Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 Hi It will be interesting to see how your test results turn out. Most people I have talked to that have KPU have love zink and high copper. I would not do KPU without the KPU test and I don't feel its a good thing to do this without Md guidance. There r warnings everywhere about this. People can get into serious trouble with the protocol. I am aware people r doing it on there own and that's their choice.The sad thing is that many cannot find Mds to help them and I understand that. Taking zink and the rest of the protocol the copper levels can go low. Which mine did and we added very small amounts of copper.I was taking it with the KPU and have found it needs to be taken away,about 2-3 hrs away. In a lot of the Dr K info he talks about adding in copper down the line. Healing Blessings JoyceSubject: Chelating, low Copper, comprimised immune functionTo: Lyme_and_Rife Date: Sunday, April 25, 2010, 8:05 PM Copper and Immune Function It has been well documented that adequate copper status is essential for normal functioning of the immune system in laboratory and domestic animals.47 For instance, not only has it been shown that the functioning of macrophages were decreased in severely copper deficient rats, but even marginally copper-deficient rats had impaired immune functioning.48 Interestingly, immune function was significantly impaired at dietary copper levels that didn't seem to decrease tissue copper or the activity of red blood cell Cu,Zn-superoxide dismutase (SOD).49 However, neutrophil SOD-activity and neutrophil function was significantly diminished, suggesting that immune function may be more sensitive to diets low in copper than standard measures of copper status. It was also found that immune impairment could be detected as soon as one week after the initiation of a diet low or marginal in copper, and the addition of adequate copper reversed the immune suppression within one week of supplementation. The authors concluded that, "...the adverse effects of inadequate copper intake on neutrophil activity occur rapidly and are readily reversed by dietary copper repletion." Additionally, it has been demonstrated that copper deficiency reversibly impairs DNA synthesis in activated T-cells by limiting interleukin 2 activity up to 50%, and this was reversible with copper supplementation.50 Because of this sensitivity to copper status at levels of intake that have little effect on other indicators of copper status, immune system cells have been suggested to be a readily accessible and copper-status sensitive population of cells for the assessment of copper status.51 http://www.oralchel ation.com/ technical/ copper1.htmSo, I've spent the day researching because I am a little concerned over my son's very low copper level and my marginally low level. (Still awaiting KPU results). Of course, for both of us our zinc was at the lower end of the range as well. This is interesting because I've supplemented with 50 mg of zinc for a few years, on and off, and am surprised that I would be low. It made me really think about all of the chelating we do and how we can take the good with the bad. (My son hasn't done any chelating, so his levels are of even greater concern). My thought is to everyone, to be careful and have your serum levels check of minerals every so often. I was tempted to start the KPU protocol and not spend the time or money on any testing. Had we done this, mine and my son's copper levels would begin to plummet and I would have had no idea that it was happening. Although copper has received some bad press the last few years, it does have important functions and being deficient is just as bad.Take good care, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 Yep, on the doctor thing. I think I'll call EHS today. I also think since my son was below range in copper, that I will pick up a copper supplement for him today and get him started. It is not good to be deficient in this mineral. Hi It will be interesting to see how your test results turn out. Most people I have talked to that have KPU have love zink and high copper. I would not do KPU without the KPU test and I don't feel its a good thing to do this without Md guidance. There r warnings everywhere about this. People can get into serious trouble with the protocol. I am aware people r doing it on there own and that's their choice.The sad thing is that many cannot find Mds to help them and I understand that. Taking zink and the rest of the protocol the copper levels can go low. Which mine did and we added very small amounts of copper.I was taking it with the KPU and have found it needs to be taken away,about 2-3 hrs away. In a lot of the Dr K info he talks about adding in copper down the line. Healing Blessings Joyce Subject: Chelating, low Copper, comprimised immune functionTo: Lyme_and_Rife Date: Sunday, April 25, 2010, 8:05 PM Copper and Immune Function It has been well documented that adequate copper status is essential for normal functioning of the immune system in laboratory and domestic animals.47 For instance, not only has it been shown that the functioning of macrophages were decreased in severely copper deficient rats, but even marginally copper-deficient rats had impaired immune functioning.48 Interestingly, immune function was significantly impaired at dietary copper levels that didn't seem to decrease tissue copper or the activity of red blood cell Cu,Zn-superoxide dismutase (SOD).49 However, neutrophil SOD-activity and neutrophil function was significantly diminished, suggesting that immune function may be more sensitive to diets low in copper than standard measures of copper status. It was also found that immune impairment could be detected as soon as one week after the initiation of a diet low or marginal in copper, and the addition of adequate copper reversed the immune suppression within one week of supplementation. The authors concluded that, " ...the adverse effects of inadequate copper intake on neutrophil activity occur rapidly and are readily reversed by dietary copper repletion. " Additionally, it has been demonstrated that copper deficiency reversibly impairs DNA synthesis in activated T-cells by limiting interleukin 2 activity up to 50%, and this was reversible with copper supplementation.50 Because of this sensitivity to copper status at levels of intake that have little effect on other indicators of copper status, immune system cells have been suggested to be a readily accessible and copper-status sensitive population of cells for the assessment of copper status.51 http://www.oralchel ation.com/ technical/ copper1.htm So, I've spent the day researching because I am a little concerned over my son's very low copper level and my marginally low level. (Still awaiting KPU results). Of course, for both of us our zinc was at the lower end of the range as well. This is interesting because I've supplemented with 50 mg of zinc for a few years, on and off, and am surprised that I would be low. It made me really think about all of the chelating we do and how we can take the good with the bad. (My son hasn't done any chelating, so his levels are of even greater concern). My thought is to everyone, to be careful and have your serum levels check of minerals every so often. I was tempted to start the KPU protocol and not spend the time or money on any testing. Had we done this, mine and my son's copper levels would begin to plummet and I would have had no idea that it was happening. Although copper has received some bad press the last few years, it does have important functions and being deficient is just as bad.Take good care, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 Hi , There is a copper/zinc ratio, it is 15:1... Many supps are sold in this strength, or you can take zinc 15 mg for each copper 1 mg taken... This is also very important as a low zinc to copper ration weakens arteries and blood vessels and thus aneurysms can form. Take care, Jim > > > > Copper and Immune Function > It has been well documented that adequate copper status is essential > for normal functioning of the immune system in laboratory and domestic > animals.47 <http://www.oralchelation.com/technical/copper1.htm#47> For > instance, not only has it been shown that the functioning of macrophages > were decreased in severely copper deficient rats, but even marginally > copper-deficient rats had impaired immune functioning.48 > <http://www.oralchelation.com/technical/copper1.htm#48> Interestingly, > immune function was significantly impaired at dietary copper levels > that didn't seem to decrease tissue copper or the activity of red blood > cell Cu,Zn-superoxide dismutase (SOD).49 > <http://www.oralchelation.com/technical/copper1.htm#49> However, > neutrophil SOD-activity and neutrophil function was significantly > diminished, suggesting that immune function may be more sensitive to > diets low in copper than standard measures of copper status. It was > also found that immune impairment could be detected as soon as one week > after the initiation of a diet low or marginal in copper, and the > addition of adequate copper reversed the immune suppression within one > week of supplementation. The authors concluded that, " ...the adverse > effects of inadequate copper intake on neutrophil activity occur > rapidly and are readily reversed by dietary copper repletion. " > Additionally, it has been demonstrated that copper deficiency > reversibly impairs DNA synthesis in activated T-cells by limiting > interleukin 2 activity up to 50%, and this was reversible with copper > supplementation.50 > <http://www.oralchelation.com/technical/copper1.htm#50> Because of > this sensitivity to copper status at levels of intake that have little > effect on other indicators of copper status, immune system cells have > been suggested to be a readily accessible and copper-status sensitive > population of cells for the assessment of copper status.51 > <http://www.oralchelation.com/technical/copper1.htm#51> > http://www.oralchelation.com/technical/copper1.htm > > > > > So, I've spent the day researching because I am a little concerned over > my son's very low copper level and my marginally low level. (Still > awaiting KPU results). > > Of course, for both of us our zinc was at the lower end of the range as > well. This is interesting because I've supplemented with 50 mg of zinc > for a few years, on and off, and am surprised that I would be low. It > made me really think about all of the chelating we do and how we can > take the good with the bad. (My son hasn't done any chelating, so his > levels are of even greater concern). > > My thought is to everyone, to be careful and have your serum levels > check of minerals every so often. I was tempted to start the KPU > protocol and not spend the time or money on any testing. Had we done > this, mine and my son's copper levels would begin to plummet and I would > have had no idea that it was happening. > > Although copper has received some bad press the last few years, it does > have important functions and being deficient is just as bad. > > > > > Take good care, > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 Hey Jim, If a person has KPU its a whole different ball game sorry to say. Take care JSubject: Re: Chelating, low Copper, comprimised immune functionTo: Lyme_and_Rife Date: Monday, April 26, 2010, 10:11 AM Hi , There is a copper/zinc ratio, it is 15:1... Many supps are sold in this strength, or you can take zinc 15 mg for each copper 1 mg taken... This is also very important as a low zinc to copper ration weakens arteries and blood vessels and thus aneurysms can form. Take care, Jim > > > > Copper and Immune Function > It has been well documented that adequate copper status is essential > for normal functioning of the immune system in laboratory and domestic > animals.47 <http://www.oralchel ation.com/ technical/ copper1.htm# 47> For > instance, not only has it been shown that the functioning of macrophages > were decreased in severely copper deficient rats, but even marginally > copper-deficient rats had impaired immune functioning. 48 > <http://www.oralchel ation.com/ technical/ copper1.htm# 48> Interestingly, > immune function was significantly impaired at dietary copper levels > that didn't seem to decrease tissue copper or the activity of red blood > cell Cu,Zn-superoxide dismutase (SOD).49 > <http://www.oralchel ation.com/ technical/ copper1.htm# 49> However, > neutrophil SOD-activity and neutrophil function was significantly > diminished, suggesting that immune function may be more sensitive to > diets low in copper than standard measures of copper status. It was > also found that immune impairment could be detected as soon as one week > after the initiation of a diet low or marginal in copper, and the > addition of adequate copper reversed the immune suppression within one > week of supplementation. The authors concluded that, "...the adverse > effects of inadequate copper intake on neutrophil activity occur > rapidly and are readily reversed by dietary copper repletion." > Additionally, it has been demonstrated that copper deficiency > reversibly impairs DNA synthesis in activated T-cells by limiting > interleukin 2 activity up to 50%, and this was reversible with copper > supplementation. 50 > <http://www.oralchel ation.com/ technical/ copper1.htm# 50> Because of > this sensitivity to copper status at levels of intake that have little > effect on other indicators of copper status, immune system cells have > been suggested to be a readily accessible and copper-status sensitive > population of cells for the assessment of copper status.51 > <http://www.oralchel ation.com/ technical/ copper1.htm# 51> > http://www.oralchel ation.com/ technical/ copper1.htm > > > > > So, I've spent the day researching because I am a little concerned over > my son's very low copper level and my marginally low level. (Still > awaiting KPU results). > > Of course, for both of us our zinc was at the lower end of the range as > well. This is interesting because I've supplemented with 50 mg of zinc > for a few years, on and off, and am surprised that I would be low. It > made me really think about all of the chelating we do and how we can > take the good with the bad. (My son hasn't done any chelating, so his > levels are of even greater concern). > > My thought is to everyone, to be careful and have your serum levels > check of minerals every so often. I was tempted to start the KPU > protocol and not spend the time or money on any testing. Had we done > this, mine and my son's copper levels would begin to plummet and I would > have had no idea that it was happening. > > Although copper has received some bad press the last few years, it does > have important functions and being deficient is just as bad. > > > > > Take good care, > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 Hi Jim,Thanks. That may work for me, but I think we will need to give my son more copper - and plenty more blood checks. Interestingly enough the article I quoted part of had a paragraph on strength of blood vessel walls as well: In copper deficiency the level of lysyl oxidase isn't altered, but the activity of the enzyme can be reduced by more than fifty percent.7 Not surprisingly, some of the hallmarks of copper deficiency are connective tissue disorders, osteoporosis, and blood vessel damage.It's such a tricky balance.Health and Blessings, Hi , There is a copper/zinc ratio, it is 15:1... Many supps are sold in this strength, or you can take zinc 15 mg for each copper 1 mg taken... This is also very important as a low zinc to copper ration weakens arteries and blood vessels and thus aneurysms can form. Take care, Jim > > > > Copper and Immune Function > It has been well documented that adequate copper status is essential > for normal functioning of the immune system in laboratory and domestic > animals.47 <http://www.oralchelation.com/technical/copper1.htm#47> For > instance, not only has it been shown that the functioning of macrophages > were decreased in severely copper deficient rats, but even marginally > copper-deficient rats had impaired immune functioning.48 > <http://www.oralchelation.com/technical/copper1.htm#48> Interestingly, > immune function was significantly impaired at dietary copper levels > that didn't seem to decrease tissue copper or the activity of red blood > cell Cu,Zn-superoxide dismutase (SOD).49 > <http://www.oralchelation.com/technical/copper1.htm#49> However, > neutrophil SOD-activity and neutrophil function was significantly > diminished, suggesting that immune function may be more sensitive to > diets low in copper than standard measures of copper status. It was > also found that immune impairment could be detected as soon as one week > after the initiation of a diet low or marginal in copper, and the > addition of adequate copper reversed the immune suppression within one > week of supplementation. The authors concluded that, " ...the adverse > effects of inadequate copper intake on neutrophil activity occur > rapidly and are readily reversed by dietary copper repletion. " > Additionally, it has been demonstrated that copper deficiency > reversibly impairs DNA synthesis in activated T-cells by limiting > interleukin 2 activity up to 50%, and this was reversible with copper > supplementation.50 > <http://www.oralchelation.com/technical/copper1.htm#50> Because of > this sensitivity to copper status at levels of intake that have little > effect on other indicators of copper status, immune system cells have > been suggested to be a readily accessible and copper-status sensitive > population of cells for the assessment of copper status.51 > <http://www.oralchelation.com/technical/copper1.htm#51> > http://www.oralchelation.com/technical/copper1.htm > > > > > So, I've spent the day researching because I am a little concerned over > my son's very low copper level and my marginally low level. (Still > awaiting KPU results). > > Of course, for both of us our zinc was at the lower end of the range as > well. This is interesting because I've supplemented with 50 mg of zinc > for a few years, on and off, and am surprised that I would be low. It > made me really think about all of the chelating we do and how we can > take the good with the bad. (My son hasn't done any chelating, so his > levels are of even greater concern). > > My thought is to everyone, to be careful and have your serum levels > check of minerals every so often. I was tempted to start the KPU > protocol and not spend the time or money on any testing. Had we done > this, mine and my son's copper levels would begin to plummet and I would > have had no idea that it was happening. > > Although copper has received some bad press the last few years, it does > have important functions and being deficient is just as bad. > > > > > Take good care, > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 Hi Jim,I just want to be clear: the 15:1 ratio is for copper: zinc, like you wrote, or zinc:copper? Your second sentence makes me think it's the zinc in higer number, but want to be sure.=)Be well,Léna Hi , There is a copper/zinc ratio, it is 15:1... Many supps are sold in this strength, or you can take zinc 15 mg for each copper 1 mg taken... This is also very important as a low zinc to copper ration weakens arteries and blood vessels and thus aneurysms can form. Take care, Jim > > > > Copper and Immune Function > It has been well documented that adequate copper status is essential > for normal functioning of the immune system in laboratory and domestic > animals.47 <http://www.oralchelation.com/technical/copper1.htm#47> For > instance, not only has it been shown that the functioning of macrophages > were decreased in severely copper deficient rats, but even marginally > copper-deficient rats had impaired immune functioning.48 > <http://www.oralchelation.com/technical/copper1.htm#48> Interestingly, > immune function was significantly impaired at dietary copper levels > that didn't seem to decrease tissue copper or the activity of red blood > cell Cu,Zn-superoxide dismutase (SOD).49 > <http://www.oralchelation.com/technical/copper1.htm#49> However, > neutrophil SOD-activity and neutrophil function was significantly > diminished, suggesting that immune function may be more sensitive to > diets low in copper than standard measures of copper status. It was > also found that immune impairment could be detected as soon as one week > after the initiation of a diet low or marginal in copper, and the > addition of adequate copper reversed the immune suppression within one > week of supplementation. The authors concluded that, "...the adverse > effects of inadequate copper intake on neutrophil activity occur > rapidly and are readily reversed by dietary copper repletion." > Additionally, it has been demonstrated that copper deficiency > reversibly impairs DNA synthesis in activated T-cells by limiting > interleukin 2 activity up to 50%, and this was reversible with copper > supplementation.50 > <http://www.oralchelation.com/technical/copper1.htm#50> Because of > this sensitivity to copper status at levels of intake that have little > effect on other indicators of copper status, immune system cells have > been suggested to be a readily accessible and copper-status sensitive > population of cells for the assessment of copper status.51 > <http://www.oralchelation.com/technical/copper1.htm#51> > http://www.oralchelation.com/technical/copper1.htm > > > > > So, I've spent the day researching because I am a little concerned over > my son's very low copper level and my marginally low level. (Still > awaiting KPU results). > > Of course, for both of us our zinc was at the lower end of the range as > well. This is interesting because I've supplemented with 50 mg of zinc > for a few years, on and off, and am surprised that I would be low. It > made me really think about all of the chelating we do and how we can > take the good with the bad. (My son hasn't done any chelating, so his > levels are of even greater concern). > > My thought is to everyone, to be careful and have your serum levels > check of minerals every so often. I was tempted to start the KPU > protocol and not spend the time or money on any testing. Had we done > this, mine and my son's copper levels would begin to plummet and I would > have had no idea that it was happening. > > Although copper has received some bad press the last few years, it does > have important functions and being deficient is just as bad. > > > > > Take good care, > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 thanks for this linda. i'm glad you caught it sooner rather than later. do you get serum levels through a regular lab? covered by insurance? xosusie Copper and Immune Function It has been well documented that adequate copper status is essential for normal functioning of the immune system in laboratory and domestic animals.47 For instance, not only has it been shown that the functioning of macrophages were decreased in severely copper deficient rats, but even marginally copper-deficient rats had impaired immune functioning.48 Interestingly, immune function was significantly impaired at dietary copper levels that didn't seem to decrease tissue copper or the activity of red blood cell Cu,Zn-superoxide dismutase (SOD).49 However, neutrophil SOD-activity and neutrophil function was significantly diminished, suggesting that immune function may be more sensitive to diets low in copper than standard measures of copper status. It was also found that immune impairment could be detected as soon as one week after the initiation of a diet low or marginal in copper, and the addition of adequate copper reversed the immune suppression within one week of supplementation. The authors concluded that, "...the adverse effects of inadequate copper intake on neutrophil activity occur rapidly and are readily reversed by dietary copper repletion." Additionally, it has been demonstrated that copper deficiency reversibly impairs DNA synthesis in activated T-cells by limiting interleukin 2 activity up to 50%, and this was reversible with copper supplementation.50 Because of this sensitivity to copper status at levels of intake that have little effect on other indicators of copper status, immune system cells have been suggested to be a readily accessible and copper-status sensitive population of cells for the assessment of copper status.51 http://www.oralchelation.com/technical/copper1.htm Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 Good catch Lena! This should have read the zinc/copper ration is 15:1, not the copper/zinc ratio... And I gotta tell you, I reread that to be sure I had it right! So , I hope you caught this correction! Take care, Jim > > > > > > > > > > > > Copper and Immune Function > > > It has been well documented that adequate copper status is essential > > > for normal functioning of the immune system in laboratory and > > domestic > > > animals.47 <http://www.oralchelation.com/technical/ > > copper1.htm#47> For > > > instance, not only has it been shown that the functioning of > > macrophages > > > were decreased in severely copper deficient rats, but even > > marginally > > > copper-deficient rats had impaired immune functioning.48 > > > <http://www.oralchelation.com/technical/copper1.htm#48> > > Interestingly, > > > immune function was significantly impaired at dietary copper levels > > > that didn't seem to decrease tissue copper or the activity of red > > blood > > > cell Cu,Zn-superoxide dismutase (SOD).49 > > > <http://www.oralchelation.com/technical/copper1.htm#49> However, > > > neutrophil SOD-activity and neutrophil function was significantly > > > diminished, suggesting that immune function may be more sensitive to > > > diets low in copper than standard measures of copper status. It was > > > also found that immune impairment could be detected as soon as > > one week > > > after the initiation of a diet low or marginal in copper, and the > > > addition of adequate copper reversed the immune suppression > > within one > > > week of supplementation. The authors concluded that, " ...the adverse > > > effects of inadequate copper intake on neutrophil activity occur > > > rapidly and are readily reversed by dietary copper repletion. " > > > Additionally, it has been demonstrated that copper deficiency > > > reversibly impairs DNA synthesis in activated T-cells by limiting > > > interleukin 2 activity up to 50%, and this was reversible with > > copper > > > supplementation.50 > > > <http://www.oralchelation.com/technical/copper1.htm#50> Because of > > > this sensitivity to copper status at levels of intake that have > > little > > > effect on other indicators of copper status, immune system cells > > have > > > been suggested to be a readily accessible and copper-status > > sensitive > > > population of cells for the assessment of copper status.51 > > > <http://www.oralchelation.com/technical/copper1.htm#51> > > > http://www.oralchelation.com/technical/copper1.htm > > > > > > > > > > > > > > > So, I've spent the day researching because I am a little > > concerned over > > > my son's very low copper level and my marginally low level. (Still > > > awaiting KPU results). > > > > > > Of course, for both of us our zinc was at the lower end of the > > range as > > > well. This is interesting because I've supplemented with 50 mg of > > zinc > > > for a few years, on and off, and am surprised that I would be > > low. It > > > made me really think about all of the chelating we do and how we can > > > take the good with the bad. (My son hasn't done any chelating, so > > his > > > levels are of even greater concern). > > > > > > My thought is to everyone, to be careful and have your serum levels > > > check of minerals every so often. I was tempted to start the KPU > > > protocol and not spend the time or money on any testing. Had we done > > > this, mine and my son's copper levels would begin to plummet and > > I would > > > have had no idea that it was happening. > > > > > > Although copper has received some bad press the last few years, > > it does > > > have important functions and being deficient is just as bad. > > > > > > > > > > > > > > > Take good care, > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 LOL Glad other people do things like this. Makes me feel more normal. What ever normal is. Funny thing is,I am seeing more and more normies do these things. JoyceSubject: Re: Chelating, low Copper, comprimised immune functionTo: Lyme_and_Rife Date: Monday, April 26, 2010, 1:49 PM Good catch Lena! This should have read the zinc/copper ration is 15:1, not the copper/zinc ratio... And I gotta tell you, I reread that to be sure I had it right! So , I hope you caught this correction! Take care, Jim > > > > > > > > > > > > Copper and Immune Function > > > It has been well documented that adequate copper status is essential > > > for normal functioning of the immune system in laboratory and > > domestic > > > animals.47 <http://www.oralchel ation.com/ technical/ > > copper1.htm# 47> For > > > instance, not only has it been shown that the functioning of > > macrophages > > > were decreased in severely copper deficient rats, but even > > marginally > > > copper-deficient rats had impaired immune functioning. 48 > > > <http://www.oralchel ation.com/ technical/ copper1.htm# 48> > > Interestingly, > > > immune function was significantly impaired at dietary copper levels > > > that didn't seem to decrease tissue copper or the activity of red > > blood > > > cell Cu,Zn-superoxide dismutase (SOD).49 > > > <http://www.oralchel ation.com/ technical/ copper1.htm# 49> However, > > > neutrophil SOD-activity and neutrophil function was significantly > > > diminished, suggesting that immune function may be more sensitive to > > > diets low in copper than standard measures of copper status. It was > > > also found that immune impairment could be detected as soon as > > one week > > > after the initiation of a diet low or marginal in copper, and the > > > addition of adequate copper reversed the immune suppression > > within one > > > week of supplementation. The authors concluded that, "...the adverse > > > effects of inadequate copper intake on neutrophil activity occur > > > rapidly and are readily reversed by dietary copper repletion." > > > Additionally, it has been demonstrated that copper deficiency > > > reversibly impairs DNA synthesis in activated T-cells by limiting > > > interleukin 2 activity up to 50%, and this was reversible with > > copper > > > supplementation. 50 > > > <http://www.oralchel ation.com/ technical/ copper1.htm# 50> Because of > > > this sensitivity to copper status at levels of intake that have > > little > > > effect on other indicators of copper status, immune system cells > > have > > > been suggested to be a readily accessible and copper-status > > sensitive > > > population of cells for the assessment of copper status.51 > > > <http://www.oralchel ation.com/ technical/ copper1.htm# 51> > > > http://www.oralchel ation.com/ technical/ copper1.htm > > > > > > > > > > > > > > > So, I've spent the day researching because I am a little > > concerned over > > > my son's very low copper level and my marginally low level. (Still > > > awaiting KPU results). > > > > > > Of course, for both of us our zinc was at the lower end of the > > range as > > > well. This is interesting because I've supplemented with 50 mg of > > zinc > > > for a few years, on and off, and am surprised that I would be > > low. It > > > made me really think about all of the chelating we do and how we can > > > take the good with the bad. (My son hasn't done any chelating, so > > his > > > levels are of even greater concern). > > > > > > My thought is to everyone, to be careful and have your serum levels > > > check of minerals every so often. I was tempted to start the KPU > > > protocol and not spend the time or money on any testing. Had we done > > > this, mine and my son's copper levels would begin to plummet and > > I would > > > have had no idea that it was happening. > > > > > > Although copper has received some bad press the last few years, > > it does > > > have important functions and being deficient is just as bad. > > > > > > > > > > > > > > > Take good care, > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 Hi Jim,The only reason i caught it was because I'm in mind-fog mode these days approaching full moon, so I find myself needing to re-read everything at least twice to make sense of it at all.I hope you're feeling better this afternoon.Be well,Léna Good catch Lena! This should have read the zinc/copper ration is 15:1, not the copper/zinc ratio... And I gotta tell you, I reread that to be sure I had it right! So , I hope you caught this correction! Take care, Jim > > > > > > > > > > > > Copper and Immune Function > > > It has been well documented that adequate copper status is essential > > > for normal functioning of the immune system in laboratory and > > domestic > > > animals.47 <http://www.oralchelation.com/technical/ > > copper1.htm#47> For > > > instance, not only has it been shown that the functioning of > > macrophages > > > were decreased in severely copper deficient rats, but even > > marginally > > > copper-deficient rats had impaired immune functioning.48 > > > <http://www.oralchelation.com/technical/copper1.htm#48> > > Interestingly, > > > immune function was significantly impaired at dietary copper levels > > > that didn't seem to decrease tissue copper or the activity of red > > blood > > > cell Cu,Zn-superoxide dismutase (SOD).49 > > > <http://www.oralchelation.com/technical/copper1.htm#49> However, > > > neutrophil SOD-activity and neutrophil function was significantly > > > diminished, suggesting that immune function may be more sensitive to > > > diets low in copper than standard measures of copper status. It was > > > also found that immune impairment could be detected as soon as > > one week > > > after the initiation of a diet low or marginal in copper, and the > > > addition of adequate copper reversed the immune suppression > > within one > > > week of supplementation. The authors concluded that, "...the adverse > > > effects of inadequate copper intake on neutrophil activity occur > > > rapidly and are readily reversed by dietary copper repletion." > > > Additionally, it has been demonstrated that copper deficiency > > > reversibly impairs DNA synthesis in activated T-cells by limiting > > > interleukin 2 activity up to 50%, and this was reversible with > > copper > > > supplementation.50 > > > <http://www.oralchelation.com/technical/copper1.htm#50> Because of > > > this sensitivity to copper status at levels of intake that have > > little > > > effect on other indicators of copper status, immune system cells > > have > > > been suggested to be a readily accessible and copper-status > > sensitive > > > population of cells for the assessment of copper status.51 > > > <http://www.oralchelation.com/technical/copper1.htm#51> > > > http://www.oralchelation.com/technical/copper1.htm > > > > > > > > > > > > > > > So, I've spent the day researching because I am a little > > concerned over > > > my son's very low copper level and my marginally low level. (Still > > > awaiting KPU results). > > > > > > Of course, for both of us our zinc was at the lower end of the > > range as > > > well. This is interesting because I've supplemented with 50 mg of > > zinc > > > for a few years, on and off, and am surprised that I would be > > low. It > > > made me really think about all of the chelating we do and how we can > > > take the good with the bad. (My son hasn't done any chelating, so > > his > > > levels are of even greater concern). > > > > > > My thought is to everyone, to be careful and have your serum levels > > > check of minerals every so often. I was tempted to start the KPU > > > protocol and not spend the time or money on any testing. Had we done > > > this, mine and my son's copper levels would begin to plummet and > > I would > > > have had no idea that it was happening. > > > > > > Although copper has received some bad press the last few years, > > it does > > > have important functions and being deficient is just as bad. > > > > > > > > > > > > > > > Take good care, > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 26, 2010 Report Share Posted April 26, 2010 Well then Lena! What's my excuse, I also re-read it and still didn't catch it... :-) Oh well, I made Joyce feel better... :-) Jim > > > > > > > > > > > > > > > > > > > > Copper and Immune Function > > > > > It has been well documented that adequate copper status is > > essential > > > > > for normal functioning of the immune system in laboratory and > > > > domestic > > > > > animals.47 <http://www.oralchelation.com/technical/ > > > > copper1.htm#47> For > > > > > instance, not only has it been shown that the functioning of > > > > macrophages > > > > > were decreased in severely copper deficient rats, but even > > > > marginally > > > > > copper-deficient rats had impaired immune functioning.48 > > > > > <http://www.oralchelation.com/technical/copper1.htm#48> > > > > Interestingly, > > > > > immune function was significantly impaired at dietary copper > > levels > > > > > that didn't seem to decrease tissue copper or the activity of > > red > > > > blood > > > > > cell Cu,Zn-superoxide dismutase (SOD).49 > > > > > <http://www.oralchelation.com/technical/copper1.htm#49> However, > > > > > neutrophil SOD-activity and neutrophil function was > > significantly > > > > > diminished, suggesting that immune function may be more > > sensitive to > > > > > diets low in copper than standard measures of copper status. > > It was > > > > > also found that immune impairment could be detected as soon as > > > > one week > > > > > after the initiation of a diet low or marginal in copper, and > > the > > > > > addition of adequate copper reversed the immune suppression > > > > within one > > > > > week of supplementation. The authors concluded that, " ...the > > adverse > > > > > effects of inadequate copper intake on neutrophil activity occur > > > > > rapidly and are readily reversed by dietary copper repletion. " > > > > > Additionally, it has been demonstrated that copper deficiency > > > > > reversibly impairs DNA synthesis in activated T-cells by > > limiting > > > > > interleukin 2 activity up to 50%, and this was reversible with > > > > copper > > > > > supplementation.50 > > > > > <http://www.oralchelation.com/technical/copper1.htm#50> > > Because of > > > > > this sensitivity to copper status at levels of intake that have > > > > little > > > > > effect on other indicators of copper status, immune system cells > > > > have > > > > > been suggested to be a readily accessible and copper-status > > > > sensitive > > > > > population of cells for the assessment of copper status.51 > > > > > <http://www.oralchelation.com/technical/copper1.htm#51> > > > > > http://www.oralchelation.com/technical/copper1.htm > > > > > > > > > > > > > > > > > > > > > > > > > So, I've spent the day researching because I am a little > > > > concerned over > > > > > my son's very low copper level and my marginally low level. > > (Still > > > > > awaiting KPU results). > > > > > > > > > > Of course, for both of us our zinc was at the lower end of the > > > > range as > > > > > well. This is interesting because I've supplemented with 50 > > mg of > > > > zinc > > > > > for a few years, on and off, and am surprised that I would be > > > > low. It > > > > > made me really think about all of the chelating we do and how > > we can > > > > > take the good with the bad. (My son hasn't done any > > chelating, so > > > > his > > > > > levels are of even greater concern). > > > > > > > > > > My thought is to everyone, to be careful and have your serum > > levels > > > > > check of minerals every so often. I was tempted to start the KPU > > > > > protocol and not spend the time or money on any testing. Had > > we done > > > > > this, mine and my son's copper levels would begin to plummet and > > > > I would > > > > > have had no idea that it was happening. > > > > > > > > > > Although copper has received some bad press the last few years, > > > > it does > > > > > have important functions and being deficient is just as bad. > > > > > > > > > > > > > > > > > > > > > > > > > Take good care, > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 27, 2010 Report Share Posted April 27, 2010 Hi Jim,Here's a great story to make you feel better.The Folger Library printed a special limited edition (500) of Shakespeare's Hamlet: exquisite typography, Moroccan leather binding, 24kt gold leaf-stamped titles, the whole works. Of course it was carefully scrutinized and proof-read, at every stage, but still, it wasn't until the books came from the bindery that the mistake was found, by someone who whimsically opened to one of the most iconic lines in the whole play, and yep, on that benighted page, Hamlet said,"To be, or to be: that is the question." =o)Be well,Léna Well then Lena! What's my excuse, I also re-read it and still didn't catch it... :-) Oh well, I made Joyce feel better... :-) Jim Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 27, 2010 Report Share Posted April 27, 2010 Hey Lena, Not Jim but that was very funny.Thanks for sharing. Maybe he had lyme brain. Ya think? Joyce Well then Lena! What's my excuse, I also re-read it and still didn't catch it... :-) Oh well, I made Joyce feel better... :-) Jim Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 27, 2010 Report Share Posted April 27, 2010 Probably a tick rode in on the rosemary Ophelia picked! (They do have Lyme in Denmark, yes?) °, L Hey Lena, Not Jim but that was very funny.Thanks for sharing. Maybe he had lyme brain. Ya think? Joyce Well then Lena! What's my excuse, I also re-read it and still didn't catch it... :-) Oh well, I made Joyce feel better... :-) Jim Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 27, 2010 Report Share Posted April 27, 2010 Loving the lightness and laughter here. Thanks Lena Well then Lena! What's my excuse, I also re-read it and still didn't catch it... :-) Oh well, I made Joyce feel better... :-) Jim Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 27, 2010 Report Share Posted April 27, 2010 Well Lena, At least you managed to put a big smile on my face... :-) Jim > > > > > Well then Lena! > > > > What's my excuse, I also re-read it and still didn't catch it... :-) > > > > Oh well, I made Joyce feel better... :-) > > > > Jim > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 27, 2010 Report Share Posted April 27, 2010 Totally cracking up! Jim, I read it, didn't see your mistake and knew what you meant. Geesh, maybe we are all linked telepathically!Susie, yes, it was recommended to get it through LabCorp, rather than Quest because the ratios are easier to calculate. I wish I have also asked for Iron, Feriton, Chromium, and selenium. Oh, well, next time. Yes, to insurance. You want:Copper, serumZinc, plasma or serum (that's what is says on LabCorp report - no test #'s) thanks for this linda. i'm glad you caught it sooner rather than later. do you get serum levels through a regular lab? covered by insurance? xo susie Copper and Immune Function It has been well documented that adequate copper status is essential for normal functioning of the immune system in laboratory and domestic animals.47 For instance, not only has it been shown that the functioning of macrophages were decreased in severely copper deficient rats, but even marginally copper-deficient rats had impaired immune functioning.48 Interestingly, immune function was significantly impaired at dietary copper levels that didn't seem to decrease tissue copper or the activity of red blood cell Cu,Zn-superoxide dismutase (SOD).49 However, neutrophil SOD-activity and neutrophil function was significantly diminished, suggesting that immune function may be more sensitive to diets low in copper than standard measures of copper status. It was also found that immune impairment could be detected as soon as one week after the initiation of a diet low or marginal in copper, and the addition of adequate copper reversed the immune suppression within one week of supplementation. The authors concluded that, " ...the adverse effects of inadequate copper intake on neutrophil activity occur rapidly and are readily reversed by dietary copper repletion. " Additionally, it has been demonstrated that copper deficiency reversibly impairs DNA synthesis in activated T-cells by limiting interleukin 2 activity up to 50%, and this was reversible with copper supplementation.50 Because of this sensitivity to copper status at levels of intake that have little effect on other indicators of copper status, immune system cells have been suggested to be a readily accessible and copper-status sensitive population of cells for the assessment of copper status.51 http://www.oralchelation.com/technical/copper1.htm Quote Link to comment Share on other sites More sharing options...
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