritis site: Usual Time to Effect: The onset of action is 4 to 6 weeks, with 70% of patients having some response. A trial of 3 to 6 months is suggested. http://www.hopkins-arthritis.som.jhmi.edu/rheumatoid/rheum_treat.html#dmards a On Mon, 07 Mar 2005 04:03:54 +0000, fmt2002@... <fmt2002@...> wrote: > Hi group, > I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills > (15 mg) per week. I know it takes awhile to take affect. I would like to > know what experience most have had here with the length of time on > methotrexate prior to getting some relief. As of today I have not > experienced much relief. Is this usual to take this long before one starts > feeling any benefit from the drug? > Faith > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 Faith, I also take 6 Methotrexate per week. It took about 3 to 4 months before I felt any effects. My arthritis is all in my hands. I noticed a very gradual improvement in the pain. Now I am at the point where I don't usually have any pain in my hands except occasional twinges and I don't take any pain meds. However, I do have the enlarged knuckles and both small fingers are sort of twisted. I don't think that has gotten worse over the last 6 months. I try to take a picture of my hands every 2 months or so for comparison. Kathy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 Faith, It also took me about 6 weeks to tell a difference. I hope you start seeing some relief soon. Tawny > Hi group, > I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills (15 mg) per week. I know it takes awhile to take affect. I would like to know what experience most have had here with the length of time on methotrexate prior to getting some relief. As of today I have not experienced much relief. Is this usual to take this long before one starts feeling any benefit from the drug? > Faith > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2005 Report Share Posted March 7, 2005 Faith, It also took me about 6 weeks to tell a difference. I hope you start seeing some relief soon. Tawny > Hi group, > I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 pills (15 mg) per week. I know it takes awhile to take affect. I would like to know what experience most have had here with the length of time on methotrexate prior to getting some relief. As of today I have not experienced much relief. Is this usual to take this long before one starts feeling any benefit from the drug? > Faith > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 13, 2005 Report Share Posted March 13, 2005 Hi I can't remember how long it took for methotrexate to work, but it seemed like a while, quite a few months I would say, I was just taking celebrex everyday, but once the methotrexate started kicking in, I could reduce the celebrex to every couple of days, to now where I don't need to take it at all with 12.5mg methotrexate. I have found methotrexate makes you feel pretty yucky, but has definitely improved my pain and movement, so worth it in the end > > Hi group, > > I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 > pills (15 mg) per week. I know it takes awhile to take affect. I > would like to know what experience most have had here with the length > of time on methotrexate prior to getting some relief. As of today I > have not experienced much relief. Is this usual to take this long > before one starts feeling any benefit from the drug? > > Faith > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 13, 2005 Report Share Posted March 13, 2005 Hi I can't remember how long it took for methotrexate to work, but it seemed like a while, quite a few months I would say, I was just taking celebrex everyday, but once the methotrexate started kicking in, I could reduce the celebrex to every couple of days, to now where I don't need to take it at all with 12.5mg methotrexate. I have found methotrexate makes you feel pretty yucky, but has definitely improved my pain and movement, so worth it in the end > > Hi group, > > I started Methotrexate 4 weeks ago for the treatment of RA.I take 6 > pills (15 mg) per week. I know it takes awhile to take affect. I > would like to know what experience most have had here with the length > of time on methotrexate prior to getting some relief. As of today I > have not experienced much relief. Is this usual to take this long > before one starts feeling any benefit from the drug? > > Faith > > > > Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.