Fasciculations, albumin and creatinine

September 28, 2001

Yesterday I got the results of my blood tests. All of my liver

enzymes were lower than last time, although they were still

noticeably elevated. However, my serum creatinine levels were also

elevated (they were normal 3 months ago), and my doc wanted to check

them again after two weeks. Now I understand that creatinine might be

an indication of early renal failure, but how common are elevated

creatinine levels in PSC? FYI, I also have the following diseases

Type 1 Diabetes (since 1979)

Celiac disease (since 1984)

UC (2001)

PSC (2001)

I would guess that the creatinine elevations might be a complication

of my Diabetes, but who knows what the interactions between these

diseases are?

Also, my serum albumin levels were a bit low. How common is this in

the early stages of PSC? My doctor said that it can sometimes take up

to a year before the albumin levels get back to normal, even though I

can't quite understand what he meant. Normalize from what? After all,

shouldn't PSC be a progressive disease?

And to my final question: Has anyone else noticed that whenever their

liver enzymes are up, they get fasciculations (muscle twitches) all

over their body, most notably in their legs and calves? They are not

cramps, but small twitches that can even go unnoticed. The only thing

I'm sure of is that there is a clear correlation between these

twiches and my liver enzymes. Whenever my enzyme activity is high, it

look like there are worms crawling under my skin. It shouldn't really

be any neurological disease (like ALS) since I've had it for over a

year and it is in someway linked to my liver. Any expert opinions?

September 28, 2001

Oh yes, and this post was from me, . Just forgot to put my

name in it...

> Yesterday I got the results of my blood tests. All of my liver

> enzymes were lower than last time, although they were still

> noticeably elevated. However, my serum creatinine levels were also

> elevated (they were normal 3 months ago), and my doc wanted to

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