Guest guest Posted March 15, 2000 Report Share Posted March 15, 2000 Here is a post from Kusic Marta to LC-DIABETES regarding the prescribing of NPH insulin ... **************** The answer to your question [why doctors prescribe NPH rather than ultralente] is: " Because they are ill informed. " In all Bernstein's books he points to the drawback of NPH: 1. It produces more antibodies than R and L and UL insulins. These bind the insulin molecules and release them at unpredictable time, making it hard to predict the action of the insulin. 2. If you have heart surgery, often the doctor administers Heparin at the end of the operation (I forgot why). This can cause allergic reaction for people consuming NPH that can even kill you. 3. The duration of NPH action is too short to serve as a basal overnight. Let me add that Dr. Bernstein recommends to split UL in two portions to be taken in the morning and evening. My Doctor in Jerusalem swears that this is a grave mistake, but he is wrong: An excellent study of Ron Sebol (posted here) shows that for an average diabetic, splitting the dose yield a smooth curve so that UL can serve in a way similar to the basal that is used by pump users. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 16, 2000 Report Share Posted March 16, 2000 Bernstein (p. 226) recommends no more than 7 units of insulin at any one time, in one location. (He discusses fine-tuning insulin doses beginning on page 222.) I think every diabetic - especially those using insulin - should consult Bernstein. Susie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 16, 2000 Report Share Posted March 16, 2000 Thanks, Susie. That would be for me, due to physical activity in the daytime. I appreciate all the references on this subject, and if I could just figure out what the heck Ron Sebol is actually saying half the time... I do have some of his relevant posts saved, thanks to you all sharing them. Barb -------------- RAINBOW FARM UNLTD. Breeding Premium Oldenburgs, and fancy sport ponies. http://www.rainbowfarm.com > > >In the LC-D archives, Ron Sebol mentions that the daytime U dose can be as >little as 40% of the nighttime dose. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 16, 2000 Report Share Posted March 16, 2000 > > > Bernstein (p. 226) recommends no more than 7 units of insulin at any one > time, in one location. (He discusses fine-tuning insulin doses beginning on > page 222.) I think every diabetic - especially those using insulin - should > consult Bernstein. I usually take a minimum of 7 units of insulin per meal. With 4 injections per day, and minimum 5 finger sticks per day, that's already 9 ... and then add another 3 for splitting the dose... that's 12! ... heeerre's ... the human pincussion Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 17, 2000 Report Share Posted March 17, 2000 In a message dated 00-03-16 21:12:12 EST, you write: << I usually take a minimum of 7 units of insulin per meal. With 4 injections per day, and minimum 5 finger sticks per day, that's already 9 ... and then add another 3 for splitting the dose... that's 12! ... heeerre's ... the human pincussion >> I assume you're talking about 7 units Humalog per meal? I'm not trying to one-up you, , but my regime of one shot per meal plus background a.m. and bedtime background insulin...and I generally do eight fingerstix a day...I'm more of a pincushion than you... I'm downright full of holes! :-) Susie, I reviewed my Bernstein but I don't know how to equate it to my situation since I don't take R at all. I think I'll probably just start low, maybe at 4 units UL a.m. and bedtime and see how it goes. My three-month doc appointment is next Wednesday...hoping A1C is lower than past two times of 6.3...I was doing pretty good until this darned cold hit...knocked my averages to heck and gone for the past week. And you know, A1C gives more weight to recent BGs...also my low back went out the other day and every time I cough it really hurts a lot...I feel like a little old lady this week...Vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 17, 2000 Report Share Posted March 17, 2000 Oh Vicki, I'm so sorry you aren't feeling well. I've also been having a problem with my back but I've had back surgery and have a permanently damaged sciatic nerve which affects my left leg. It hurts so bad sometimes (like now) that I can hardly stand anything to touch it, even to cover with a sheet. I really do understand and hope you're feeling much better real soon. Love you, Tootie Re: NPH vs. UL or L insulin From: whimsy2@... In a message dated 00-03-16 21:12:12 EST, you write: << I usually take a minimum of 7 units of insulin per meal. With 4 injections per day, and minimum 5 finger sticks per day, that's already 9 ... and then add another 3 for splitting the dose... that's 12! ... heeerre's ... the human pincussion >> I assume you're talking about 7 units Humalog per meal? I'm not trying to one-up you, , but my regime of one shot per meal plus background a.m. and bedtime background insulin...and I generally do eight fingerstix a day...I'm more of a pincushion than you... I'm downright full of holes! :-) Susie, I reviewed my Bernstein but I don't know how to equate it to my situation since I don't take R at all. I think I'll probably just start low, maybe at 4 units UL a.m. and bedtime and see how it goes. My three-month doc appointment is next Wednesday...hoping A1C is lower than past two times of 6.3...I was doing pretty good until this darned cold hit...knocked my averages to heck and gone for the past week. And you know, A1C gives more weight to recent BGs...also my low back went out the other day and every time I cough it really hurts a lot...I feel like a little old lady this week...Vicki ------------------------------------------------------------------------ DON'T HATE YOUR RATE! Get a NextCard Visa, in 30 seconds! Get rates as low as 0.0% Intro or 9.9% Fixed APR and no hidden fees. Apply NOW! http://click./1/2120/1/_/529507/_/953314438/ ------------------------------------------------------------------------ Public website for Diabetes International: http://www.msteri.com/diabetes/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 17, 2000 Report Share Posted March 17, 2000 Vicki, I started U last night, and, since Susie said Ron said <vbg> less U than N, I started with 2/3 U than I used to take N at night. This morning my fbg was 156, so I'll up it 2 units tonight. Same thing with my am dose of U - 2/3 less than the N previously, and my lunchtime bg was much higher too. So I'll keep working on it. I do think it's a good idea to start lower, though. I'd rather have a high reading than die from a hypo for sure! Barb -------------- RAINBOW FARM UNLTD. Breeding Premium Oldenburgs, and fancy sport ponies. http://www.rainbowfarm.com Re: NPH vs. UL or L insulin >From: whimsy2@... > >In a message dated 00-03-16 21:12:12 EST, you write: > ><< > I usually take a minimum of 7 units of insulin per meal. With 4 injections >per > day, and minimum 5 finger sticks per day, that's already 9 ... and then add > another 3 for splitting the dose... that's 12! ... heeerre's ... the >human > pincussion > > >> > >I assume you're talking about 7 units Humalog per meal? >I'm not trying to one-up you, , but my regime of one shot per meal plus >background a.m. and bedtime background insulin...and I generally do eight >fingerstix a day...I'm more of a pincushion than you... I'm downright full of >holes! :-) > >Susie, I reviewed my Bernstein but I don't know how to equate it to my >situation since I don't take R at all. I think I'll probably just start low, >maybe at 4 units UL a.m. and bedtime and see how it goes. My three-month doc >appointment is next Wednesday...hoping A1C is lower than past two times of >6.3...I was doing pretty good until this darned cold hit...knocked my >averages to heck and gone for the past week. And you know, A1C gives more >weight to recent BGs...also my low back went out the other day and every time >I cough it really hurts a lot...I feel like a little old lady this >week...Vicki > >------------------------------------------------------------------------ >DON'T HATE YOUR RATE! >Get a NextCard Visa, in 30 seconds! Get rates as low as >0.0% Intro or 9.9% Fixed APR and no hidden fees. >Apply NOW! >http://click./1/2120/1/_/529507/_/953314438/ >------------------------------------------------------------------------ > >Public website for Diabetes International: >http://www.msteri.com/diabetes/ > > > Quote Link to comment Share on other sites More sharing options...
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