gluten and neurological conditions - including hypotonia, dev delays, ADHD, etc.

[Guest guest]

I've been poking around the medical research literature for more info

to give to some of my family members regarding the neurological

connection to gluten intolerance and Celiac disease. I came across

this article and thought many of you may be interested in the info as

it makes reference to Down's syndrome, hypotonia, epileptic

conditions, chronic headaches, learning disorders, etc.

The entire article can be found here:

http://pediatrics.aappublications.org/cgi/reprint/113/6/1672

(and I'll try to post it to the files section)

Here's the abstract/summary:

--------------------------------------------------------------

Pediatrics. 2004 Jun;113(6):1672-6.

Range of neurologic disorders in patients with celiac disease.

Zelnik N, Pacht A, Obeid R, Lerner A.

Department of Pediatrics, Carmel Medical Center, The Bruce Rappaport

Faculty of Medicine, Technion-Israel Institute of Technology, Haifa,

Israel. nzelnik@...

OBJECTIVE: During the past 2 decades, celiac disease (CD) has been

recognized as a multisystem autoimmune disorder. A growing body of

distinct neurologic conditions such as cerebellar ataxia, epilepsy,

myoclonic ataxia, chronic neuropathies, and dementia have been

reported, mainly in middle-aged adults. There still are insufficient

data on the association of CD with various neurologic disorders in

children, adolescents, and young adults, including more common and

" soft " neurologic conditions, such as headache, learning disorders,

attention-deficit/hyperactivity disorder (ADHD), and tic disorders.

The aim of the present study is to look for a broader spectrum of

neurologic disorders in CD patients, most of them children or young

adults. METHODS: Patients with CD were asked to fill in a

questionnaire regarding the presence of neurologic disorders or

symptoms. Their medical charts were reviewed, and those who were

reported as having neurologic manifestations underwent neurologic

examination and brain imaging or electroencephalogram if required.

Their neurologic data were compared with that of a control group

matched for age and gender. RESULTS: Patients with CD were more prone

to develop neurologic disorders (51.4%) in comparison with control

subjects (19.9%). These disorders include hypotonia, developmental

delay, learning disorders and ADHD, headache, and cerebellar ataxia.

Epileptic disorders were only marginally more common in CD. In

contrast, no difference was found in the prevalence of tic disorders

in both groups. Therapeutic benefit, with gluten-free diet, was

demonstrated only in patients with transient infantile hypotonia and

migraine headache. CONCLUSION: This study suggests that the

variability of neurologic disorders that occur in CD is broader than

previously reported and includes " softer " and more common neurologic

disorders, such as chronic headache, developmental delay, hypotonia,

and learning disorders or ADHD. Future longitudinal prospective

studies might better define the full range of these neurologic

disorders and their clinical response to a gluten-free diet.

PMID: 15173490 [PubMed - indexed for MEDLINE]

-----------------------------------------------------

[Guest guest]

Thank you for this!! I find it very interesting also that the gluten free theory is almost identical to the fungal free diet that is helping so many people recover from so many medical conditions such as...ms, high blood preasure, "Cancer(is fungus)", constipation, even diabetes, etc etc. We seen big improvements with our son also when we added the antifungals. I believe the antifungals are a big part of our son no longer having seizures(had 1 only now in a year and a half and suspect it was from spider bite). I do have concerns that he is on oatmeal. This has been part of his pureed routine for years, it adds substance to his food/pureed. It is almost powder form and so no bulk, but do wonder about the oats(possible gluten/fungal issue). Seems there is some controversy on this one. Do you have any thoughts on it.

Jennie<>< I also want to mention we have seen neuro improvements in the last year or so such as more verbal, no siezures, interacting/starting to act like a typical toddler now:)(9yr old), recovers from virus's on own now etc etc. I really suspect the antifungal theory(which is also gluten free) is healing my son in so many ways!

Subject: gluten and neurological conditions - including hypotonia, dev delays, ADHD, etc.To: miralax Date: Friday, January 23, 2009, 9:05 PM

I've been poking around the medical research literature for more infoto give to some of my family members regarding the neurologicalconnection to gluten intolerance and Celiac disease. I came acrossthis article and thought many of you may be interested in the info asit makes reference to Down's syndrome, hypotonia, epilepticconditions, chronic headaches, learning disorders, etc.The entire article can be found here:http://pediatrics. aappublications. org/cgi/reprint/ 113/6/1672(and I'll try to post it to the files section)Here's the abstract/summary:------------ --------- --------- --------- --------- --------- -Pediatrics. 2004 Jun;113(6):1672- 6.Range of neurologic disorders in patients with celiac disease.Zelnik N, Pacht A, Obeid R, Lerner A.Department of Pediatrics, Carmel

Medical Center, The Bruce RappaportFaculty of Medicine, Technion-Israel Institute of Technology, Haifa,Israel. nzelniknetvision (DOT) net.ilOBJECTIVE: During the past 2 decades, celiac disease (CD) has beenrecognized as a multisystem autoimmune disorder. A growing body ofdistinct neurologic conditions such as cerebellar ataxia, epilepsy,myoclonic ataxia, chronic neuropathies, and dementia have beenreported, mainly in middle-aged adults. There still are insufficientdata on the association of CD with various neurologic disorders inchildren, adolescents, and young adults, including more common and"soft" neurologic conditions, such as headache, learning disorders,attention-deficit/ hyperactivity disorder (ADHD), and tic disorders.The aim of the present study is to look for a broader spectrum ofneurologic disorders in CD patients,

most of them children or youngadults. METHODS: Patients with CD were asked to fill in aquestionnaire regarding the presence of neurologic disorders orsymptoms. Their medical charts were reviewed, and those who werereported as having neurologic manifestations underwent neurologicexamination and brain imaging or electroencephalogra m if required.Their neurologic data were compared with that of a control groupmatched for age and gender. RESULTS: Patients with CD were more proneto develop neurologic disorders (51.4%) in comparison with controlsubjects (19.9%). These disorders include hypotonia, developmentaldelay, learning disorders and ADHD, headache, and cerebellar ataxia.Epileptic disorders were only marginally more common in CD. Incontrast, no difference was found in the prevalence of tic disordersin both groups. Therapeutic benefit, with gluten-free diet, wasdemonstrated only in patients with

transient infantile hypotonia andmigraine headache. CONCLUSION: This study suggests that thevariability of neurologic disorders that occur in CD is broader thanpreviously reported and includes "softer" and more common neurologicdisorders, such as chronic headache, developmental delay, hypotonia,and learning disorders or ADHD. Future longitudinal prospectivestudies might better define the full range of these neurologicdisorders and their clinical response to a gluten-free diet.PMID: 15173490 [PubMed - indexed for MEDLINE]------------ --------- --------- --------- --------- -----