Guest guest Posted December 16, 2011 Report Share Posted December 16, 2011 hello all I just thought I would like to share this with you - I was asked to send a list of possible herbs that I might use for a 10 year old child with RA whose parents are being told that he must go on methotrexate. The parents have been trying to keep him off methotrexate and just on herbs and diet, but I had only seen him for 3 weeks before the paediatrics team stepped in so not long enough to have any real effects. I had already been told that he couldn't have tinosporia and gotu cola, and so I sent them this list, and this is what I got back...... here is the information from the Pharmacy team As there is currently no safety data of any herbal medicine in children, the team would have to actively discourage the use of herbs for this child. However, this is the relevant information found on the different supplements. Milk Thistle: This has an effect on the immune system, according to one report only; it has Anti-TNF activity (it has an effect on a specific cell involved in the normal inflammatory process, which in children with arthritis is excessive). There are no human data for long-term safety. It is widely used to protect the liver. One study in children being treated for acute lymphoblastic leukaemia showed some beneficial effects on liver function. Boswellia (known as Indian incense): This has anti-inflammatory properties. There are no human data on safety for use beyond 12 weeks. Commiphora (Myrrh): This has been used as an immunostimulant, but its efficacy is unproven. If myrrh has immunostimulant properties, it would counteract the effect of methotrexate. Turmeric, this is a very widely used curry spice, which may have anti-inflammatory properties. It is likely to be safe. Filipendula (Meadowsweet): This contains salicylates and is therefore contra-indicated in children due to the risk of them developing Reye’s syndrome. Betula (Birch): This has diuretic properties. The effect on excretion of methotrexate is unknown, but in general diuretics do not increase the toxicity of methotrexate. Dioscoria (Wild Yam): This has oestrogenic properties (having an action similar to that of an oestrogen) and should not be administered to children. Chamomile: This may also have oestrogenic effects and should not be administered to children Liquorice: This has anti-inflammatory effects. It can cause fluid retention and hypertension, it may reduce testosterone levels. It should not be administered to children in large doses. Withania (Ashwagandha): May have immunostimulant properties and could counteract the effect of methotrexate. Sorry this isn’t more positive, but as I said although we like to support parents in their choices for their child’s health needs, we are also bound in giving advice that is supported with cold, hard scientific proof. I hope this information is somewhat useful, and a way forward can be found. I'm going to use milk thistle, liquorice, boswellia and turmeric as they seem to have grudgingly ok'd these. I don't really think it is worth challenging them - but chamomile - CI in children because it is oestrogenic !!! Just thought you might like to see it though - any other ideas about herbs to consider would be welcomed.His digestion is already pretty good. all the best for Solstice, Christmas and New year -- Herbert Herbalist and allergy therapist 15 Queens St Spooner Row Norfolk NR18 9JU 01953 603056 www.christineherbert.co.uk Quote Link to comment Share on other sites More sharing options...
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