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ly, no, I can't help but my husband, 72, has had the same orthostatic

problem for several yrs. I'd have to look up in my notes just how long it has

been, but I know it has been at least 5 yrs, perhaps more. We went through

a period where he had the same high numbers you mentioned and then the low

ones. He'd zonk out and collapse, fall, couldn't get up, etc. We tried all

sorts of meds through the yrs. and he is now only on Florinef, .lmg 2 times a

day and he is off of all Parkinson meds, which he had been on. He takes

Razadyne, for dementia and Seroquel at night. From what I know now, I truly

believe that there isn't a medicine that will turn things around... this is a

malfunctioning Autonomic Nervous System. It has truly done more to wreck our

lives than anything because you can't predict when the B. pressure will sky

rocket. Going from hot to cold or vice versa seems to trigger the low

readings,

or after a meal, after a bowel movement, after exertion, when thirsty, to

name a few. All I can say to you is that he had been on Sinemet and Namenda,

which are known to affect the blood pressure and now that he is off of them and

only taking the Florinef, he is stabilized. Whether or not this is a

coincidence, a spontaneous occurrence, or the Florinef, I don't know. He wears

Futuro stockings and his legs are elevated most of the time. I certainly can

identify, that is for sure and I do hope that your husband can get the

appropriate help. If you have other questions, I'd be glad to answer.

Arlene

************************************** See what's free at http://www.aol.com.

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oh sweetie,

i understand the orthostatic bp that is what my dad unofficially died from his

bp just started dropping leveled out for an hour and then started dropping again

until he died, he was like this for only 6 months, but i know my dad as well,

he had promised his mom that he wouldnt die before her she died in aug 2005 and

he gave up less than one month later, giving his sister enough time to grieve

for her before he joined her.

i wasnt there due to a 'misunderstanding' from teh nurse that called me but one

of dads favorite nurses were there when daddy died thankfully and she said he

went very peacefully pointing to teh heavens saying mommy, so i am sure my

grandmother waited for him to jion her before finding her husband/my dad's dad.

the official cause of death was lbd on teh death certificate even though we

didnt have an autopsy but his md the nursing home md and the neuro all agreed

taht dad was symptomatic for lbd.

good luck adn sorry to tell you my tale. hugs, sharon a-m

---- mimiartsy wrote:

My husband Mike has been sent back to the hospital with BP 250 laying

down and 70/50 when standing...he got out of one hospital Wed and was

sent back to rehab...I got a call from rehab and they told me he was

suicidal and tried to jump out a window..he also struck someone and

was exhibiting violent behavior...they gave him a one on one aide and

called me in to calm him down....he is now back in the hospital with a

one on one and is confined to bed because of his BP..he also has no

strength and can not walk..he is paranoid ,confused,delusional and can

not be left alone...I was told that it comes to a point where the meds

can not help control the BP anymore??????????? ne has not been out of

the hospital and rehab for over a month....Does anyone know where we

are with this??? meg {mike dx 1/2005LBD is orthostatic and has

CDiff..we know it goes back to 2003 in hind sight and has REM disorder

forev

--

I am daugher of Leonard, diagnosed May 2004, probably had lbd since 1993,.Dad

had a serious fall in 7/05 causing him to hav hip surgery .After that he

developed aspiration pneumonia 7/05 with pulmonary embolyis, which he almost

died from. He had a 2nd bout of aspiration pneumonia and uti 8/05. He died when

his blood pressure fluctuations started dropping without coming back up on

9/25/05,

may he rest in peace with his mom and dad,

a smile a day keeps the meanies away

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  • 1 month later...
Guest guest

The other med besides Carbidopa/levodopa (Sinemet) that Dr. Boeve

suggests is Pramipexole (AKA Miraplex and Sifrol.)

You can find dosage recommendations here:

http://www.lewybodydementia.org/docs/DLB-BoeveContinuum04.pdf

-----

I did a quick search on our message board about Miraplex and found

this post:

http://health.groups.yahoo.com/group/LBDcaregivers/message/12528

----

Also found this:

What other drugs will affect risperidone?

Before taking this medication, tell your doctor if you are taking any

of the following medicines:

carbamazepine (Carbatrol, Tegretol);

phenytoin (Dilantin);

phenobarbital (Luminal, Solfoton);

clozapine (Clozaril);

fluoxetine (Prozac) or paroxetine (Paxil);

rifampin (Rifadin, Rimactane, Rifater); or

medicines used to treat Parkinson's Disease such as levodopa (Dopar,

Larodopa, Sinemet, Atamet, others), bromocriptine (Parlodel, others),

pergolide (Permax), pramipexole (Mirapex), or ropinirole (Requip).

If you are using any of these drugs, you may not be able to use

risperidone, or you may need dosage adjustments or special tests

during treatment.

There may be other drugs not listed that can affect risperidone. Tell

your doctor about all the prescription and over-the-counter

medications you use. This includes vitamins, minerals, herbal

products, and drugs prescribed by other doctors. Do not start using a

new medication without telling your doctor.

----

One side effect of Miraplex - extreme sleepiness

http://tinyurl.com/2wzyja

----

Hope the above helps...

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Guest guest

Also look into Neupro...

FDA Approves Neupro Patch for Treatment of Early Parkinson's Disease

May 9, 2007

The U.S. Food and Drug Administration (FDA) today announced the

approval of Neupro (rotigotine transdermal system), a skin patch

designed to treat symptoms of early Parkinson's disease.

Rotigotine is a drug not previously approved in the United States.

Neupro is the first transdermal patch approved for the treatment of

symptoms of Parkinson's disease.

Parkinson's disease, which belongs to a group of conditions called

motor system disorders, results from the loss of dopamine-producing

brain cells. Rotigotine, a member of the dopamine agonist class of

drugs, is delivered continuously through the skin (transdermal) using

a

silicone-based patch that is replaced every 24 hours. A dopamine

agonist works by activating dopamine receptors in the body, mimicking

the effect of the neurotransmitter dopamine.

Read more:

http://www.fda.gov/bbs/topics/NEWS/2007/NEW01631.html

Also read this:

Rotigotine As Levodopa Adjunct Is Effective In Advanced Parkinson's

Disease

May 3, 2007

Transdermal rotigotine (Neupro) up to doses of 8 and 12 mg/day as

adjunctive therapy to levodopa significantly decreases " off time " in

patients with advanced Parkinson's disease, according to phase III

data presented at the 59th Annual Meeting of the American Academy of

Neurology (AAN).

A. LeWitt, MD, professor of neurology at Wayne State University

in Milwaukee, Wisconsin, reported results in 351 patients with

advanced idiopathic Parkinson's disease who had been randomized to

placebo or two target doses of rotigotine (up to either 8 mg/24h or

12mg/24h) for up to seven months. Rotigotine is a non-ergolinic

dopamine receptor agonist available as a patch for once-daily use.

Read More:

http://www.medicalnewstoday.com/healthnews.php?newsid=69814

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Guest guest

>

> Jackie,

>

> I think Sinemet is for the PD and if I remember correctly the

dementia and PD drugs fight. Most people talk about getting just the

right amount of both to make them work. Maybe someone here can

help. Or go to the " links " at the bottom and check some of the links

about drugs.

>

> You can also go to the " messages " at the bottom of this and go into

Yahoo and do a " search " in messages.

>

> I didn't need to use this drug, but I do remember others saying it

took a while to get a " right " balance.

>

> Hugs,

>

> Donna R

>

> Caregave for Mom (after I brought her from WI to MI) for 3 years

and 4th year in a nh.

> She was almost 89 when she died in '02. No dx other than mine.

>

>

> Help

>

> Okay everyone I finally feel comfortable enough to write more often

> and now ask for help.I know this has been addressed before but at

the

> time it didn't pertain to Hubby.He has been on Exelon since dx'd.It

> took over a year to get him up to 3mg 2xd.Risperdal(I know Iknow)

0.5

> 2-3xd.It works great for him.Before he took it his delusions were

> HORRIBLE and I do mean horrible.Now no delusions and no

> hallucinations.His neurologists wants him on Sinemet 25/100 1/2 up

to

> 3xd.I'm still trying after almost 6 months to get him on the second

> half.I feel like it makes him vacant.Like there isn't always

someone

> home.Does anyone have any alternitive to the sinemet that I might

ask

> for.I know you can't subscribe but you can all give me your expert

> opinions.

> He is also on Lexapro 20mg 1xd to keep away the boohoos.Hyzaar for

> H.B.P.and Lovastatin for Cholesteral.

> His symptoms,now that I look back,started 12 yrs ago.Proceeded to

get

> worse after 6 by-passes in 2000.Really came to a head after 2

> Cataract surgeries and a Prostate procedure in 2004.Finally Dx'd

with

> Vascular dementia from 35 yrs of Diabetes,Secondary Parkinsonism

and

> L.B.D.

> Now that we know what he has and are treating it it is a more

gentle

> roller coaster.

> Thank you again for all the love,hugs,support and information.

>

> Jackie

>

>

> Thank you Donna,

It is so much easier to talk to someone who has been there or is

there.Sometimes even the Dr's don't have as much knowledge as those

who are living it.At least when we get info from all we can go to our

Appt's armed with good information.

Thank you again,

Jackie

>

>

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  • 1 year later...

First the PEG is a synthetic form of pure poisen as far as im

concerned. Tell her to insist on magnesium citrate for cleanout, this

was what was always used for cleanouts befor the horrid PEG came

along. I believe that the PEG destroys the nerve cells in the

intestinal tract and this is the cause for intestinal desensitising

(sp) and the need for more and more over time. Even 1 cleanout with

the PEG is dangerous, we learned this first hand. The hospital

started the PEG and then by the next day was admitted into ICU,

apparently the PEG can cause potasium(electrolytes) drops so low that

the heart starts to have problems and they can actually have a heart

attack. When my sons potasium levels was checked to see what the

levels was befor the PEG cleanout, they was normal. There is no

reason the magnesium citrate cant be used(plus I fell the magnesium

citrate cleanse is a good start to the gi healing process). It is

more hassle due to taste, but the PEG isnt worth it. Jennie<><

>

>

> Subject: Help

> To: miralax

> Date: Friday, January 16, 2009, 1:34 PM

>

>

>

>

>

>

> My daughter wants to give my Grandson Miralax to " clean " him out.

> Please help me with why she shouldn't. I know miralax is not good

for

> anyone, but I need to tell her why.

>

> Thanks

> Deb

>

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  • 8 months later...

I wondered if anyone could help/advise with any experience they may have.

I have been seeing a 72 year old lady for about four weeks now. She

presented with eczema type rash/patches on the front of one shin covering about

65% of the shin. It was red, hot and itchy - wasn't infected and hadn't

really " broken out " or was weepy. The other leg had only two or three

patches of dry eczema type patches but only tiny areas. She had some other dry

areas on her low back but nothing else anywhere else. She is very

fit/active/ walks three to four miles daily, still does part time volunteer

work,

slim build, a bit of a worrier, on no medication but various supplements

which i've checked and gone through. No high blood pressure or any other

medical conditions. Her husband had a stroke a year ago so she has had a

fairly

stressful year, which is now getting better.

I treated her with a skin wash, internal mix and a cream. She returned

after two weeks with a great improvement, the back had almost completely

gone and the bad leg was less red, the cracked areas had healed and the

itching/heat was much improved. I continued the treatment and today she

returned

saying that week three showed a continued improvement then last week

suddenly became dramatically worse.

On examination of her leg today it is red, hot, fiery, she has ankle

swelling and the front of her whole shin is red rather than the patchy areas.

I've seen a similar situation with another patient who actually had

diabetes and her blood sugar levels were wildly out of control but i've done a

urinalysis on this lady and it showed normal. I don't have my prescription

book to hand to list my herbs but given that there has been three weeks of

improvement I didn't think that they would be the cause. She said nothing

has changed in her diet/lifestyle - she has done more walking but that's

all. Has anyone any advice? I'm concerned about infection so intend to make

sure that the area does not become infected. She is still very keen to

work with herbs rather than steriods. Any advice would be gratefully received.

Jean

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