Re: new study - going GF doesn't slow Hashis

[Guest guest]

I discussed this study with some of the top folks in the gluten research world (Dr Fasano, Dr Green, etc) and I've read the study in detail. I've also emailed with the lead researcher from the study. There are about a dozen other studies showing that a gluten-free diet helps Hashimoto's in those with gluten issues. This study has many flaws including the fact that it only included something like 27 patients - not enough to make any definitive conclusions. Also, they only followed patients for one year. That may not be enough time to pick up a benefit in thyroid function. There's also questions about how gluten-free the patients truly were. And the comparison group were normal patients when the comparison group should ideally have been Celiacs on a gluten diet. So overall, the literature still supports the benefits of a gluten-free diet in those with autoimmune thyroid disease and gluten issues. Whether it helps autoimmune thyroid patients without gluten issues is an unanswered question. Sent from my BlackBerry® smartphone with SprintSpeedSender: Thyroiditis Date: Sun, 15 Jul 2012 01:59:22 -0000To: <Thyroiditis >ReplyTo: Thyroiditis Subject: new study - going GF doesn't slow Hashis This was referenced in my recent issue of " Living Without " (gluten-free magazine). The study was published in the Scandinavian Journal of Gastroenterology. Its main conclusion was that while going gluten-free is important for many Hashis patients, being GF does not appear to slow or reverse autoimmune thyroid disease. Subjects with Hashis saw their TPO-ab titers continue to rise after being on a strict gluten-free diet for a year. I have to say this confirms my experience - I wouldn't start on gluten again for the world, but my thyroid dosage needs have gone up, not down, since starting my GF diet. I suspect that gluten could trigger Hashis, but if it does it sets off a reaction that is not suppressed when gluten is removed.Not sure, however, about the conclusion that Celiac folks are at increased risk for developing Hashis even if they eat a strict GF diet. Of course they should have their thyroids checked periodically, but that seems to be a bit of a leap, considering it doesn't sound like anyone *developed* Hashis during this study.http://www.deepdyve.com/lp/informa-healthcare/gluten-free-diet-and-autoimmune-thyroiditis-in-patients-with-celiac-tv6tYIgrTEhttp://www.livingwithout.com/issues/4_21/research_roundup_as12-2985-1.html

[Guest guest]

You make some good points about the number of patients, the control group, how

they controlled the diet, etc. This study was referenced in a couple of consumer

magazines, but I'm not able to read the whole study. Do you have links for the

other studies you mention?

1 year seems like a long time to see improvement in Hashis though. It's been 1.5

years for me. I haven't had my antibodies tested but my dosage is the same -

wavering between 88 and 100 the last several years.

>

> I discussed this study with some of the top folks in the gluten research world

(Dr Fasano, Dr Green, etc) and I've read the study in detail. I've also emailed

with the lead researcher from the study. There are about a dozen other studies

showing that a gluten-free diet helps Hashimoto's in those with gluten issues.

This study has many flaws including the fact that it only included something

like 27 patients - not enough to make any definitive conclusions. Also, they

only followed patients for one year. That may not be enough time to pick up a

benefit in thyroid function. There's also questions about how gluten-free the

patients truly were. And the comparison group were normal patients when the

comparison group should ideally have been Celiacs on a gluten diet. So overall,

the literature still supports the benefits of a gluten-free diet in those with

autoimmune thyroid disease and gluten issues. Whether it helps autoimmune

thyroid patients without gluten issues is an unanswered question.

>

> Sent from my BlackBerry® smartphone with SprintSpeed

>

> new study - going GF doesn't slow Hashis

>

> This was referenced in my recent issue of " Living Without " (gluten-free

magazine). The study was published in the Scandinavian Journal of

Gastroenterology. Its main conclusion was that while going gluten-free is

important for many Hashis patients, being GF does not appear to slow or reverse

autoimmune thyroid disease. Subjects with Hashis saw their TPO-ab titers

continue to rise after being on a strict gluten-free diet for a year.

>

> I have to say this confirms my experience - I wouldn't start on gluten again

for the world, but my thyroid dosage needs have gone up, not down, since

starting my GF diet. I suspect that gluten could trigger Hashis, but if it does

it sets off a reaction that is not suppressed when gluten is removed.

>

> Not sure, however, about the conclusion that Celiac folks are at increased

risk for developing Hashis even if they eat a strict GF diet. Of course they

should have their thyroids checked periodically, but that seems to be a bit of a

leap, considering it doesn't sound like anyone *developed* Hashis during this

study.

>

>

http://www.deepdyve.com/lp/informa-healthcare/gluten-free-diet-and-autoimmune-th\

yroiditis-in-patients-with-celiac-tv6tYIgrTE

>

> http://www.livingwithout.com/issues/4_21/research_roundup_as12-2985-1.html

>

>

>

[Guest guest]

Here are some of the studies supporting a gluten-free diet in patients with autoimmune thyroid disease.

1. Study (from Pediatrics) showing that antibodies against the thyroid and

pancreas disappear on a gluten-free diet.

http://www.ncbi.nlm.nih.gov/pubmed?term=Gluten-dependent%20diabetes-related%20an\

d%20thyroid-related%20autoantibodies%20in%20patients%20with%20celiac%20disease

2. Study (from Gastroenterology) showing that the greater the gluten exposure,

the higher the risk of autoimmune thyroid disease.

http://www.ncbi.nlm.nih.gov/pubmed/10419909

3. Here are two studies (including one from a Columbia group published in the

journal Thyroid) showing that gluten-related antibodies can bind to thyroid

follicles and the thyroid matrix suggesting a potential cause of Hashimoto's.

http://www.ncbi.nlm.nih.gov/pubmed/19014325

http://www.ncbi.nlm.nih.gov/pubmed/19352315

4. Here is a multicenter Italian study (from The American Journal of

Gastroenterology) of patients with thyroid disease and gluten-sensitive

enteropathy. One year of gluten-free diet associated with a dramatic

normalization in thyroid function while a gluten-rich diet was associated with

continued thyroid problems. Their conclusion was that "gluten withdrawal may

single-handedly reverse the (thyroid) abnormality".

http://www.ncbi.nlm.nih.gov/pubmed/11280546

5. Italian study (from The Journal of Pediatrics) showing that in patients with

gluten-sensitive enteropathy Hashimoto's, thyroid antibodies resolve with a

gluten-free diet.

http://www.ncbi.nlm.nih.gov/pubmed/10931424

6. This is an excellent comprehensive review article (from Endocrine Reviews)

about endocrine disease and gluten sensitivity. It says that most studies

suggest that gluten plays a direct role in Hashimoto's.

http://edrv.endojournals.org/content/23/4/464.full.pdf+html

7. Study (from Diabetes & Metabolism Research and Reviews) showing that

gluten-free diet prevented/delayed autoimmune pancreatic disease (type-1

diabetes) in mice.

http://www.ncbi.nlm.nih.gov/pubmed/10585617

8. This study (from The American Journal of Gastroenterology) presented

evidence that gluten is a trigger for antibodies against the thyroid and

pancreas.

http://www.ncbi.nlm.nih.gov/pubmed/10925978

9. Study (from Clinical Gastroenterology & Hepatology) showing that celiac

patients on gluten-free diet had less autoimmune disease in other organs (like

the thyroid) than those who ate gluten. Authors concluded that "gluten-free

diet has a protective effect on endocrine organs."

http://www.ncbi.nlm.nih.gov/pubmed/18255352

10. Study showing that among gluten sensitive patients the greater the gluten

exposure, the more significant the antibody response against the pancreas.

Authors concluded that "the development of antibodies against the pancreas is

associated with the length of the exposure to gluten."

http://www.ncbi.nlm.nih.gov/pubmed/15478300

11. Study showing that children with gluten sensitivity have less endocrine

autoimmune disease if they follow gluten-free diet.

http://www.ncbi.nlm.nih.gov/pubmed/15709993

12. Excellent summary article (from popular magazine) about the role of gluten

in autoimmune thyroid disease.

http://www.todaysdietitian.com/newarchives/110310p52.shtml

new study - going GF doesn't slow Hashis

>

> This was referenced in my recent issue of "Living Without" (gluten-free magazine). The study was published in the Scandinavian Journal of Gastroenterology. Its main conclusion was that while going gluten-free is important for many Hashis patients, being GF does not appear to slow or reverse autoimmune thyroid disease. Subjects with Hashis saw their TPO-ab titers continue to rise after being on a strict gluten-free diet for a year.

>

> I have to say this confirms my experience - I wouldn't start on gluten again for the world, but my thyroid dosage needs have gone up, not down, since starting my GF diet. I suspect that gluten could trigger Hashis, but if it does it sets off a reaction that is not suppressed when gluten is removed.

>

> Not sure, however, about the conclusion that Celiac folks are at increased risk for developing Hashis even if they eat a strict GF diet. Of course they should have their thyroids checked periodically, but that seems to be a bit of a leap, considering it doesn't sound like anyone *developed* Hashis during this study.

>

> http://www.deepdyve.com/lp/informa-healthcare/gluten-free-diet-and-autoimmune-thyroiditis-in-patients-with-celiac-tv6tYIgrTE

>

> http://www.livingwithout.com/issues/4_21/research_roundup_as12-2985-1.html

>

>

>

[Guest guest]

Does anyone have a full copy of the study? It seems to be behind Informa's pay wall so I would have to go to the uni library to access it. Two questions I have seeing a study of such a small cohort and short duration making a conclusion. Who sponsored the study and what are the 

relationships of the study authors with various companies, industries, professional societies etc. I am currently working on some research related to radiation exposure groups. There are some scientists who will purposely create a study to give an expected outcome. One recent study was by MIT that declared the nuclear disaster in Japan to be a non issue because they studied a very small group of mice for 5 weeks. The bulk of the existing studies show that is not true, and that this study was created to have a desired outcome based on other studies that prove a longer time frame shows negative outcomes. This is just one example. I have found tons of them, usually authored by a handful of the same doctors with industry ties and frequently admit that an industry with a " dog in the race " paid for the study. This is usually buried in the fine print towards the end. My point being that if an industry sees medical science threatening their industry through litigation or public opinion they have no problem paying for a rigged study.

 There are at least two university groups working on this issue because it has become such a problem.  Rigged studies happen more often than people think. Then they work to get it in the news. All people hear is " such and such is good for you, or won't hurt you etc " . The cell phone industry has done it. The corn production industry has done it over corn syrup. Without reading this new Hashi's study I don't know if that is the case here but small cohort and short duration just scream rigged study to me since that is frequently the sign of such in my research work. 

Foust

 

I discussed this study with some of the top folks in the gluten research world (Dr Fasano, Dr Green, etc) and I've read the study in detail. I've also emailed with the lead researcher from the study. There are about a dozen other studies showing that a gluten-free diet helps Hashimoto's in those with gluten issues. This study has many flaws including the fact that it only included something like 27 patients - not enough to make any definitive conclusions. Also, they only followed patients for one year. That may not be enough time to pick up a benefit in thyroid function. There's also questions about how gluten-free the patients truly were. And the comparison group were normal patients when the comparison group should ideally have been Celiacs on a gluten diet. So overall, the literature still supports the benefits of a gluten-free diet in those with autoimmune thyroid disease and gluten issues. Whether it helps autoimmune thyroid patients without gluten issues is an unanswered question.

Sent from my BlackBerry® smartphone with SprintSpeed

Sender: Thyroiditis

Date: Sun, 15 Jul 2012 01:59:22 -0000To: <Thyroiditis >ReplyTo: Thyroiditis

Subject: new study - going GF doesn't slow Hashis

 

This was referenced in my recent issue of " Living Without " (gluten-free magazine). The study was published in the Scandinavian Journal of Gastroenterology. Its main conclusion was that while going gluten-free is important for many Hashis patients, being GF does not appear to slow or reverse autoimmune thyroid disease. Subjects with Hashis saw their TPO-ab titers continue to rise after being on a strict gluten-free diet for a year.

I have to say this confirms my experience - I wouldn't start on gluten again for the world, but my thyroid dosage needs have gone up, not down, since starting my GF diet. I suspect that gluten could trigger Hashis, but if it does it sets off a reaction that is not suppressed when gluten is removed.

Not sure, however, about the conclusion that Celiac folks are at increased risk for developing Hashis even if they eat a strict GF diet. Of course they should have their thyroids checked periodically, but that seems to be a bit of a leap, considering it doesn't sound like anyone *developed* Hashis during this study.

http://www.deepdyve.com/lp/informa-healthcare/gluten-free-diet-and-autoimmune-thyroiditis-in-patients-with-celiac-tv6tYIgrTE

http://www.livingwithout.com/issues/4_21/research_roundup_as12-2985-1.html

-- Foustwww.SimplyInfo.org - The Fukushima ProjectCrowd sourced information research & analysis without focus on profit

SimplyInfo.org research team memberSimplyInfo.org technical team memberinfo@... - group emaillillymunster@... - 's direct email

Blog - Going Green In A Red State

[Guest guest]

I believe the author of the study emailed it to me. I'll look. Can PDF's be emailed to this yahoo group?Sent from my BlackBerry® smartphone with SprintSpeedSender: Thyroiditis Date: Sun, 15 Jul 2012 10:17:29 -0500To: <Thyroiditis >ReplyTo: Thyroiditis Subject: Re: new study - going GF doesn't slow Hashis Does anyone have a full copy of the study? It seems to be behind Informa's pay wall so I would have to go to the uni library to access it. Two questions I have seeing a study of such a small cohort and short duration making a conclusion. Who sponsored the study and what are the relationships of the study authors with various companies, industries, professional societies etc. I am currently working on some research related to radiation exposure groups. There are some scientists who will purposely create a study to give an expected outcome. One recent study was by MIT that declared the nuclear disaster in Japan to be a non issue because they studied a very small group of mice for 5 weeks. The bulk of the existing studies show that is not true, and that this study was created to have a desired outcome based on other studies that prove a longer time frame shows negative outcomes. This is just one example. I have found tons of them, usually authored by a handful of the same doctors with industry ties and frequently admit that an industry with a " dog in the race " paid for the study. This is usually buried in the fine print towards the end. My point being that if an industry sees medical science threatening their industry through litigation or public opinion they have no problem paying for a rigged study. There are at least two university groups working on this issue because it has become such a problem.  Rigged studies happen more often than people think. Then they work to get it in the news. All people hear is " such and such is good for you, or won't hurt you etc " . The cell phone industry has done it. The corn production industry has done it over corn syrup. Without reading this new Hashi's study I don't know if that is the case here but small cohort and short duration just scream rigged study to me since that is frequently the sign of such in my research work.  Foust I discussed this study with some of the top folks in the gluten research world (Dr Fasano, Dr Green, etc) and I've read the study in detail. I've also emailed with the lead researcher from the study. There are about a dozen other studies showing that a gluten-free diet helps Hashimoto's in those with gluten issues. This study has many flaws including the fact that it only included something like 27 patients - not enough to make any definitive conclusions. Also, they only followed patients for one year. That may not be enough time to pick up a benefit in thyroid function. There's also questions about how gluten-free the patients truly were. And the comparison group were normal patients when the comparison group should ideally have been Celiacs on a gluten diet. So overall, the literature still supports the benefits of a gluten-free diet in those with autoimmune thyroid disease and gluten issues. Whether it helps autoimmune thyroid patients without gluten issues is an unanswered question. Sent from my BlackBerry® smartphone with SprintSpeedSender: Thyroiditis Date: Sun, 15 Jul 2012 01:59:22 -0000To: <Thyroiditis >ReplyTo: Thyroiditis Subject: new study - going GF doesn't slow Hashis This was referenced in my recent issue of " Living Without " (gluten-free magazine). The study was published in the Scandinavian Journal of Gastroenterology. Its main conclusion was that while going gluten-free is important for many Hashis patients, being GF does not appear to slow or reverse autoimmune thyroid disease. Subjects with Hashis saw their TPO-ab titers continue to rise after being on a strict gluten-free diet for a year. I have to say this confirms my experience - I wouldn't start on gluten again for the world, but my thyroid dosage needs have gone up, not down, since starting my GF diet. I suspect that gluten could trigger Hashis, but if it does it sets off a reaction that is not suppressed when gluten is removed.Not sure, however, about the conclusion that Celiac folks are at increased risk for developing Hashis even if they eat a strict GF diet. Of course they should have their thyroids checked periodically, but that seems to be a bit of a leap, considering it doesn't sound like anyone *developed* Hashis during this study.http://www.deepdyve.com/lp/informa-healthcare/gluten-free-diet-and-autoimmune-thyroiditis-in-patients-with-celiac-tv6tYIgrTEhttp://www.livingwithout.com/issues/4_21/research_roundup_as12-2985-1.html-- Foustwww.SimplyInfo.org - The Fukushima ProjectCrowd sourced information research & analysis without focus on profitSimplyInfo.org research team memberSimplyInfo.org technical team memberinfo@... - group emaillillymunster@... - 's direct emailBlog - Going Green In A Red State

[Guest guest]

You can try e-mailing it. If that doesn't go through, you can post it in the

Files section on our group's site. Thanks.

>

> > **

> >

> >

> > ** I discussed this study with some of the top folks in the gluten

> > research world (Dr Fasano, Dr Green, etc) and I've read the study in

> > detail. I've also emailed with the lead researcher from the study. There

> > are about a dozen other studies showing that a gluten-free diet helps

> > Hashimoto's in those with gluten issues. This study has many flaws

> > including the fact that it only included something like 27 patients - not

> > enough to make any definitive conclusions. Also, they only followed

> > patients for one year. That may not be enough time to pick up a benefit in

> > thyroid function. There's also questions about how gluten-free the patients

> > truly were. And the comparison group were normal patients when the

> > comparison group should ideally have been Celiacs on a gluten diet. So

> > overall, the literature still supports the benefits of a gluten-free diet

> > in those with autoimmune thyroid disease and gluten issues. Whether it

> > helps autoimmune thyroid patients without gluten issues is an unanswered

> > question.

> > Sent from my BlackBerry® smartphone with SprintSpeed

> > ------------------------------

> > *

> > *Sender: * Thyroiditis

> > *Date: *Sun, 15 Jul 2012 01:59:22 -0000

> > *To: *<Thyroiditis >

> > *ReplyTo: * Thyroiditis

> > *Subject: * new study - going GF doesn't slow Hashis

> >

> >

> >

> > This was referenced in my recent issue of " Living Without " (gluten-free

> > magazine). The study was published in the Scandinavian Journal of

> > Gastroenterology. Its main conclusion was that while going gluten-free is

> > important for many Hashis patients, being GF does not appear to slow or

> > reverse autoimmune thyroid disease. Subjects with Hashis saw their TPO-ab

> > titers continue to rise after being on a strict gluten-free diet for a

> > year.

> >

> > I have to say this confirms my experience - I wouldn't start on gluten

> > again for the world, but my thyroid dosage needs have gone up, not down,

> > since starting my GF diet. I suspect that gluten could trigger Hashis, but

> > if it does it sets off a reaction that is not suppressed when gluten is

> > removed.

> >

> > Not sure, however, about the conclusion that Celiac folks are at increased

> > risk for developing Hashis even if they eat a strict GF diet. Of course

> > they should have their thyroids checked periodically, but that seems to be

> > a bit of a leap, considering it doesn't sound like anyone *developed*

> > Hashis during this study.

> >

> >

> >

http://www.deepdyve.com/lp/informa-healthcare/gluten-free-diet-and-autoimmune-th\

yroiditis-in-patients-with-celiac-tv6tYIgrTE

> >

> > http://www.livingwithout.com/issues/4_21/research_roundup_as12-2985-1.html

> >

> >

> >

> >

> >

>

>

>

> --

> * Foust*

> www.SimplyInfo.org - The Fukushima Project

> *Crowd sourced information research & analysis without focus on profit*

> SimplyInfo.org research team member

> SimplyInfo.org technical team member

> info@... - group email

> lillymunster@... - 's direct email

> Blog - Going Green In A Red State <http://houseoffoust.com/blog/>

>

[Guest guest]

Just fyi for the group, the study has been posted in our Files section.

> >

> > > **

> > >

> > >

> > > ** I discussed this study with some of the top folks in the gluten

> > > research world (Dr Fasano, Dr Green, etc) and I've read the study in

> > > detail. I've also emailed with the lead researcher from the study. There

> > > are about a dozen other studies showing that a gluten-free diet helps

> > > Hashimoto's in those with gluten issues. This study has many flaws

> > > including the fact that it only included something like 27 patients - not

> > > enough to make any definitive conclusions. Also, they only followed

> > > patients for one year. That may not be enough time to pick up a benefit in

> > > thyroid function. There's also questions about how gluten-free the

patients

> > > truly were. And the comparison group were normal patients when the

> > > comparison group should ideally have been Celiacs on a gluten diet. So

> > > overall, the literature still supports the benefits of a gluten-free diet

> > > in those with autoimmune thyroid disease and gluten issues. Whether it

> > > helps autoimmune thyroid patients without gluten issues is an unanswered

> > > question.

> > > Sent from my BlackBerry® smartphone with SprintSpeed

> > > ------------------------------

> > > *From: * " suuzin " <suuzin@>

> > > *Sender: * Thyroiditis

> > > *Date: *Sun, 15 Jul 2012 01:59:22 -0000

> > > *To: *<Thyroiditis >

> > > *ReplyTo: * Thyroiditis

> > > *Subject: * new study - going GF doesn't slow Hashis

> > >

> > >

> > >

> > > This was referenced in my recent issue of " Living Without " (gluten-free

> > > magazine). The study was published in the Scandinavian Journal of

> > > Gastroenterology. Its main conclusion was that while going gluten-free is

> > > important for many Hashis patients, being GF does not appear to slow or

> > > reverse autoimmune thyroid disease. Subjects with Hashis saw their TPO-ab

> > > titers continue to rise after being on a strict gluten-free diet for a

> > > year.

> > >

> > > I have to say this confirms my experience - I wouldn't start on gluten

> > > again for the world, but my thyroid dosage needs have gone up, not down,

> > > since starting my GF diet. I suspect that gluten could trigger Hashis, but

> > > if it does it sets off a reaction that is not suppressed when gluten is

> > > removed.

> > >

> > > Not sure, however, about the conclusion that Celiac folks are at increased

> > > risk for developing Hashis even if they eat a strict GF diet. Of course

> > > they should have their thyroids checked periodically, but that seems to be

> > > a bit of a leap, considering it doesn't sound like anyone *developed*

> > > Hashis during this study.

> > >

> > >

> > >

http://www.deepdyve.com/lp/informa-healthcare/gluten-free-diet-and-autoimmune-th\

yroiditis-in-patients-with-celiac-tv6tYIgrTE

> > >

> > > http://www.livingwithout.com/issues/4_21/research_roundup_as12-2985-1.html

> > >

> > >

> > >

> > >

> > >

> >

> >

> >

> > --

> > * Foust*

> > www.SimplyInfo.org - The Fukushima Project

> > *Crowd sourced information research & analysis without focus on profit*

> > SimplyInfo.org research team member

> > SimplyInfo.org technical team member

> > info@ - group email

> > lillymunster@ - 's direct email

> > Blog - Going Green In A Red State <http://houseoffoust.com/blog/>

> >

>