Guest guest Posted November 8, 2006 Report Share Posted November 8, 2006 Been a rough 2 days...woke up yesterday feeling like I could only inhale so much air...there was nowhere to put it once I breathed in. I felt nauseated and tired all day. When I am still, I hear myself panting for air, breathing really fast and shallow. Had to go to WalMart for some meds and realized that when I usually get 2 hrs. on an E tank, I only got an hr and a half yesterday. First time I ever coughed up anything, seemed I felt better after I coughed up this junk. I really am breathing faster, I noticed that first thing. It's not a realaxed breathing. You can imagine how it is with exertion. I was thinking about Vicky's desire for one more Christmas...today I ask for one more Thanksgiving, or for the one more Chat nite with the group. I guess...no, I fear, the end is near. I am suppose to start rehab on the 20th,...lol. My best friend wants me to go to ER ,but I am afraid they will put me on a vent and won't be able to take me off of it. And there I'll be... I am waiting for my new primary Dr. to call with the approval of 750mgs of Levaquuin for a few days. Maybe that will help. I love you all, thank you for allowing me to vent here. So scary, fear grips me and it is such a battle for me....I covet your prayers...and it is such a comfort to know I am not alone. kiss kiss, Ginger 9/04 ipf Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2006 Report Share Posted November 8, 2006 Oh Ginger, No wonder you've been on my mind so much lately. I'm sorry that you are having such a hard time. This disease SUCKS! I pray for you (and the rest of the gang) each and every night and sometimes during the day. I wish I could just come over there and give you a great big hug. Please know that you are never far from my thoughts and prayers. Love, Leanne uip 1/03TongueDancer2U@... wrote: Been a rough 2 days...woke up yesterday feeling like I could only inhale so much air...there was nowhere to put it once I breathed in. I felt nauseated and tired all day. When I am still, I hear myself panting for air, breathing really fast and shallow. Had to go to WalMart for some meds and realized that when I usually get 2 hrs. on an E tank, I only got an hr and a half yesterday. First time I ever coughed up anything, seemed I felt better after I coughed up this junk. I really am breathing faster, I noticed that first thing. It's not a realaxed breathing. You can imagine how it is with exertion. I was thinking about Vicky's desire for one more Christmas...today I ask for one more Thanksgiving, or for the one more Chat nite with the group. I guess...no, I fear, the end is near. I am suppose to start rehab on the 20th,...lol. My best friend wants me to go to ER ,but I am afraid they will put me on a vent and won't be able to take me off of it. And there I'll be... I am waiting for my new primary Dr. to call with the approval of 750mgs of Levaquuin for a few days. Maybe that will help. I love you all, thank you for allowing me to vent here. So scary, fear grips me and it is such a battle for me....I covet your prayers...and it is such a comfort to know I am not alone. kiss kiss, Ginger 9/04 ipf Sponsored Link Talk more and pay less. Vonage can save you up to $300 a year on your phone bill. Sign up now. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2006 Report Share Posted November 8, 2006 Ginger, You know that you are not ALONE. First of all, our Heavenly Father is with you and secondly, all of us here love you and are with you in spirit. RE: First time I ever coughed up anything, seemed I felt better after I > coughed up this junk As you know, I bring up lots of 'junk' and right before I nebulize and use the flutter valve, etc. I can hardly get a breath. I will put it off because I get so sick and tired of it, but it really helps. I also have learned that when the 'junk' gets more abundant, it usually means an infection brewing. So, glad you are starting on the Levaquin. My doc gives me a standing prescription so that I do not have to wait when I suspect a problem. He says to always err on the side of caution. I think one is wise to avoid the emergency room...unless perhaps if it is a major heart/lung center. That ventilator thing scares me too. This fear that we have is justified and real. I know that we as Christians are not to fear, but the same God that inspired the writers of his word, that instructs us not to fear is the same God who made human beings with human emotions. He hears and understands our groanings. I am with you Ginger....you are in my heart. Reach out your hand and I will be holding it. I will pray that God will pull you through and give you many more Thanksgivings and abundant peace. Hugs and love, Joyce PF 1997 Bronchiectasis 2004 >> Been a rough 2 days...woke up yesterday feeling like I could only inhale so > much air...there was nowhere to put it once I breathed in. I felt nauseated > and tired all day. When I am still, I hear myself panting for air, breathing > really fast and shallow. Had to go to WalMart for some meds and realized that > when I usually get 2 hrs. on an E tank, I only got an hr and a half > yesterday. First time I ever coughed up anything, seemed I felt better after I > coughed up this junk. I really am breathing faster, I noticed that first thing. > It's not a realaxed breathing. You can imagine how it is with exertion.> I was thinking about Vicky's desire for one more Christmas...today I ask > for one more Thanksgiving, or for the one more Chat nite with the group. I > guess...no, I fear, the end is near. I am suppose to start rehab on the > 20th,...lol. My best friend wants me to go to ER ,but I am afraid they will put me > on a vent and won't be able to take me off of it. And there I'll be...> I am waiting for my new primary Dr. to call with the approval of 750mgs > of Levaquuin for a few days. Maybe that will help.> I love you all, thank you for allowing me to vent here. So scary, fear > grips me and it is such a battle for me....I covet your prayers...and it is > such a comfort to know I am not alone.> kiss kiss,> Ginger 9/04 ipf> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2006 Report Share Posted November 8, 2006 Ginger, I hate to hear you are having such a hard time. Extra prayers on the way up. God grant you peace. Love and Prayers, Peggy 9/04 ipf Been a rough 2 days...woke up yesterday feeling like I could only inhale so much air...there was nowhere to put it once I breathed in. I felt nauseated and tired all day. When I am still, I hear myself panting for air, breathing really fast and shallow. Had to go to WalMart for some meds and realized that when I usually get 2 hrs. on an E tank, I only got an hr and a half yesterday. First time I ever coughed up anything, seemed I felt better after I coughed up this junk. I really am breathing faster, I noticed that first thing. It's not a realaxed breathing. You can imagine how it is with exertion. I was thinking about Vicky's desire for one more Christmas...today I ask for one more Thanksgiving, or for the one more Chat nite with the group. I guess...no, I fear, the end is near. I am suppose to start rehab on the 20th,...lol. My best friend wants me to go to ER ,but I am afraid they will put me on a vent and won't be able to take me off of it. And there I'll be... I am waiting for my new primary Dr. to call with the approval of 750mgs of Levaquuin for a few days. Maybe that will help. I love you all, thank you for allowing me to vent here. So scary, fear grips me and it is such a battle for me....I covet your prayers...and it is such a comfort to know I am not alone. kiss kiss, Ginger 9/04 ipf Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2006 Report Share Posted November 8, 2006 Ginger, YOu will always have my prayers and be in them. I understand how you feel, I'm still wondering if I will make it to Christmas. I found out my daughter is paying to fly my son and daughter in law up here from Texas for Christmas, but will I be here? I still struggle to breathe, it hurts to breathe and the depression is getting so bad, my husband almost admitted me to the Fieldstone tonite ( a mental health hosp). Ginger you have been a Godsend to me and many others on here, remember what you tell us, you are not alone NO MATTER WHERE YOU ARE IN THIS DISEASE. God is with you, holding you close, we love you and lift you up in prayer....... Vicky81856 IPH/PF PH 4/06 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2006 Report Share Posted November 8, 2006 Dear Ginger: I dont remember if you said you take a mucolytic agent to thin the mucous secretions so you can cough them up easier and have less difficulty with chest congestion. If not I have included some information below about them. It is important not to take a cough suppressant as that prevents you from coughing up the mucous and the mucous is what attracts bacteria and subsequently infection into the lungs. A mucolytic agent however thins the mucous so the "cilia" (hairs in the bronchial tubes) can pull the secretions up to where they can be coughed out. The thinner the mucous the easier it is for the cilia, or hairs, to pull the mucous up so you can cough it out. I hope some of this information will be of help as it sounds like if you could loosen the mucous so as to cough it up easier you could breathe better. Hugs, Carolyn MUCOLYTICS The high viscosity of sputum in certain respiratory diseases is largely due to the mucoproteins found in pulmonary secretions. One of the early substances studied was L-cysteine, a naturally occurring amino acid. The results of L-cysteine were very favorable in terms of its ability to break the proteinaceous bonds within sputum; however, it had substantial irritating properties. These irritating properties were minimized by chemically altering the acid into an acetyl form. The resultant N-acetylcysteine is the generic name of Mucomyst. Within the protein molecules of sputum, there are two chains of proteins held together with a disulfide bond; that is, both chains have a sulfur atom such that the two sulfur atoms bind together. Mucomyst breaks up the chain by replacing the sulfurs with weaker bonds between sulfhydryl molecules. Mucomyst is available in a 10% and a 20% solution; the 10% is just as effective as the 20% solution, while the latter exhibits stronger tendencies toward irritation and bronchospasm. Therefore, it is common to nebulize 3-5 cc of the 10% solution, or dilute the 20% solution to make a 10% solution. It is most common, and very advisable, to co-administer a beta agonist brochodilator with Mucomyst to minimize bronchospastic side effects, although the Mucomyst package insert specifically states this is unnecessary. The most frequently used expectorant, or mucolytic agent is guaifenesin (glyceryl guaiacolate). Some doctors however do not like ILD patients to use this drug. True mucolytics are drugs intended to control mucus and bronchial secretions. The two primary agents approved for administration as aerosols to treat abnormal pulmonary secretions are acetylcysteine and dornase alfa. Both act to disrupt the disulfide bond in mucus and break down DNA materials in airway secretions. Acetylcysteine (Mucomyst) is an aerosolized medication indicated for treatment of the thick, purulent, viscous mucus secretions that can occur in COPD, especially chronic bronchitis, tuberculosis, cystic fibrosis, and acute tracheobronchitis. It is also administered orally as an antidote to reduce hepatic injury with overdoses of acetaminophen, and is designated as an orphan drug. Aerosol doses of Mucomyst are available in either 10 or 20% solutions, and normal dosage with 20% solution is 3-5 ml TID or QID, and 6-10 ml TID or QID with the 10% solution. The most serious potential side effect is bronchospasm, especially with hyperreactive airways seen in asthmatics, so using bronchodilators mixed with acetylcysteine or administer previously by MDI or nebulizer is recommended. Other potential side effects include stomatitis, nausea, and rhinorrhea. Dornase Alfa (Pulmozyme) is an orphan drug that was produced by recombinant DNA techniques, and is indicated for the treatment and management of the viscid respiratory secretions seen in patients with cystic fibrosis (CF). In CF patients, Pulmozyme helps reduce the frequency of respiratory infections requiring parenteral antibiotics, and generally improves their overall pulmonary function. Pulmozyme available as a single use ampule, with 2.5 mg drug in 2.5 ml of clear solution. Recommended dosage is 2.5 mg daily, delivered by nebulizers specifically approved for this use. Few side effects have been observed, including voice alteration, pharyngitis, laryngitis, rash, chest pain, and conjunctivitis. There are some home remedies that work as mucolytic agents such as spices, garlic, or onion. All these agents work by irritating the lining of the stomach, thereby stimulating the afferent fibers of the vagus nerve. Impulses sent to the CNS elicit an efferent vagal response, stimulating bronchial glands to increase secretion. The secretions moisten and loosen the mucous in the lungs. Been a rough 2 days...woke up yesterday feeling like I could only inhale so much air...there was nowhere to put it once I breathed in. I felt nauseated and tired all day. When I am still, I hear myself panting for air, breathing really fast and shallow. Had to go to WalMart for some meds and realized that when I usually get 2 hrs. on an E tank, I only got an hr and a half yesterday. First time I ever coughed up anything, seemed I felt better after I coughed up this junk. I really am breathing faster, I noticed that first thing. It's not a realaxed breathing. You can imagine how it is with exertion. I was thinking about Vicky's desire for one more Christmas...today I ask for one more Thanksgiving, or for the one more Chat nite with the group. I guess...no, I fear, the end is near. I am suppose to start rehab on the 20th,...lol. My best friend wants me to go to ER ,but I am afraid they will put me on a vent and won't be able to take me off of it. And there I'll be... I am waiting for my new primary Dr. to call with the approval of 750mgs of Levaquuin for a few days. Maybe that will help. I love you all, thank you for allowing me to vent here. So scary, fear grips me and it is such a battle for me....I covet your prayers...and it is such a comfort to know I am not alone. kiss kiss, Ginger 9/04 ipf Sponsored Link Talk more and pay less. Vonage can save you up to $300 a year on your phone bill. Sign up now. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2006 Report Share Posted November 8, 2006 Vicky, Repeat after me! I am going to have a wonderful Christmas. I know it, I know it, I know it!! And smile! Hugs and many prayers, Joyce >> Ginger,> > YOu will always have my prayers and be in them. I understand how you feel, > I'm still wondering if I will make it to Christmas. I found out my daughter is > paying to fly my son and daughter in law up here from Texas for Christmas, > but will I be here? I still struggle to breathe, it hurts to breathe and the > depression is getting so bad, my husband almost admitted me to the Fieldstone > tonite ( a mental health hosp). Ginger you have been a Godsend to me and > many others on here, remember what you tell us, you are not alone NO MATTER > WHERE YOU ARE IN THIS DISEASE. God is with you, holding you close, we love you > and lift you up in prayer.......> > Vicky81856 IPH/PF PH 4/06> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2006 Report Share Posted November 8, 2006 Dear Vicky, May God's angels hold you and keep you til you enjoy the warmth of the holiday season, I will have you in my prayers. Just remember christmas is the birthday of christ and you will live to see the day. HP 6/06Joyce wrote: Vicky, Repeat after me! I am going to have a wonderful Christmas. I know it, I know it, I know it!! And smile! Hugs and many prayers, Joyce >> Ginger,> > YOu will always have my prayers and be in them. I understand how you feel, > I'm still wondering if I will make it to Christmas. I found out my daughter is > paying to fly my son and daughter in law up here from Texas for Christmas, > but will I be here? I still struggle to breathe, it hurts to breathe and the > depression is getting so bad, my husband almost admitted me to the Fieldstone > tonite ( a mental health hosp). Ginger you have been a Godsend to me and > many others on here, remember what you tell us, you are not alone NO MATTER > WHERE YOU ARE IN THIS DISEASE. God is with you, holding you close, we love you > and lift you up in prayer.......> > Vicky81856 IPH/PF PH 4/06> Sponsored Link For just $24.99/mo., Vonage offers unlimited local and long- distance calling. Sign up now. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2006 Report Share Posted November 8, 2006 Vicky where in Texas is your son? Keep your chin up girl and fight this thing with everything in you. EG > > Ginger, > > YOu will always have my prayers and be in them. I understand how you feel, > I'm still wondering if I will make it to Christmas. I found out my daughter is > paying to fly my son and daughter in law up here from Texas for Christmas, > but will I be here? I still struggle to breathe, it hurts to breathe and the > depression is getting so bad, my husband almost admitted me to the Fieldstone > tonite ( a mental health hosp). Ginger you have been a Godsend to me and > many others on here, remember what you tell us, you are not alone NO MATTER > WHERE YOU ARE IN THIS DISEASE. God is with you, holding you close, we love you > and lift you up in prayer....... > > Vicky81856 IPH/PF PH 4/06 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 My son is in Wiley, a sub burb of Dallas i think...i sure do miss him... Vicky Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 Ginger, I am so sorry that you are having such a rough time of it. I will keep you in my prayers and I am sure that everyone on this board is doing the same. You are not alone and everyone here is thankful that you are with us. We just wish it were for reasons other than this monster of a disease. It would have been nice to have met each other on a web site for survivors of this monster, but alas at this point in time we do have any hope of that, but who knows what God has in store for us tomorrow. One of the researchers out there may find a cure and them we will all be survivors. If not then we will all be friends and help each other over the rough spots with prayer and an extra helping of love. You just keep on keeping on and God will do the rest. Remember that we will not leave this world one min before or one min after He is ready for us. Barbara R IPF 1/2003 > > Been a rough 2 days...woke up yesterday feeling like I could only inhale so > much air...there was nowhere to put it once I breathed in. I felt nauseated > and tired all day. When I am still, I hear myself panting for air, breathing > really fast and shallow. Had to go to WalMart for some meds and realized that > when I usually get 2 hrs. on an E tank, I only got an hr and a half > yesterday. First time I ever coughed up anything, seemed I felt better after I > coughed up this junk. I really am breathing faster, I noticed that first thing. > It's not a realaxed breathing. You can imagine how it is with exertion. > I was thinking about Vicky's desire for one more Christmas...today I ask > for one more Thanksgiving, or for the one more Chat nite with the group. I > guess...no, I fear, the end is near. I am suppose to start rehab on the > 20th,...lol. My best friend wants me to go to ER ,but I am afraid they will put me > on a vent and won't be able to take me off of it. And there I'll be... > I am waiting for my new primary Dr. to call with the approval of 750mgs > of Levaquuin for a few days. Maybe that will help. > I love you all, thank you for allowing me to vent here. So scary, fear > grips me and it is such a battle for me....I covet your prayers...and it is > such a comfort to know I am not alone. > kiss kiss, > Ginger 9/04 ipf > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 Barbara, What a good thought! I will try to remember that on my fearful days! Hugs, Joyce PF 1997 Bronchiectasis 2004 > >> > Been a rough 2 days...woke up yesterday feeling like I could only > inhale so > > much air...there was nowhere to put it once I breathed in. I felt > nauseated > > and tired all day. When I am still, I hear myself panting for > air, breathing > > really fast and shallow. Had to go to WalMart for some meds and > realized that > > when I usually get 2 hrs. on an E tank, I only got an hr and a > half > > yesterday. First time I ever coughed up anything, seemed I felt > better after I > > coughed up this junk. I really am breathing faster, I noticed that > first thing. > > It's not a realaxed breathing. You can imagine how it is with > exertion.> > I was thinking about Vicky's desire for one more > Christmas...today I ask > > for one more Thanksgiving, or for the one more Chat nite with the > group. I > > guess...no, I fear, the end is near. I am suppose to start rehab > on the > > 20th,...lol. My best friend wants me to go to ER ,but I am afraid > they will put me > > on a vent and won't be able to take me off of it. And there I'll > be...> > I am waiting for my new primary Dr. to call with the approval > of 750mgs > > of Levaquuin for a few days. Maybe that will help.> > I love you all, thank you for allowing me to vent here. So > scary, fear > > grips me and it is such a battle for me....I covet your > prayers...and it is > > such a comfort to know I am not alone.> > kiss kiss,> > Ginger 9/04 ipf> >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 Dallas you say??????? that's where the transplant hospital is. > > My son is in Wiley, a sub burb of Dallas i think...i sure do miss him... > > Vicky > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 Joyce, when I first was diagnosed with IPF my oldest grand daughter would call me from Madison, WI everyday and ask me " Nana you aren't going to die today are you? " and it just broke my heart for her to be so young, (she was only 13 at the time) and to be so worried about her Nana. For a while I didn't know what to say to her but after about 2 weeks of praying about it that is what I finally told her and she found peace in that and stopped worrying so much about her Nana dying today. She still worries about me not being there for her high graduation or her getting married, having kids and opening her first dance studio, but she knows I love her and that I will be around for as many of those things as God sees fit to let me. Our doctors mean well with their predictions of 3 to 5 years after diagnoses, but out lives are in Gods hands and He knows when we will depart from this life that we live. Keep a good attitude and keep praying. That is what my Pulm tells me when I leave his office after a visit. Hugs and Prayers! Barbara R IPF 1/2003 > > > > > > Been a rough 2 days...woke up yesterday feeling like I could only > > inhale so > > > much air...there was nowhere to put it once I breathed in. I felt > > nauseated > > > and tired all day. When I am still, I hear myself panting for > > air, breathing > > > really fast and shallow. Had to go to WalMart for some meds and > > realized that > > > when I usually get 2 hrs. on an E tank, I only got an hr and a > > half > > > yesterday. First time I ever coughed up anything, seemed I felt > > better after I > > > coughed up this junk. I really am breathing faster, I noticed that > > first thing. > > > It's not a realaxed breathing. You can imagine how it is with > > exertion. > > > I was thinking about Vicky's desire for one more > > Christmas...today I ask > > > for one more Thanksgiving, or for the one more Chat nite with the > > group. I > > > guess...no, I fear, the end is near. I am suppose to start rehab > > on the > > > 20th,...lol. My best friend wants me to go to ER ,but I am afraid > > they will put me > > > on a vent and won't be able to take me off of it. And there I'll > > be... > > > I am waiting for my new primary Dr. to call with the approval > > of 750mgs > > > of Levaquuin for a few days. Maybe that will help. > > > I love you all, thank you for allowing me to vent here. So > > scary, fear > > > grips me and it is such a battle for me....I covet your > > prayers...and it is > > > such a comfort to know I am not alone. > > > kiss kiss, > > > Ginger 9/04 ipf > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 Everybody sing!!!!! Vicky, Oooooh.....Christmas time's a comin' Christmas time's a comin' Christmas time's a comin' And Wiley is comin' too!!! Joyce God loves you Vicky and so do we!!!>> My son is in Wiley, a sub burb of Dallas i think...i sure do miss him...> > Vicky> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2006 Report Share Posted November 9, 2006 Ginger, What to say?? I hear you, what you express is entirely appropriate for what you are going through. You are in my prayers. I'm so glad you have Dusty! Love and blessings. Sher ipf 5-06 Re: Breathless Been a rough 2 days...woke up yesterday feeling like I could only inhale so much air...there was nowhere to put it once I breathed in. I felt nauseated and tired all day. When I am still, I hear myself panting for air, breathing really fast and shallow. Had to go to WalMart for some meds and realized that when I usually get 2 hrs. on an E tank, I only got an hr and a half yesterday. First time I ever coughed up anything, seemed I felt better after I coughed up this junk. I really am breathing faster, I noticed that first thing. It's not a realaxed breathing. You can imagine how it is with exertion. I was thinking about Vicky's desire for one more Christmas...today I ask for one more Thanksgiving, or for the one more Chat nite with the group. I guess...no, I fear, the end is near. I am suppose to start rehab on the 20th,...lol. My best friend wants me to go to ER ,but I am afraid they will put me on a vent and won't be able to take me off of it. And there I'll be... I am waiting for my new primary Dr. to call with the approval of 750mgs of Levaquuin for a few days. Maybe that will help. I love you all, thank you for allowing me to vent here. So scary, fear grips me and it is such a battle for me....I covet your prayers...and it is such a comfort to know I am not alone. kiss kiss, Ginger 9/04 ipf Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 10, 2006 Report Share Posted November 10, 2006 Carolyn, Was wondering.... the information on mucolytics that you provided mentioned that some doctors object to the use of guaifenesin by patients with ILD. Do you know what the objection is? My doctor has actually told me to take Mucinex or the store brand guaifenesin. I'm just curious about what the issue is with this drug and our group of lung diseases? Do you know? Beth (Fibrotic NSIP 06/06)Draw close. Hold hands. Life is short. God is good. Re: Breathless Dear Ginger: I dont remember if you said you take a mucolytic agent to thin the mucous secretions so you can cough them up easier and have less difficulty with chest congestion. If not I have included some information below about them. It is important not to take a cough suppressant as that prevents you from coughing up the mucous and the mucous is what attracts bacteria and subsequently infection into the lungs. A mucolytic agent however thins the mucous so the "cilia" (hairs in the bronchial tubes) can pull the secretions up to where they can be coughed out. The thinner the mucous the easier it is for the cilia, or hairs, to pull the mucous up so you can cough it out. I hope some of this information will be of help as it sounds like if you could loosen the mucous so as to cough it up easier you could breathe better. Hugs, Carolyn MUCOLYTICS The high viscosity of sputum in certain respiratory diseases is largely due to the mucoproteins found in pulmonary secretions. One of the early substances studied was L-cysteine, a naturally occurring amino acid. The results of L-cysteine were very favorable in terms of its ability to break the proteinaceous bonds within sputum; however, it had substantial irritating properties. These irritating properties were minimized by chemically altering the acid into an acetyl form. The resultant N-acetylcysteine is the generic name of Mucomyst. Within the protein molecules of sputum, there are two chains of proteins held together with a disulfide bond; that is, both chains have a sulfur atom such that the two sulfur atoms bind together. Mucomyst breaks up the chain by replacing the sulfurs with weaker bonds between sulfhydryl molecules. Mucomyst is available in a 10% and a 20% solution; the 10% is just as effective as the 20% solution, while the latter exhibits stronger tendencies toward irritation and bronchospasm. Therefore, it is common to nebulize 3-5 cc of the 10% solution, or dilute the 20% solution to make a 10% solution. It is most common, and very advisable, to co-administer a beta agonist brochodilator with Mucomyst to minimize bronchospastic side effects, although the Mucomyst package insert specifically states this is unnecessary. The most frequently used expectorant, or mucolytic agent is guaifenesin (glyceryl guaiacolate) . Some doctors however do not like ILD patients to use this drug. True mucolytics are drugs intended to control mucus and bronchial secretions. The two primary agents approved for administration as aerosols to treat abnormal pulmonary secretions are acetylcysteine and dornase alfa. Both act to disrupt the disulfide bond in mucus and break down DNA materials in airway secretions. Acetylcysteine (Mucomyst) is an aerosolized medication indicated for treatment of the thick, purulent, viscous mucus secretions that can occur in COPD, especially chronic bronchitis, tuberculosis, cystic fibrosis, and acute tracheobronchitis. It is also administered orally as an antidote to reduce hepatic injury with overdoses of acetaminophen, and is designated as an orphan drug. Aerosol doses of Mucomyst are available in either 10 or 20% solutions, and normal dosage with 20% solution is 3-5 ml TID or QID, and 6-10 ml TID or QID with the 10% solution. The most serious potential side effect is bronchospasm, especially with hyperreactive airways seen in asthmatics, so using bronchodilators mixed with acetylcysteine or administer previously by MDI or nebulizer is recommended. Other potential side effects include stomatitis, nausea, and rhinorrhea. Dornase Alfa (Pulmozyme) is an orphan drug that was produced by recombinant DNA techniques, and is indicated for the treatment and management of the viscid respiratory secretions seen in patients with cystic fibrosis (CF). In CF patients, Pulmozyme helps reduce the frequency of respiratory infections requiring parenteral antibiotics, and generally improves their overall pulmonary function. Pulmozyme available as a single use ampule, with 2.5 mg drug in 2.5 ml of clear solution. Recommended dosage is 2.5 mg daily, delivered by nebulizers specifically approved for this use. Few side effects have been observed, including voice alteration, pharyngitis, laryngitis, rash, chest pain, and conjunctivitis. There are some home remedies that work as mucolytic agents such as spices, garlic, or onion. All these agents work by irritating the lining of the stomach, thereby stimulating the afferent fibers of the vagus nerve. Impulses sent to the CNS elicit an efferent vagal response, stimulating bronchial glands to increase secretion. The secretions moisten and loosen the mucous in the lungs. Been a rough 2 days...woke up yesterday feeling like I could only inhale so much air...there was nowhere to put it once I breathed in. I felt nauseated and tired all day. When I am still, I hear myself panting for air, breathing really fast and shallow. Had to go to WalMart for some meds and realized that when I usually get 2 hrs. on an E tank, I only got an hr and a half yesterday. First time I ever coughed up anything, seemed I felt better after I coughed up this junk. I really am breathing faster, I noticed that first thing. It's not a realaxed breathing. You can imagine how it is with exertion. I was thinking about Vicky's desire for one more Christmas... today I ask for one more Thanksgiving, or for the one more Chat nite with the group. I guess...no, I fear, the end is near. I am suppose to start rehab on the 20th,...lol. My best friend wants me to go to ER ,but I am afraid they will put me on a vent and won't be able to take me off of it. And there I'll be... I am waiting for my new primary Dr. to call with the approval of 750mgs of Levaquuin for a few days. Maybe that will help. I love you all, thank you for allowing me to vent here. So scary, fear grips me and it is such a battle for me....I covet your prayers...and it is such a comfort to know I am not alone. kiss kiss, Ginger 9/04 ipf Sponsored Link Talk more and pay less. Vonage can save you up to $300 a year on your phone bill. Sign up now. 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Guest guest Posted November 10, 2006 Report Share Posted November 10, 2006 RE: . I'm just curious about what the issue is with this drug and our group of lung diseases? Do you know? Me too, I have been taking it for years! Doc's orders. Curious. Joyce >> Carolyn,> > Was wondering.... the information on mucolytics that you provided mentioned that some doctors object to the use of guaifenesin by patients with ILD. Do you know what the objection is? My doctor has actually told me to take Mucinex or the store brand guaifenesin. I'm just curious about what the issue is with this drug and our group of lung diseases? Do you know?> > Beth (Fibrotic NSIP 06/06)> > Draw close. Hold hands. Life is short. God is good.> > > > Re: Breathless> > Dear Ginger: > I dont remember if you said you take a mucolytic agent to thin the mucous secretions so you can cough them up easier and have less difficulty with chest congestion. If not I have included some information below about them. It is important not to take a cough suppressant as that prevents you from coughing up the mucous and the mucous is what attracts bacteria and subsequently infection into the lungs. A mucolytic agent however thins the mucous so the "cilia" (hairs in the bronchial tubes) can pull the secretions up to where they can be coughed out. The thinner the mucous the easier it is for the cilia, or hairs, to pull the mucous up so you can cough it out. I hope some of this information will be of help as it sounds like if you could loosen the mucous so as to cough it up easier you could breathe better. > Hugs,> Carolyn> > > > > > MUCOLYTICS > The high viscosity of sputum in certain respiratory diseases is largely due to the mucoproteins > found in pulmonary secretions. One of the early substances studied was L-cysteine, a naturally > occurring amino acid. The results of L-cysteine were very favorable in terms of its ability to > break the proteinaceous bonds within sputum; however, it had substantial irritating properties. > These irritating properties were minimized by chemically altering the acid into an acetyl form. > The resultant N-acetylcysteine is the generic name of Mucomyst. Within the protein molecules > of sputum, there are two chains of proteins held together with a disulfide bond; that is, both > chains have a sulfur atom such that the two sulfur atoms bind together. Mucomyst breaks up the > chain by replacing the sulfurs with weaker bonds between sulfhydryl molecules. > Mucomyst is available in a 10% and a 20% solution; the 10% is just as effective as the 20% > solution, while the latter exhibits stronger tendencies toward irritation and bronchospasm. > Therefore, it is common to nebulize 3-5 cc of the 10% solution, or dilute the 20% solution to > make a 10% solution. It is most common, and very advisable, to co-administer a beta agonist brochodilator with Mucomyst to minimize bronchospastic side effects, although the Mucomyst package insert specifically states this is unnecessary.> > > > > The most frequently used expectorant, or mucolytic agent is guaifenesin (glyceryl > guaiacolate) . Some doctors however do not like ILD patients to use this drug.> > > > True mucolytics are drugs intended to control mucus and bronchial secretions. The two primary agents approved for administration as aerosols to treat abnormal pulmonary secretions are acetylcysteine and > dornase alfa. > Both act to disrupt the disulfide bond in mucus and break down DNA materials in airway > secretions. > Acetylcysteine (Mucomyst) is an aerosolized medication indicated for treatment of the thick, purulent, viscous mucus secretions that can occur in COPD, especially chronic bronchitis, tuberculosis, cystic fibrosis, and acute tracheobronchitis. It is also administered orally as an antidote to reduce hepatic injury with overdoses of acetaminophen, and is designated as an orphan drug. > Aerosol doses of Mucomyst are available in either 10 or 20% solutions, and normal dosage with 20% solution is 3-5 ml TID or QID, and 6-10 ml TID or QID with the 10% solution. The most serious > potential side effect is bronchospasm, especially with hyperreactive airways seen in asthmatics, so using bronchodilators mixed with acetylcysteine or administer previously by MDI or nebulizer is > recommended. Other potential side effects include stomatitis, nausea, and rhinorrhea. > Dornase Alfa (Pulmozyme) is an orphan drug that was produced by recombinant DNA techniques, and is indicated for the treatment and management of the viscid respiratory secretions seen in patients with cystic fibrosis (CF). In CF patients, Pulmozyme helps reduce the frequency of respiratory infections requiring parenteral antibiotics, and generally improves their overall pulmonary function. > Pulmozyme available as a single use ampule, with 2.5 mg drug in 2.5 ml of clear solution. Recommended dosage is 2.5 mg daily, delivered by nebulizers specifically approved for this use. Few side effects have been observed, including voice alteration, pharyngitis, laryngitis, rash, chest pain, and conjunctivitis.> > > > There are some home remedies that work as mucolytic agents such as > spices, garlic, or onion. All these agents work by irritating the lining of the stomach, thereby > stimulating the afferent fibers of the vagus nerve. Impulses sent to the CNS elicit an efferent > vagal response, stimulating bronchial glands to increase secretion. The secretions moisten and loosen the mucous in the lungs.> > Been a rough 2 days...woke up yesterday feeling like I could only inhale so much air...there was nowhere to put it once I breathed in. I felt nauseated and tired all day. When I am still, I hear myself panting for air, breathing really fast and shallow. Had to go to WalMart for some meds and realized that when I usually get 2 hrs. on an E tank, I only got an hr and a half yesterday. First time I ever coughed up anything, seemed I felt better after I coughed up this junk. I really am breathing faster, I noticed that first thing. It's not a realaxed breathing. You can imagine how it is with exertion.> I was thinking about Vicky's desire for one more Christmas... today I ask for one more Thanksgiving, or for the one more Chat nite with the group. I guess...no, I fear, the end is near. I am suppose to start rehab on the 20th,...lol. My best friend wants me to go to ER ,but I am afraid they will put me on a vent and won't be able to take me off of it. And there I'll be...> I am waiting for my new primary Dr. to call with the approval of 750mgs of Levaquuin for a few days. Maybe that will help.> I love you all, thank you for allowing me to vent here. So scary, fear grips me and it is such a battle for me....I covet your prayers...and it is such a comfort to know I am not alone.> kiss kiss,> Ginger 9/04 ipf> > > > > Sponsored Link > > Talk more and pay less. Vonage can save you up to $300 a year on your phone bill. Sign up now.> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 10, 2006 Report Share Posted November 10, 2006 Hi Carolyn - It's Joanie again. I have been having Bud breathe steam to help with his chronic post-nasal drip. I'm hoping it is helping with eliminating mucus, too. He had raw onions today on his sandwich, and along with several other factors, he has had a pretty good day! Any other natural tips? We are totally open to holistic measures. Thanks - Joanie -- In Breathe-Support , " Carolyn Merritt " wrote: > > Dear Ginger: > I dont remember if you said you take a mucolytic agent to thin the mucous > secretions so you can cough them up easier and have less difficulty with > chest congestion. If not I have included some information below about them. > It is important not to take a cough suppressant as that prevents you from > coughing up the mucous and the mucous is what attracts bacteria and > subsequently infection into the lungs. A mucolytic agent however thins the > mucous so the " cilia " (hairs in the bronchial tubes) can pull the secretions > up to where they can be coughed out. The thinner the mucous the easier it > is for the cilia, or hairs, to pull the mucous up so you can cough it out. > I hope some of this information will be of help as it sounds like if you > could loosen the mucous so as to cough it up easier you could breathe better > > Hugs, > Carolyn > > > > > > MUCOLYTICS > The high viscosity of sputum in certain respiratory diseases is largely due > to the mucoproteins > found in pulmonary secretions. One of the early substances studied was > L-cysteine, a naturally > occurring amino acid. The results of L-cysteine were very favorable in terms > of its ability to > break the proteinaceous bonds within sputum; however, it had substantial > irritating properties. > These irritating properties were minimized by chemically altering the acid > into an acetyl form. > The resultant N-acetylcysteine is the generic name of Mucomyst. Within the > protein molecules > of sputum, there are two chains of proteins held together with a disulfide > bond; that is, both > chains have a sulfur atom such that the two sulfur atoms bind together. > Mucomyst breaks up the > chain by replacing the sulfurs with weaker bonds between sulfhydryl > molecules. > Mucomyst is available in a 10% and a 20% solution; the 10% is just as > effective as the 20% > solution, while the latter exhibits stronger tendencies toward irritation > and bronchospasm. > Therefore, it is common to nebulize 3-5 cc of the 10% solution, or dilute > the 20% solution to > make a 10% solution. It is most common, and very advisable, to > co-administer a beta agonist brochodilator with Mucomyst to minimize > bronchospastic side effects, although the Mucomyst package insert > specifically states this is unnecessary. > > > > > The most frequently used expectorant, or mucolytic agent is guaifenesin > (glyceryl > guaiacolate). Some doctors however do not like ILD patients to use this drug > > > > > True mucolytics are drugs intended to control mucus and bronchial secretions > The two primary agents approved for administration as aerosols to treat > abnormal pulmonary secretions are acetylcysteine and > dornase alfa. > Both act to disrupt the disulfide bond in mucus and break down DNA materials > in airway > secretions. > Acetylcysteine (Mucomyst) is an aerosolized medication indicated for > treatment of the thick, purulent, viscous mucus secretions that can occur in > COPD, especially chronic bronchitis, tuberculosis, cystic fibrosis, and > acute tracheobronchitis. It is also administered orally as an antidote to > reduce hepatic injury with overdoses of acetaminophen, and is designated as > an orphan drug. > Aerosol doses of Mucomyst are available in either 10 or 20% solutions, and > normal dosage with 20% solution is 3-5 ml TID or QID, and 6-10 ml TID or QID > with the 10% solution. The most serious > potential side effect is bronchospasm, especially with hyperreactive airways > seen in asthmatics, so using bronchodilators mixed with acetylcysteine or > administer previously by MDI or nebulizer is > recommended. Other potential side effects include stomatitis, nausea, and > rhinorrhea. > Dornase Alfa (Pulmozyme) is an orphan drug that was produced by recombinant > DNA techniques, and is indicated for the treatment and management of the > viscid respiratory secretions seen in patients with cystic fibrosis (CF). In > CF patients, Pulmozyme helps reduce the frequency of respiratory infections > requiring parenteral antibiotics, and generally improves their overall > pulmonary function. > Pulmozyme available as a single use ampule, with 2.5 mg drug in 2.5 ml of > clear solution. Recommended dosage is 2.5 mg daily, delivered by nebulizers > specifically approved for this use. Few side effects have been observed, > including voice alteration, pharyngitis, laryngitis, rash, chest pain, and > conjunctivitis. > > > > There are some home remedies that work as mucolytic agents such as > spices, garlic, or onion. All these agents work by irritating the lining of > the stomach, thereby > stimulating the afferent fibers of the vagus nerve. Impulses sent to the CNS > elicit an efferent > vagal response, stimulating bronchial glands to increase secretion. The > secretions moisten and loosen the mucous in the lungs. > > Been a rough 2 days...woke up yesterday feeling like I could only inhale > so much air...there was nowhere to put it once I breathed in. I felt > nauseated and tired all day. When I am still, I hear myself panting for air > breathing really fast and shallow. Had to go to WalMart for some meds and > realized that when I usually get 2 hrs. on an E tank, I only got an hr and a > half yesterday. First time I ever coughed up anything, seemed I felt better > after I coughed up this junk. I really am breathing faster, I noticed that > first thing. It's not a realaxed breathing. You can imagine how it is with > exertion. > I was thinking about Vicky's desire for one more Christmas...today I ask > for one more Thanksgiving, or for the one more Chat nite with the group. I > guess...no, I fear, the end is near. I am suppose to start rehab on the 20th > ...lol. My best friend wants me to go to ER ,but I am afraid they will put > me on a vent and won't be able to take me off of it. And there I'll be... > I am waiting for my new primary Dr. to call with the approval of 750mgs > of Levaquuin for a few days. Maybe that will help. > I love you all, thank you for allowing me to vent here. So scary, fear > grips me and it is such a battle for me....I covet your prayers...and it is > such a comfort to know I am not alone. > kiss kiss, > Ginger 9/04 ipf > > > > > Sponsored Link > > Talk more and pay less. Vonage can save you up to $300 a year on your phone > bill. Sign up now. > Quote Link to comment Share on other sites More sharing options...
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