Guest guest Posted October 25, 2001 Report Share Posted October 25, 2001 Cheryl, Just making sure you understand that Creon is a whole different ball game from the plant based enzymes. If you are trying to help with the gluten intolerance, you may want to consider changing to one of the plant based enzymes which break down the gluten in the stomach, thereby preventing any peptides. Here are some comments by Devin Houston from previous posts on Creon vs. plant derived enzymes: Creon, or Kreon, is an enteric-coated prescription formula of pancreatic enzymes. Creon is a pharmaceutical-grade extract preparation of pancreatic enzymes derived from pig or cow pancreas. Creon has been used for decades mostly for cystic fibrosis patients and those with pancreatic insufficiency. It is enteric-coated because pancreatic enzymes are pH-sensitive (pH range of 6.5 to 8.5) and are rapidly inactivated by stomach acid. To overcome this, they are coated such that the enzymes are not released until well into the small intestine. The problem with enteric-coating is it adds expense to a product, and release of the active drug can be variable and inconsistent. Methyl acrylate is used in the coating process, I don't particularly care for that chemical in my system, thank you. The problem with the enzymes not being released until in the intestine defeats the purpose of taking enzymes for peptide elimination. Once the casein and gluten are in the gut, any peptides produced will be absorbed quickly. Plant enzymes work in the stomach, so the protein breakdown process starts sooner (peptides aren't absorbed in the stomach) so less chance of peptides escaping. Creon is predominantly lipase, with protease and amylase activities. It is used to treat steatorrhea (fat in poop), breaking down fats so they are absorbed rather than excreted. Plant enzymes are more separated in their activities, so one can customize the particular enzyme combination to affect proteins, complex carbs, or triglycerides. Creon usually requires a prescription, plant enzymes are sold as dietary supplements and do not require a doctor's script. Creon has been shown to help some autists, thus indicating that any enzyme product may be helpful to a subset of individuals. Plant enzyme products derived from papaya, pineapple or cultivated Aspergillus niger/oryzae organisms. Plant enzymes are naturally stable to acid, with a working pH range of 2.5 to 9, depending on the particular enzyme. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 25, 2001 Report Share Posted October 25, 2001 ckelley100, Thank you for the info. I'm thinking about trying the plant based enzymes. Cheryl > Cheryl, > > Just making sure you understand that Creon is a whole different ball > game from the plant based enzymes. If you are trying to help with > the gluten intolerance, you may want to consider changing to one of > the plant based enzymes which break down the gluten in the stomach, > thereby preventing any peptides. Here are some comments by Devin > Houston from previous posts on Creon vs. plant derived enzymes: > > Creon, or Kreon, is an enteric-coated prescription formula of > pancreatic enzymes. Creon is a pharmaceutical-grade extract > preparation of pancreatic enzymes derived from pig or cow pancreas. > Creon has been used for decades mostly for cystic fibrosis patients > and those with pancreatic insufficiency. It is enteric-coated because > pancreatic enzymes are pH-sensitive (pH range of 6.5 to 8.5) and are > rapidly inactivated by stomach acid. To overcome this, they are > coated such that the enzymes are not released until well into the > small intestine. The problem with enteric-coating is it adds expense > to a product, and release of the active drug can be variable and > inconsistent. Methyl acrylate is used in the coating process, I don't > particularly care for that chemical in my system, thank you. > > The problem with the enzymes not being released until in the > intestine defeats the purpose of taking enzymes for peptide > elimination. Once the casein and gluten are in the gut, any peptides > produced will be absorbed quickly. Plant enzymes work in the stomach, > so the protein breakdown process starts sooner (peptides aren't > absorbed in the stomach) so less chance of peptides escaping. > > Creon is predominantly lipase, with protease and amylase activities. > It is used to treat steatorrhea (fat in poop), breaking down fats so > they are absorbed rather than excreted. Plant enzymes are more > separated in their activities, so one can customize the particular > enzyme combination to affect proteins, complex carbs, or > triglycerides. Creon usually requires a prescription, plant enzymes > are sold as dietary supplements and do not require a doctor's script. > Creon has been shown to help some autists, thus indicating that any > enzyme product may be helpful to a subset of individuals. Plant > enzyme products derived from papaya, pineapple or cultivated > Aspergillus niger/oryzae organisms. Plant enzymes are naturally > stable to acid, with a working pH range of 2.5 to 9, depending on the > particular enzyme. Quote Link to comment Share on other sites More sharing options...
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