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Hi Malcolm,

I had horrible insomnia in the last year before my tx. It drove me

crazy. Sometimes it was just that I couldn't switch off my thoughts

enough to allow myself to go to sleep. Sometimes it was due to the

drenching night sweats I was experiencing. Sometimes it was the itching

that we get due to deposition of bile salts in our skin. It was very

frustrating and worsened the fatigue that I was living with during that

time.

My Hepatologist gave me a prescription for Oxazepam (Serax) 10 mg. I

asked for this low dose, the usual dose used in Geriatric patients

because of my previous experiences with sedatives. I tried not to use

this medication every night as it can be habit forming. I found that

when I used it I had some residual problems the next morning; I felt

like I was in a bit of a fog.

A friend gave me some Melatonin to try. I asked my Hepatologist before

using it and she approved it. The few times I used it, it seemed to help

without the foggy feeling the next morning.

You should check with your physician and discuss the situation with that

person before trying any new drug or treatment. Apparently insomnia in

people with liver disease is quite common.

Aubrey Goldstein, MD

Liver tx, May/98

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