pollutional potpouri - etiologic models for autism & epidemics

[Guest guest]

Herein are links for too many recent studies about pollution physiology

- and these from just one journal (EHP of NIEHS).

The CDC's pre-altered data showed statistically significant associations

between thimerosal injections and a range of neurologic problems - from

ADHD to autism. Many of us are fond of mentioning the current rate(s)

of autism and other ASDs. Some of us seem to prefer placing entire blame

upon thimerosal injections or live-virus injections, but (IMO) that

position ignores the additive and synergistic effects of background

pollutants. Yes, I believe that thimerosal has been a primary factor in

the ongoing epidemics of autism and ASDs. The MMR too has contributed

significantly. However, a very likely scenario is that " background "

toxins increasingly documented in the human body helped set the stage

for thimerosal's and the MMR's adverse effects. Furthermore, the various

severities of autism and ASDs may have - on average and in any given

family - been less severe had the background toxins not been present in

the infant or toddler about to be injected with thimerosal or with live

viruses. A polluted infant or toddler is one whose detoxification

processes are already working overtime, thus whose detox processes are

utilizing nutrients such as glutathione and its precursors, thereby

causing less to be available for detoxifying a bolus dose of ethylmercury.

The abundance of polluted wombs, polluted fetuses, polluted infants, and

polluted toddlers direct attention to politics and economics. News

stories increasingly describe legislative conflicts between (i) people

and groups wanting cleaner locales, and (ii) business spokespersons

mentioning the adverse economic consequences of tighter controls upon

pollution.

Reading the lists and visiting with parents make so tragically clear the

number and costs of supplements and other remedial procedures -

strategies that - though rooted in love and determination - don't always

guarantee the child shall achieve " neurotypical " . This upward slope via

biomedical treatments is hard work and, for most families, well worth

it. The " upward slope " is akin to a mirror of the background toxins

which contribute to the severity of thimerosal's adverse effects. With

fewer intra-body toxins, the child's thimerosal-induced and

live-virus-induced atypicalities are likely to have been less severe,

the likelihood of a family achieving healing all the way to neurotypical

more likely.

Societal policies that allow and encourage toxins that become intra-body

toxins are tragically flawed. Autism models which omit the role of

background toxins are inherently flawed.

[This post may be forwarded hither and yon]

on RR, Seidler FJ, Qiao D, and Slotkin TA. 2005. *

Chlorpyrifos Affects Phenotypic Outcomes in a Model of Mammalian

Neurodevelopment: Critical Stages Targeting Differentiation in PC12 Cells*/

Environ Health Perspect/: doi:10.1289/ehp.8750. [Online 29 December 2005]

http://ehp.niehs.nih.gov/members/2005/8750/8750.pdf

Lamb MR, S, Liu X, Wolff MS, Borrell L, Matte TD, Susser ES, and

Factor-Litvak P. 2005. *

Prenatal Exposure to Polychlorinated Biphenyls (PCBs) and Postnatal

Growth: A Structural Analysis*/

Environ Health Perspect/: doi:10.1289/ehp.8488. [Online 29 December 2005]

http://ehp.niehs.nih.gov/members/2005/8488/8488.pdf

Triche EW, Gent JF, Holford TR, Belanger K, Bracken MB, Beckett WS,

Naeher L, McSharry J-E, Leadere BP. 2005. *

Low-Level Ozone Exposure and Respiratory Symptoms in Infants*/

Environ Health Perspect/: doi:10.1289/ehp.8559. [Online 29 December 2005]

http://ehp.niehs.nih.gov/members/2005/8559/8559.pdf

Tiido T, Rignell-Hydbom A, Jönsson BAG, Giwercman YL, Pedersen HS,

Wojtyniak B, Ludwicki JK, Lesovoy V, Zvyezday V, Spano M, Manicardi G-C,

Bizzaro D, Bonefeld-Jørgensen EC, Toft G, Bonde JP, Rylander L, Hagmar

L, Giwercman A, and INUENDO. 2005. *

Impact of PCB and /p,p/´-DDE Contaminants on Human Sperm Y:X Chromosome

Ratio: Studies in three European Populations and the Inuit Population in

Greenland*/

Environ Health Perspect/: doi:10.1289/ehp.8668. [Online 29 December 2005]

http://ehp.niehs.nih.gov/members/2005/8668/8668.pdf

Klein GP, Hodge EM, Diamond ML, Yip A, Dann T, Stern G, Denison MS, and

Harper PA. 2005. *

Gas-Phase Ambient Air Contaminants Exhibit Significant Dioxin-like and

Estrogen-like Activity /In Vitro/*/

Environ Health Perspect/: doi:10.1289/ehp.8496. [Online 29 December 2005]

http://ehp.niehs.nih.gov/members/2005/8496/8496.pdf

Buffler PA, Kelsh MA, Lau EC, Edinboro CH, Barnard JC, Rutherford GW,

Daaboul JJ, Palmer L, and Lorey FW. 2005. *

Thyroid Function and Perchlorate in Drinking Water: An Evaluation Among

California Newborns, 1998*/

Environ Health Perspect/: doi:10.1289/ehp.8176. [Online 15 December 2005]

http://ehp.niehs.nih.gov/members/2005/8176/8176.pdf

Nakajima S, Saijo Y, Kato S, Sasaki S, Uno A, Kanagami N, Hirakawa H,

Hori T, Tobiishi K, Todaka T, Nakamura Y, Yanagiya S, Sengoku Y, Iida T,

Sata F and Kishi R. 2005. *

Effects of Prenatal Exposure to Polychlorinated Biphenyls and Dioxins on

Mental and Motor Development in Japanese Children at Six Months*/

Environ Health Perspect/: doi:10.1289/ehp.8614. [Online 15 December 2005]

http://ehp.niehs.nih.gov/members/2005/8614/8614.pdf

Fenster L, Eskenazi B, M, Bradman A, Harley K, H,

Hubbard A,and Barr DB. 2005. *

Association of in utero Organochlorine Pesticide Exposure and Fetal

Growth and Length of Gestation in an Agricultural Population*/

Environ Health Perspect/: doi:10.1289/ehp.8423. [Online 2 December 2005]

http://ehp.niehs.nih.gov/members/2005/8423/8423.pdf

Soffritti M, Belpoggi F, Esposti DD, Lambertini L, Tibaldi E, and Rigano

A. 2005. *

First Experimental Demonstration of the Multipotential Carcinogenic

Effects of Aspartame Administered in the Feed to Sprague-Dawley Rats*/

Environ Health Perspect/: doi:10.1289/ehp.8711. [Online 17 November 2005]

http://ehp.niehs.nih.gov/members/2005/8711/8711.pdf

Gordon SM, Brinkman MC, DL, Blount BC, Lyu C, Masters J, and

Singer PC. 2005. *

Changes in Breath Trihalomethane Levels Resulting From Household Water

Use Activities*/

Environ Health Perspect/: doi:10.1289/ehp.8171. [Online 15 November 2005]

http://ehp.niehs.nih.gov/members/2005/8171/8171.pdf

Soffritti M, Belpoggi F, Esposti DD, Lambertini L, Tibaldi E, and Rigano

A. 2005. *

First Experimental Demonstration of the Multipotential Carcinogenic

Effects of Aspartame Administered in the Feed to Sprague-Dawley Rats*/

Environ Health Perspect/: doi:10.1289/ehp.8711. [Online 17 November 2005]

http://ehp.niehs.nih.gov/members/2005/8711/8711.pdf

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