Urso Side Effects

[Guest guest]

I appreciate all that everyone writes re: PSC, their symptoms, meds,

etc. I have learned so much and I am so grateful to find PSC-support

group. My heart and prayers go out to Ed and Debbie and their

families during these days after their surgeries. I pray for all

those that are connected with this support group. I wish I would

have known about PSC-support groups years ago. I am thankful I

finally found this great group of individuals.

My gastro. dr. put me on Urso last week and I was wondering if anyone

can tell me how long the abdominal pain, etc. lasts? Do the side

effects of this drug go away after your system gets adjusted to it?

History:

Gallbladder surgery, liver biopsy-1973

Bile duct surgery-76 (connected the bile duct to the jejunum(sp?)

2nd liver biopsy-80 (diagnosed chronic hepatitis)

ERCP, liver biopsy-82 (PSC diagnosis)Methodist Hospital-Indiana, Dr.

McCune, neg. for UC, or Chrohns.

2nd opinion, ERCP, liver biopsy, etc.-83 (Emory Hosp., Dr. Galambos)

confirmed PSC, neg. for UC, or Chrohns.

Bile duct-4 large stones, surgery-90-Methotrexate prescribed, IV

steroids.

1st TX workup - Emory-Dr. Galambos-91-cholestraymine prescribed.

2nd TX workup - MUSC-ton-95-Actigall presribed.

1996-Saw a gastroenterologist here in Spartanburg and he doubts I

have PSC., I hope he is right, after another ERCP he confirms I DO

have it.

Symptoms have been sporadic over last 6 years, 2000-lost 15 lbs,

itching, nausea, etc, infection in

ducts, antibiotic regiment, Colestid prescribed.

Itching, fatigue, URQ pain returns, gastro prescribes URSO-2001.

I have never been jaundice. I am now 47, this all began when I was

19.

I believe I alot of my URQ pain is from previous surgeries and

adhesions. I may be wrong.

Thanks for being there.

Pam-SC

[Guest guest]

Pam,

As for the pain after taking Urso, I started taking 750 mg at first

(switched from Actigall to Urso in 3/01) and never experienced any pain or

nausea. When I went to 1,500 a day (6/01), I did not experience any pain

or discomfort. My nausea only started in the last month or so.

I have always been very tolerant of drugs, no matter what it was.

Glad you found the group, I am new as well (3 weeks and counting). They (

we? :-) ) are a wonderful group of people who can sympathize with what

you are going through and are a wealth of information. I have been

printing out a lot of emails and making my own checklist for when I go back

to see the Hep. We often take what dr tell us without being educated and

this group will give the resources to ask the right questions and to ease

your concerns.

Best wishes.

Darin

Houston, UC-88, PSC-99 (age 32)