clinical trials becoming safer

[Guest guest]

The risk of a cancer patient dying from an experimental treatment while participating in a phase 1 clinical trial decreased about tenfold between 1991 and 2002, according to a study led by researchers from Harvard Medical School. During the same period, response rates to treatment (as measured by tumor shrinkage) also decreased, though by a much smaller amount. Researchers suggest that both these trends may be explained in part by the emergence of new targeted cancer drugs that are less toxic and that often work by stopping tumor growth rather than by shrinking tumors

snip

The finding that phase 1 trials are safer should not be interpreted to mean that patients who take part in these trials are more likely than in the past to be cured or to live longer - the study did not address those issues.

Nonetheless, says Doroshow, M.D., director of the Division of Cancer Treatment and Diagnosis at the National Cancer Institute, “this study demonstrates that the risk of participating in early clinical trials has decreased substantially. The fact that traditional response criteria [tumor shrinkage] were used means that the potential clinical benefit of the therapies studied - in terms of quality of life benefit or prolonged disease stabilization - was probably underreported.”

http://www.cancer.gov/clinicaltrials/results/phase1-trials-safer1104

Kathy Meadehttp://www.vapcacoalition.org/

Arlington Educational Consulting

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fax

'To see what is right and not to do it is cowardice." -- Confucius

[Guest guest]

Means that I did not copy the entire article. There are additional part deleted where the word snip is. I put the link there if you want to read the whole article.

Kathy

-----Original Message-----From: darrylmit@... Sent: Monday, November 22, 2004 2:15 PMTo: ProstateCancerSupport Subject: Re: clinical trials becoming safer

What does "snip" mean? Darryl from http://www.malecare.com

[Guest guest]

Good question Darryl, I've wondered the same thing, and also wondered if the word "snip" is inserted automatically, or typewritten, when a person cuts and pastes?

RJ

near Houston TX

Re: clinical trials becoming safer

What does "snip" mean? Darryl from http://www.malecare.com

[Guest guest]

Using <snip>

is just an Internet convention to show when something has been cut and pasted. It

is inserted manually at the beginning and end of the piece that is cut and

pasted because it is easier to see than “ and because it clearly delineates

what the person has written and what they are quoting.

All the best

Terry Herbert

in sunny Kalk

Bay, South Africa

Diagnosed ‘96:

Age 54: Stage T2b: PSA 7.2: Gleason 3+3=6: No treatment. June '04: TURP. Sep

'04 PSA 7.45 fPSA 42%

My site is at

www.prostatecancerwatchfulwaiting.co.za

It is a tragedy of the world that no one knows what he

doesn’t know, and the less a man knows, the more sure he is that he knows

everything. Joyce Carey

-----Original

Message-----

From: RJ

Sent: 23 November 2004 02:03

To:

ProstateCancerSupport

Subject: Re:

clinical trials becoming safer

Good

question Darryl, I've wondered the same thing, and also wondered if the word

" snip " is inserted automatically, or typewritten, when a person

cuts and pastes?

RJ

near

Houston TX

-----

Original Message -----

From: darrylmit@...

To: ProstateCancerSupport

Sent: Monday, November 22,

2004 1:14 PM

Subject: Re:

clinical trials becoming safer

What does " snip " mean? Darryl from http://www.malecare.com