Re: Fw: FDA MedWatch - Topamax (topiramate) associated with hyperchloremi c, non-anion gap metabolic acidosis

[Guest guest]

Brande,

Thanks for posting this. I was taking topamax, got off of it when I

got pregnant. I was hoping to go back on it to get this pain under

control again (it has been way out of control since the baby

came!). I'm going to have to look into this more! Thanks a bunch!

> If I am not mistaken, I believe some of you have used Topamax, so

I thought

> you might be interested in this.

>

> Me

> Nebraska, USA

> mymocha@c...

>

>

>

> > MedWatch - The FDA Safety Information and Adverse Event

Reporting Program

> >

> > Ortho-McNeil and FDA revised the WARNINGS and PRECAUTIONS

sections of the

> > prescribing information, notifying healthcare professionals that

Topamax

> > causes hyperchloremic, non-anion gap metabolic acidosis

(decreased serum

> > bicarbonate). Measurement of baseline and periodic serum

bicarbonate

> during

> > topiramate treatment is recommended.

> >

> > Read the 2003 Medwatch safety summary, including links to

the " Dear

> > Healthcare Professional " letter and revised label, at:

> >

> > http://www.fda.gov/medwatch/SAFETY/2003/safety03.htm#topamax2

> >

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