What are NSAIDS

[Guest guest]

Voltaren is an NSAID. An NSAID means Non steroidal anti inflammatory. It's

used mostly for arthritic pain. It's also called Diclofenac. It's used to

relieve the inflammation, swelling, stiffness, and joint pain associated with

rheumatoid arthritis, osteoarthritis and ankylosing spondylitis (arthritis and

stiffness of the spine). Most side effects are to do with the stomach and

bowel.. like most NSAIDS.

Nonsteroidal anti-inflammatory drugs, or NSAIDs (pronounced en-said) are the

most prescribed medications for treating conditions such as arthritis. Most

people are familiar with over-the-counter, nonprescription NSAIDs such as

aspirin and ibuprofen.

NSAIDs are more than just pain relievers. They also help reduce inflammation and

lower fevers. They prevent blood from clotting, which is good in some cases but

not so beneficial in others. For example, because they reduce clotting action,

some NSAIDS, especially aspirin, may have a protective effect against heart

disease. However, you may bruise more easily. NSAIDs can increase the risk of

developing nausea, an upset stomach or an ulcer. They also may interfere with

kidney function.

How they work

NSAIDs work by preventing an enzyme (a protein that triggers changes in the

body) from doing its job. The enzyme is called cyclooxygenase, or COX, and it

has two forms. COX-1 protects the stomach lining from harsh acids and digestive

chemicals; it also helps maintain kidney function. COX-2 is produced when joints

are injured or inflamed.

Traditional NSAIDs block the actions of both COX-1 and COX-2, which is why they

can cause stomach upset and bleeding as well as ease pain and inflammation. Here

are some common traditional NSAIDs:

Treatment applications

NSAIDs are frequently used to treat inflammatory conditions such as arthritis,

bursitis and tendinitis. NSAIDs are relatively inexpensive and are frequently

the first line of medication used to relieve pain and reduce inflammation. Very

low-dose NSAIDs may be prescribed for people with cardiac disease.

COX-2 inhibitors are more expensive than traditional NSAIDs. They are often

prescribed for long-term conditions such as arthritis because they may be safer

for the stomach. However, some studies have not shown any difference between the

incidence of gastrointestinal side effects from traditional NSAIDs and COX-2

inhibitors.

Recent studies have indicated that both NSAIDs and COX-2 inhibitors may have a

delaying effect on bone healing but the extent of this effect is not yet known.

Short-term use of NSAIDs after a fracture or orthopaedic surgery is generally

safe.