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Progesterone metabolites

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Thanks, Virginia. I think the whole area of progesterone and breast is very

interesting. As you know, Vliet has stopped giving patients any P unless it

is needed to protect the endometrium.

It seems that topical progesterone would be a more natural method, except of

course, for those women here who got seriously OD'd on it.

The problem I have with ZRT's recommendation of topical progesterone though

is that, too often, it does not protect the endometrium if women are using

exogenous E. I've posted research to that effect earlier.

Are you aware of any research on this, other than what ZRT is saying?

Val

-----Original Message-----

From: rhythmicliving [mailto:rhythmicliving ]

On Behalf Of Virginia Speaks

Val, the breast-cancer-causing metabolite of progesterone was

mentioned at the conference. The speaker was Jim Paoletti, R.Ph., who

was giving Dr. Zava's lecture, as Dr. Zava was flat in bed with a

back injury. Paoletti stated that ZRT feels that most women balance

the matabolism of P so that those bad metabolites aren't harmful, but

they're watching the research on this. One of the PowerPoint slides

of his lecture says, " Bottom LIne...topical or vaginal progesterone

therapy at physiologic dosing does NOT increase progesterone

metabolites to the same extent as ORAL progesterone therapy. "

[emphasis ZRT].

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