Glucophage XR and Avandia

[Guest guest]

My endo switched me on April 20, 2001 from taking one tablet of 850mg

glucophage with meals in addition to 0.5mg prandin with dinner to 4 tablets

of 500mg Glucophage XR and one 4mg Avandia per day. Bg's running extremely

high 200's, 300's. If I'm lucky, mid 100's whereas before the switch, rarely

hit 200 and dinner post prandials in normal range(latest A1C - 6.4). My endo

said to give avandia a little more time to work. Usually takes a month or

more for your system to adjust.

Anybody else on glucophage XR with or without avandia? Are your bg's running

higher than before? Or if this is your first regimen, how are your bg's?

Somehow, it doesn't seem right. Exercise and weight is not an issue. I'm a

road cyclist and I ride everyday at lunch time, hard and fast. Also, when in

season, I referee basketball games several times a week, two or three games

per assignment.

Due to insurance coverages, I had to switch endo's last year. Previous endo

started my on the 850's and prandin. She said at that time that I didn't

need avandia since my cells were already sensitized from all the exercise I

do. However, my current endo wanted me to try (I guess for convenience) the

once a day XR with avandia. I'll suggest to her to keep me on XR but instead

of avandia, put me back on prandin.

Any thougts group?

I just left her a message and faxed over my latest bg's. I'll keep everyone

posted.

Steve

NYC, Type II

[Guest guest]

> Anybody else on glucophage XR with or without avandia? Are your bg's

running higher than before? Or if this is your first regimen, how are

your bg's?

I'm on 500mg of Glucophage XR per day (by itself). My fasting bg's are

100-120, 2-hr postmeal bg's are 100-130. I was diagnosed in late March

and started taking G XR on 4/18/01; was on Glucovance for 2 weeks

before that; so I don't have much past history to compare.

G XR is doing the job for me. At diagnosis, my bg's were above 300,

and HbA1C was 12.2.

H. Pham

[Guest guest]

Steve, I take G XR and Avandia. I was staying high like that so my DR

added one 2 mg dose of Amaryl in the AM. I've been in the normal

range ever since about 2 weeks ago. As a matter of fact, I had my

first low today. I was 95 before exercise, and ate two sugar wafer

cookies. Went to the fitness center and dropped to 58 post exercise.

I thought the cookies would raise me enough so I wouldn't drop too

bad. I didn't seem to have any symptoms I was going low. Ate 3

glucose tabs and called my husband to come get me and my daughter. We

then went to lunch and I ate Mexican. Two cheese enchiladas, side of

beans, and one forkful of rice, a diet coke. I was 95 an hour ago so

I had a snack. I'm watching things. I feel really good and my dr is

happy with my numbers, and I can eat in a way I don't feel so

deprived. But I'm going to watch the lows, I might have to have the

meds lowered if I keep getting a lot of lows. So maybe the Avandia

kicked in finally, or the amaryl is helping, or both. Do what you

feel is best for you and approach your dr about it.

Debbie in Utah

> My endo switched me on April 20, 2001 from taking one tablet of

850mg

> glucophage with meals in addition to 0.5mg prandin with dinner to 4

tablets

> of 500mg Glucophage XR and one 4mg Avandia per day. Bg's running

extremely

> high 200's, 300's. If I'm lucky, mid 100's whereas before the

switch, rarely

> hit 200 and dinner post prandials in normal range(latest A1C -

6.4). My endo

> said to give avandia a little more time to work. Usually takes a

month or

> more for your system to adjust.

>

> Anybody else on glucophage XR with or without avandia? Are your

bg's running

> higher than before? Or if this is your first regimen, how are your

bg's?

>

> Somehow, it doesn't seem right. Exercise and weight is not an

issue. I'm a

> road cyclist and I ride everyday at lunch time, hard and fast.

Also, when in

> season, I referee basketball games several times a week, two or

three games

> per assignment.

>

> Due to insurance coverages, I had to switch endo's last year.

Previous endo

> started my on the 850's and prandin. She said at that time that I

didn't

> need avandia since my cells were already sensitized from all the

exercise I

> do. However, my current endo wanted me to try (I guess for

convenience) the

> once a day XR with avandia. I'll suggest to her to keep me on XR

but instead

> of avandia, put me back on prandin.

>

> Any thougts group?

>

> I just left her a message and faxed over my latest bg's. I'll keep

everyone

> posted.

>

> Steve

> NYC, Type II