Re: 200 microgram/day L-Selenomethionine decreases TPOAb titers effectively.

[Guest guest]

Thank you for sending all this. This is great info.

200 microgram/day L-Selenomethionine decrases TPOAb titers effectively. More Than 50% of patients response Se theraphy. It takes 6-12 mo. No need for additional E, A vitamin. Se therapy also works in pregnant Hashi patients.

U do not need to detect your serum Se levels because only one tablet of Se can saturate serum levels but tissue concentration requires months.

If your TPOAb titer is high, probably your response will be better.

More than 20 articles from 5 different countries. There is only two negative studies. Both of them had errors in their methodology. U can access the links below.

Free full text From Turks:

http://joe.endocrinology-journals.org/content/190/1/151.long

From Greaks:

http://www.ncbi.nlm.nih.gov/pubmed/12656658

Se works in postpartum thyroiditis too (From Italians):

http://www.ncbi.nlm.nih.gov/pubmed/17284630

From Greeks:

http://www.ncbi.nlm.nih.gov/pubmed/17696828

From Germans:

http://www.ncbi.nlm.nih.gov/pubmed/11932302

A meta analyses:

http://www.ncbi.nlm.nih.gov/pubmed/20883174

Karakanikas' study:

http://www.ncbi.nlm.nih.gov/pubmed/18302514

I've already posted the link of answers to Karanikas.

[Guest guest]

Dr O,

I am happy to go along with Selenium supplementation. But given that the usual

recommended maximum from, for example, the UK's NHS, is around a third of the

200 mcg you suggest, do you advise that long term? Or only until the antibody

levels drop? Or for a few weeks or months until any possible low selenium level

has recovered?

My feeling is that I would be reasonably happy to take up to 100 mcg per day

long term, but am very wary of more than that. After all, that is 100 mcg on top

of what we are already getting in our diets.

Are there any studies on this?

Rod

>

> 200 microgram/day L-Selenomethionine decrases TPOAb titers effectively. More

Than 50% of patients response Se theraphy. It takes 6-12 mo. No need for

additional E, A vitamin. Se therapy also works in pregnant Hashi patients.

> U do not need to detect your serum Se levels because only one tablet of Se can

saturate serum levels but tissue concentration requires months.

> If your TPOAb titer is high, probably your response will be better.

> More than 20 articles from 5 different countries. There is only two negative

studies. Both of them had errors in their methodology. U can access the links

below.

>

> Free full text From Turks:

> http://joe.endocrinology-journals.org/content/190/1/151.long

>

> From Greaks:

> http://www.ncbi.nlm.nih.gov/pubmed/12656658

>

> Se works in postpartum thyroiditis too (From Italians):

> http://www.ncbi.nlm.nih.gov/pubmed/17284630

>

> From Greeks:

> http://www.ncbi.nlm.nih.gov/pubmed/17696828

>

> From Germans:

> http://www.ncbi.nlm.nih.gov/pubmed/11932302

>

> A meta analyses:

> http://www.ncbi.nlm.nih.gov/pubmed/20883174

>

> Karakanikas' study:

> http://www.ncbi.nlm.nih.gov/pubmed/18302514

>

> I've already posted the link of answers to Karanikas.

>

[Guest guest]

what about us with Hashi's and reverse T3 problem ?, apparently it can get worse when you supplement with Selenium.I have high antibodies x nearly 2 years and didn't make any difference taking it so i stop when i found out I had reverse T3.To be honest I am fearful to try again I only take once a week or so.M.To:

Thyroiditis Sent: Thursday, 30 June 2011 1:49 AMSubject: Re: 200 microgram/day L-Selenomethionine decreases TPOAb titers effectively.

Thank you for sending all this. This is great info.

200 microgram/day L-Selenomethionine decrases TPOAb titers effectively. More Than 50% of patients response Se theraphy. It takes 6-12 mo. No need for additional E, A vitamin. Se therapy also works in pregnant Hashi patients.

U do not need to detect your serum Se levels because only one tablet of Se can saturate serum levels but tissue concentration requires months.

If your TPOAb titer is high, probably your response will be better.

More than 20 articles from 5 different countries. There is only two negative studies. Both of them had errors in their methodology. U can access the links below.

Free full text From Turks:

http://joe.endocrinology-journals.org/content/190/1/151.long

From Greaks:

http://www.ncbi.nlm.nih.gov/pubmed/12656658

Se works in postpartum thyroiditis too (From Italians):

http://www.ncbi.nlm.nih.gov/pubmed/17284630

From Greeks:

http://www.ncbi.nlm.nih.gov/pubmed/17696828

From Germans:

http://www.ncbi.nlm.nih.gov/pubmed/11932302

A meta analyses:

http://www.ncbi.nlm.nih.gov/pubmed/20883174

Karakanikas' study:

http://www.ncbi.nlm.nih.gov/pubmed/18302514

I've already posted the link of answers to Karanikas.

[Guest guest]

,

I believe the studies show that Se helps the majority just over half the

patients so it is reasonable it didn't help you. What form of Se did you take?

Also, good you stopped the Se as type I deiodinase is the major enzyme in the

liver, kidneys, and skeletal muscle; it can carry out both 5'- and

5-deiodination of T4 to produce either T3 or rT3.

I had a similar experience, my iodine was very low maybe due to a severe crash

in 2004. I found that iodine and Se work together in the body and thus need to

be balanced. If iodine is high supplementing with Se is usually helpful

according to studies. However, if both Se and iodine are low only supplementing

with one (Se) made me feel very much worse. I found this to be true for others

as well.

Supplemental iodine is controversial in Hashi patients; it helps some and others

not so much. I take both daily and can feel the difference in lower energy/ more

fatigued and sluggish if I skip a few days.

HTH,

~Bj

>

>  

> >200 microgram/day L-Selenomethionine decrases TPOAb titers effectively. More

Than 50% of patients response Se theraphy. It takes 6-12 mo. No need for

additional E, A vitamin. Se therapy also works in pregnant Hashi patients.

> >U do not need to detect your serum Se levels because only one tablet of Se

can saturate serum levels but tissue concentration requires months.

> >If your TPOAb titer is high, probably your response will be better.

> >More than 20 articles from 5 different countries. There is only two negative

studies. Both of them had errors in their methodology. U can access the links

below.

> >

> >Free full text From Turks:

> >http://joe.endocrinology-journals.org/content/190/1/151.long

> >

> >From Greaks:

> >http://www.ncbi.nlm.nih.gov/pubmed/12656658

> >

> >Se works in postpartum thyroiditis too (From Italians):

> >http://www.ncbi.nlm.nih.gov/pubmed/17284630

> >

> >From Greeks:

> >http://www.ncbi.nlm.nih.gov/pubmed/17696828

> >

> >From Germans:

> >http://www.ncbi.nlm.nih.gov/pubmed/11932302

> >

> >A meta analyses:

> >http://www.ncbi.nlm.nih.gov/pubmed/20883174

> >

> >Karakanikas' study:

> >http://www.ncbi.nlm.nih.gov/pubmed/18302514

> >

> >I've already posted the link of answers to Karanikas.

> >

> >

>