Re: Glutathione: Duncan

[Guest guest]

A glutathione question...I gave my son transdermal glutathione, and he became

so hyperactive it was as though his body were shimmering when I held him. My

DAN doctor suggested it was possibly because of a carrying agent and not the

glutathione itself. Now that Kirkman's has a transdermal glutathione, he has

suggested I try again. My son's reaction to the first brand was so extreme

I'm afraid to try the Kirkman's.

Do you suspect glutathione could cause this reaction, or is a carrying agent

a more likely suspect? If glutathione, why?

What would determine if a child needs to be given glutathione? Any specific

markers in blood, urine, hair or stool tests? Any specific physical or mental

characteristics? Anything else? So much of what my son is getting or has been

suggested that he gets I feel is like throwing darts, and I'm really trying

to avoid that as best I can.

Thanks for any suggestions,

Debbie

[Guest guest]

Hi Carolyn;

> an emergency situation such as to increase liver glutathione in the

> event of acetaminophen overdose. In addition, NAC-induced

glutathione

> levels often fall to below original levels as the drug is withdrawn.

I have been giving her N-Acetyle Cysteine (NAC) during the off days

of the chelation cycle (days 1-11). She gets 100 mg in the morning

and in the evening. Now I'm really concerned about this! Your

comments?

NAC has an absolute life of 4 hours, half-life of two hours. When

glutathione drops there is more free radical damage throughout the system

due to oxidative stress, and less resistance to disease and infection. I

can't comment on NAC dosage but I have seen studies in which the higher

doses exacerbate mercury symptoms.

Seems the doctors are HOPING normal glutathione levels will be there, which

they probably aren't because of the toxins. Also, if they were, there would

have been less toxic buildup to begin with. They can check those levels on

day 2 and 13, for example.

Even healthy athletes can boost their cellular glutathione levels up to 30%.

I think the taurine is linked to the cycle other main liver amino

methionine. I've lent out my book...sorry. Glycine's fine but depending on

her diet may not really be necessary.

Lipoic acid, Vitamin C, and cilantro are also chelators. In the brain, the

glutathione's pretty good and is natural.

The DMSA is good and fast for the bulk of it and the Immunocal will mop up

by increasing glutathione levels for about a 30 hour half-life.

ciao

Duncan

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[Guest guest]

Duncan,

My son is sufffering from one infection after another, he is on many

supplements and a GF/Cf diet but is sick every week, how can I best

boost his ammune system? He is also takeing collostrum and probiotics

as well as enzymes, he also has a yeast problem from all the

antibiotics used to treat his cronic sinus infections. He is also

becoming increasingly hyper. Thanks for you help!!

Jill

> Hi Carolyn;

>

> > an emergency situation such as to increase liver glutathione in

the

> > event of acetaminophen overdose. In addition, NAC-induced

> glutathione

> > levels often fall to below original levels as the drug is

withdrawn.

> I have been giving her N-Acetyle Cysteine (NAC) during the off days

> of the chelation cycle (days 1-11). She gets 100 mg in the morning

> and in the evening. Now I'm really concerned about this! Your

> comments?

>

> NAC has an absolute life of 4 hours, half-life of two hours. When

> glutathione drops there is more free radical damage throughout the

system

> due to oxidative stress, and less resistance to disease and

infection. I

> can't comment on NAC dosage but I have seen studies in which the

higher

> doses exacerbate mercury symptoms.

>

> Seems the doctors are HOPING normal glutathione levels will be

there, which

> they probably aren't because of the toxins. Also, if they were,

there would

> have been less toxic buildup to begin with. They can check those

levels on

> day 2 and 13, for example.

>

> Even healthy athletes can boost their cellular glutathione levels up

to 30%.

>

> I think the taurine is linked to the cycle other main liver amino

> methionine. I've lent out my book...sorry. Glycine's fine but

depending on

> her diet may not really be necessary.

>

> Lipoic acid, Vitamin C, and cilantro are also chelators. In the

brain, the

> glutathione's pretty good and is natural.

>

> The DMSA is good and fast for the bulk of it and the Immunocal will

mop up

> by increasing glutathione levels for about a 30 hour half-life.

>

> ciao

>

> Duncan

>

>

>

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> Checked by AVG anti-virus system (http://www.grisoft.com).

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[Guest guest]

Hi Jill;

Glutathione is the body's main antioxidant. It is created in every cell of

the body provided there are raw materials in sufficient quantity.

People with high glutathione levels are better able to chelate, detox, repel

infections of all types, and quench free radical cascades.

Glutathione recycles the other antioxidants vitamin C, E, and lipoic acid.

Although a few drugs have been around for a long time to increase cellular

glutathione levels, their effects are very marginal. Now we all have

something that works well. Like the FDA says on their website, the best way

to increase cellular glutathione is giving undenatured whey isolate for the

raw materials: (Immunocal is the ONLY whey isolate officially approved by

the FDA)

http://www.fda.gov/ohrms/dockets/ac/00/slides/3652s1_05/sld001.htm

Many many experiments have been done on this subject. Immunocal is patented

for reducing HIV viral load, and also for shrinking tumours. In fact the US

Physician's Desk Reference states that is what it's useful for.

But in addition to that we have such a broad range of positive effects that

if the populace generally was familiar with it we'd have only 1/4 of the

medical load our society has today.

Glutathione is well-covered in the Medline literature on any subject from

metal detox through neural degeneration, dibetes, cholesterol, IBD, cancer,

infections and Chrohn's. Practically every disease and especially every

age-related disease is linked strongly to low cellular glutathione levels.

Glutathione is becoming a well-known word like 'vitamin' or 'cholesterol'

because of its importance. If a person had to select only ONE supplement,

that should be Immunocal.

In the context of this list, this is the link that was missing in the

treatments of your children. Of course it's not likely to reverse mechanical

damage on its own, but because children tend to do that through natural

healing, getting them to the point at which they will heal UNIMPEDED will

bring the best results.

I have several fairly PDF documents here for anybody who wants them, and I'd

be happy to help by answering any detailed questions. You may contact me by

private email.

There are also several points I haven't touched on like digestion/ bowel

health/ gall bladder and liver flush that are of course very important to

everyone's health. Is this too far off the topic?

best regards,

Duncan

duncancrow at shaw dot ca

___________________________________________________________

Increase your antioxidant protection, immune system, detoxification

by increasing cellular glutathione. Immunocal is supported by the FDA and

is listed in the Physician's Desk Reference and Pharmacist's Red Book.

Call 1888-830-4040 for FREE in-depth messages and Dr.'s testimonials.

Call 1888-462-3397 and use ID#57023 to get Immunocal for 40% off.

www.immunotec.com

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[Guest guest]

Hi Debbie;

Because glutathione can NOT produce side effects, I'd suspect either the

carrying agent like the doctor says, or perhaps the lad was sensitive to the

quick toxin release due to its effects as a chelator/germicide. Usually the

fist symptom of any kind toxicity in children is hyperactivity.

Blood and tissue glutathione levels are known to be low in both toxification

and in chronic disease. Tissue levels are particularly low at and near the

site of the insult. Blood levels can be easily checked.

When taking the glutathione precursor Immunocal (HMS-90 in Canada), even

healthy athletes can raise these levels up to 30%; after hitting the max,

the self-limiting factor does not allow further increase.

Not to say that the self-limiting works at all with injected glutathione.

Taking Immunocal isn't at all like throwing darts. It's almost a panacea.

Once you see the broad range of positive effects there'll be only a couple

of things to tune up.

Balancing pH with clacium and magnesium, vitamins, and using trace minerals

are important. Bowel health/cleansing too.

best regards,

Duncan Crow

duncancrow at shaw dot ca

<<A glutathione question...I gave my son transdermal glutathione, and he

became

so hyperactive it was as though his body were shimmering when I held him. My

DAN doctor suggested it was possibly because of a carrying agent and not the

glutathione itself. Now that Kirkman's has a transdermal glutathione, he has

suggested I try again. My son's reaction to the first brand was so extreme

I'm afraid to try the Kirkman's.

Do you suspect glutathione could cause this reaction, or is a carrying agent

a more likely suspect? If glutathione, why?

What would determine if a child needs to be given glutathione? Any specific

markers in blood, urine, hair or stool tests? Any specific physical or

mental

characteristics? Anything else? So much of what my son is getting or has

been

suggested that he gets I feel is like throwing darts, and I'm really trying

to avoid that as best I can.>>

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[Guest guest]

I came late to this discussion so this may have been asked already. But

why take a glutathione precursor (Immunocal)? Why not just take the

glutathione itself? I know it is available in capsules from a number of

companies.

in FL

[Guest guest]

Hi Setven;

Glutathione oral supplements break down in the gut and are digested as any

other protein. Studies have shown that this supplementation does not raise

cellular glutathione levels materially.

Injecting glutathione has marginal effect of raising cellular glutathione,

the levels increase mainly in the blood stream.

Cellular glutathione must be created within each cell. For that you need a

precursor, not a direct supplement.

Cysteine, a precursor, has known toxicity, and it doesn't increase cellular

glutathione when taken orally. Mainly, it breaks down in the gut, enters

the blood stream with difficulty, and fails the main task.

But the dipeptide cystine (note spelling) is directly absorbed through the

lumen, enters the cells readily, and donates 2 cysteines at that point. As

the FDA points out, an undenatured whey isolate is the best way to raise

cellular glutathione levels. Immunocal is the whey isolate the FDA tested.

This is exactly what Immunocal is designed to do. It was originally supposed

to be marketed as a drug, but could not be synthesized.

NAC does enter the bloodstream and the cells and raise cell glutathione but

also exhibits toxic side effects. In addition, it's half-life is two hours

in the body, so 7 to 10 doses are needed daily to keep levels high.

Otherwise glutathione levels crash, often to below original levels. NAC is

most useful in emergency situations like bailing out the liver during

treatment for an overdose of acetominophen, which releases large amounts of

free radicals.

Lastly, we are short minerals in our diet especially in North America, and

in this case we are almost all deficient in selenium, a mineral that is key

to making the glutathione tri-peptide.

ciao

Duncan

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