Guest guest Posted December 13, 2000 Report Share Posted December 13, 2000 Hi Everyone, Here is some interesting info on muscle cramps which relates to liver disease. This last year I started waking up in the middle of the night with a cramp in the arch of my foot. I started doing some stretching excercises for my legs and feet and that seems to have helped a lot. - D. subj: Muscle cramps and liver disease http://www.healthmall.com/medline.html BACKGROUND: While not life threatening, muscle cramps severely affect the quality of life of patients with cirrhosis. AIM: To determine whether oral zinc sulfate therapy decreases the frequency and severity of muscle cramps in cirrhotic patients. METHODS: 12 patients with cirrhosis (5 Child's A, 3 Child's B, and 4 Child's C), hypozincemia and muscle cramps at least thrice weekly received oral zinc sulfate 220 mg BID for 12 weeks. Patients answered a questionnaire regarding their muscle cramps symptoms at the beginning and end of the study. RESULTS: Muscle cramps occurred in all patients at rest, mainly while sleeping (8/12), and in two patients also during exercise. Cramps were located in calves (10/12), feet (4/12) and hands (4/12) more commonly. Zinc supplementation improved cramps in 10/12 patients, and in seve>>>> EXCERPT>>>>>>> CONCLUSION: A potential relationship between zinc deficiency and muscle cramps in the setting of cirrhosis has not been suggested before. Zinc supplementation may lead to improvement in symptoms associated with muscle cramps in cirrhosis. Muscle cramps are a common complaint in clinical practice. They are associated with various metabolic, endocrine, neurological and electrolyte abnormalities. A variety of hypotheses have been generated to explain the cause of muscle cramping, yet none has been able to support a consistent pathophysiological mechanism. Muscle cramps are painful, involuntary contractions of skeletal muscle. They occur frequently in individuals with cirrhosis, regardless of the etiology, and are thought to be a symptom of cirrhotic-stage liver disease. The pathophysiology of these cramps remains elusive; hence, a specific therapy has not been identified. Many therapeutic approaches have been offered, yet their efficacy, safety and mechanism of action remain poorly defined. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2000 Report Share Posted December 14, 2000 I have also been having trouble with cramps for several years now. For me, it has become the first indicator that I am becoming dehydrated. At the onset of the first cramp (usually in the arch of one of my feet) I go and drink as much water as I can reasonably handle. In every case (literally every case) this has solved the problem. I have noticed that the degree to which I am dehydrated is directly proportional to the length of time it takes after I drink the water for the cramps to subside. Sometimes only a minute or two and sometimes 10 to 20 minutes. B tx x2 Colorado Springs Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 16, 2000 Report Share Posted December 16, 2000 Something I found helpful for foot cramps is tonic water. The quinine in it helps I usually mix it with cranberry juice and take care of two problems at once (cranberry juice being good for the bladder). At one point I put a banana in the blender with cranberry juice and then added tonic water, hmmmm a smoothie. Yum Peg Quote Link to comment Share on other sites More sharing options...
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