Guest guest Posted April 21, 2008 Report Share Posted April 21, 2008 Thanks, Virginia. I think the whole area of progesterone and breast is very interesting. As you know, Vliet has stopped giving patients any P unless it is needed to protect the endometrium. It seems that topical progesterone would be a more natural method, except of course, for those women here who got seriously OD'd on it. The problem I have with ZRT's recommendation of topical progesterone though is that, too often, it does not protect the endometrium if women are using exogenous E. I've posted research to that effect earlier. Are you aware of any research on this, other than what ZRT is saying? Val -----Original Message----- From: rhythmicliving [mailto:rhythmicliving ] On Behalf Of Virginia Speaks Val, the breast-cancer-causing metabolite of progesterone was mentioned at the conference. The speaker was Jim Paoletti, R.Ph., who was giving Dr. Zava's lecture, as Dr. Zava was flat in bed with a back injury. Paoletti stated that ZRT feels that most women balance the matabolism of P so that those bad metabolites aren't harmful, but they're watching the research on this. One of the PowerPoint slides of his lecture says, " Bottom LIne...topical or vaginal progesterone therapy at physiologic dosing does NOT increase progesterone metabolites to the same extent as ORAL progesterone therapy. " [emphasis ZRT]. Quote Link to comment Share on other sites More sharing options...
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