ACTOS diabetes med for autism -Dr JM

June 1, 2005

Dear Dr JM

could you inform us if you developed an opinion on Dr Boris experiment

with ACTOS?I realize its too soon to tell but at least tell us if the

drug is " safe " for a trial.

Thanks for your continued support

Pisinaris

June 1, 2005

I have spoken at length to Alan Goldblatt, who is conducting a study of 80

children, and he is reporting very good results. Actos though designed for

lowering insulin resistance, works as an immune modulator and helps push T2

(auto-immune reactions) to T1 (attacking viruses, fungi, and bacteria). I

gave it to Chelsey, my little guinea pig, and have not seen anything except

an intense hunger so far, and her mom, who has fibromyalgia, was made very

nauseated on it, but she is quite sensitive. One other child seemed to get

better at first but then started having a lot of irritability and whining,

and as soon as his mother took him off it, he got happy again. So my

limited use so far is not too glowing, but I can certainly come to no

conclusions yet. I don't think I want to prescribe it anymore until Alan's

studies are completed. We will be asking Alan for an update at the October

DAN!, and by then or hopefully sooner I think the criteria will be in place

to know which kids it should be used for. I believe glucose levels have to

be watched carefully if the kids are small or underweight; I'm not sure

about the bigger or heavier kids. I'll report when I know more. Dr. JM

ACTOS diabetes med for autism -Dr JM

> Dear Dr JM

> could you inform us if you developed an opinion on Dr Boris experiment

> with ACTOS?I realize its too soon to tell but at least tell us if the

> drug is " safe " for a trial.

>

> Thanks for your continued support

> Pisinaris

>

> Many frequently asked questions and answers can be found at

>

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