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Satraplatin

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It is certainly worth everyone keeping an eye out for. Pt has been used for

donkeys years as a non-toxic anti-cancer agent. As it cannot be patented it

has not received the 'scientific' attention it probably deserves. Sammy.

Satraplatin

Has any group member had any personal experience of Satraplatin, an orally

administered platinum substance currently on trial in several countries for

the treatment of CaP?

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> 50% decrease in PSA was seen in 2/23 (8.7%) on the prednisone alone arm

and in 9/27 (33.3%) in the JM 216 + prednisone arm (P=0.046). Toxicity was

minimal in both arms; 1 patient on each arm died due to stomach perforation,

most likely related to prednisone. Compliance to treatment was excellent.

(Table) Analysis lacks power as only 50 pts were entered.

As Popeye says, it is a case of " You pays your money and you takes your

choice " .

Still, it seems strange to me that a study should be selecting people near

death's door to determine efficacy. I mean, what are they expecting MIRACLES

? Indeed, that may explain why the study was dropped. A cure that benefits

only 10% of a population may not be economical enough to develop.

Sammy.

RE: Satraplatin[scanned]

>

>

> Have a look at the website below.

> It appears that the company has stopped the trials but unclear as to why.

> Query if it was beneficial.

>

>

http://www.asco.org/ac/1,1003,_12-002489-00_18-002003-00_19-00100833,00.asp

>

>

>

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I think that the dosage may be different (lower) and from what I know of the tests in the Uk hospital I know about the men are not at death's door.

It may be worth comparing dosages.

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