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This is a good constructive read for someone with brain cancer

http://www.amazon.co.uk/Anticancer-New-Life--Servan-Schreiber/dp/0718154290

Helen

Glioma

Dear All

I have a young lad of 22 coming to see me, diagnosed with a glioma in

the brainstem discovered while having a brainscan for drug testing. The

only treatment he has been offered is radiotherapy but he would rather

avoid this. He is otherwise healthy, but did mention a prior blow to the

head in this area, I am not sure how long ago. He has been advised that

he may have had the glioma for some time. He notices head pains on

first getting up in the morning and also has slight visual disturbances.

I was thinking first of anti-inflammatories and notice Boswellia has

previously been indicated on this list for glioma. I was considering

Turmeric and also Centella due to the past trauma. Would circulatory

herbs such as ginkgo be indicated? He reports that his symptoms improve

when he goes running. He is very keen to help himself and I understand

has changed his diet dramatically under the guidance of a nutritionist.

Are herbs likely to make an impact on this condition? I feel somewhat

out of my depth with this one and would appreciate any advice.

Many thanks

Verity

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Hi Verity,

Herbs can really help with glioma, but I have only ever used them in

conjunction with radiotherapy and sometimes temozolomide (working together

with the patient's oncologist).

I always use Boswellia for glioma, as it has been shown to have anti-brain

cancer activity as well as being an excellent LOX inhibitor. I always use a

tablet, as in my opinion, it works better than the tincture, and you can use

higher doses. The same for the turmeric.

Other than that I tend to use cerebral circulatory stimulants such as Ginkgo

or Bacopa, together with other anti-inflammatories such as Bupleurum and

Glycyrrhiza. I also use immunostimulants such as Astragalus, Uncaria and

Phytolacca, and adaptogens such as Withania.

McLeod wrote a good article in the BJP 5(4), 199, with a case study on

glioma.

Best wishes,

Chris

Dr J Etheridge

PhD MRSC MCPP CChem DoIC ARCS BSc(Hons) Chem BSc(Hons) Phyto

Integrated Cancer Specialist

Suite 7

22 Northumberland Avenue

London

WC2N 5AP

T: 0

F: 0

E: info@...

W: www.drchrisetheridge.co.uk <http://www.drchrisetheridge.co.uk/>

J Etheridge

PhD MCPP MRSC CChem DoIC ARCS BSc(Hons) Chem BSc(Hons) Phyto

Medical Herbalist

Cheshunt Clinic of Herbal Medicine

62 Roundmoor Drive

Cheshunt

Hertfordshire

EN8 9HQ

M: 0

E: info@...

W: <http://www.drchrisetheridge.co.uk/> www.drchrisetheridge.co.uk

_____

From: ukherbal-list [mailto:ukherbal-list ]

On Behalf Of Verity Bradbury

Sent: Thursday, May 28, 2009 5:19 PM

To: ukherbal-list

Subject: Glioma

Dear All

I have a young lad of 22 coming to see me, diagnosed with a glioma in

the brainstem discovered while having a brainscan for drug testing. The

only treatment he has been offered is radiotherapy but he would rather

avoid this. He is otherwise healthy, but did mention a prior blow to the

head in this area, I am not sure how long ago. He has been advised that

he may have had the glioma for some time. He notices head pains on

first getting up in the morning and also has slight visual disturbances.

I was thinking first of anti-inflammatories and notice Boswellia has

previously been indicated on this list for glioma. I was considering

Turmeric and also Centella due to the past trauma. Would circulatory

herbs such as ginkgo be indicated? He reports that his symptoms improve

when he goes running. He is very keen to help himself and I understand

has changed his diet dramatically under the guidance of a nutritionist.

Are herbs likely to make an impact on this condition? I feel somewhat

out of my depth with this one and would appreciate any advice.

Many thanks

Verity

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I have used the herbs you suggest. The Boswellia needs to be in a high dose - I

use Mediherb pills for this.

J Fidler, MCPP, (RH) AHG

Herbalist

________________________________

To: ukherbal-list

Sent: Thursday, May 28, 2009 12:27:16 PM

Subject: Re: Glioma

This is a good constructive read for someone with brain cancer

http://www.amazon. co.uk/Anticancer -New-Life- -Servan- Schreiber/

dp/0718154290

Helen

Glioma

Dear All

I have a young lad of 22 coming to see me, diagnosed with a glioma in

the brainstem discovered while having a brainscan for drug testing. The

only treatment he has been offered is radiotherapy but he would rather

avoid this. He is otherwise healthy, but did mention a prior blow to the

head in this area, I am not sure how long ago. He has been advised that

he may have had the glioma for some time. He notices head pains on

first getting up in the morning and also has slight visual disturbances.

I was thinking first of anti-inflammatories and notice Boswellia has

previously been indicated on this list for glioma. I was considering

Turmeric and also Centella due to the past trauma. Would circulatory

herbs such as ginkgo be indicated? He reports that his symptoms improve

when he goes running. He is very keen to help himself and I understand

has changed his diet dramatically under the guidance of a nutritionist.

Are herbs likely to make an impact on this condition? I feel somewhat

out of my depth with this one and would appreciate any advice.

Many thanks

Verity

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Hi,

whilst reading up on artemisinin for one of my patients, I came across

artemesinin being discussed for use with brain tumours several times.  It

appears to be particularly effective as, being both fat and water soluble, it

appears to be able to cross the blood-brain barrier well.  Synthetic analogues

of artemisinin such as artemeter may be even more effective as it is more fat

soluble, however, artemisinin is much easier to obtain and there is plenty of

info on protocols.

Good luck!

Gursewa Harrad. 

 

Dear All

I have a young lad of 22 coming to see me, diagnosed with a glioma in

the brainstem discovered while having a brainscan for drug testing. The

only treatment he has been offered is radiotherapy but he would rather

avoid this. He is otherwise healthy, but did mention a prior blow to the

head in this area, I am not sure how long ago. He has been advised that

he may have had the glioma for some time. He notices head pains on

first getting up in the morning and also has slight visual disturbances.

I was thinking first of anti-inflammatories and notice Boswellia has

previously been indicated on this list for glioma. I was considering

Turmeric and also Centella due to the past trauma. Would circulatory

herbs such as ginkgo be indicated? He reports that his symptoms improve

when he goes running. He is very keen to help himself and I understand

has changed his diet dramatically under the guidance of a nutritionist.

Are herbs likely to make an impact on this condition? I feel somewhat

out of my depth with this one and would appreciate any advice.

Many thanks

Verity

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Der Verity,

As we know it is difficult for any medicines to pass the brain barriers. i

have never treated any brain tumors. I found this article on the itnernet

and your patient may consider this approach which seems a better option than

Chemo.

Best of luck

Iria

*Glioma Brain Tumors*

*(Content updated June 2008)*

For years, researchers puzzled over an aggressive form of brain cancer. The

lethal glioma tumors often outsmart traditional cancer treatments such as

surgery, and quickly invade healthy brain tissue. But now an understanding

of the biological makeup and survival mechanisms of glioma tumors is helping

researchers develop methods that they hope will kill the cancer.

Brain tumors always have been one of the most devastating diseases because

they are so difficult to treat, much less cure. But now scientists are on

track toward finding what may be definitive treatments for the most virulent

of these tumors.

Most brain tumors develop from cancerous glial cells and are called gliomas.

Unlike other cancers, glioma tumors grow in the confined space inside the

head. In order to grow, most cancers push healthy cells aside, but due to

space constraints, glioma tumors must destroy normal brain cells. To kill

healthy nerve cells, glioma tumors release large quantities of the

neurotransmitter glutamate. Excess glutamate is toxic to neurons and causes

seizures in up to 80% of people with gliomas. Depending on the tumor's size

and location, other symptoms include paralysis, behavior changes and

dizziness.

A glioma tumor is particularly damaging because it tends to quickly sprout

and spread within the brain. Each year, approximately 18,000 Americans find

out that they have a glioma. Many die within 12 months.

Researchers have come closer to improving these odds by examining the

biology of glioma tumors in animals and humans. Studies are uncovering the

cancer's unique characteristics, including the mechanisms that help it

survive and spread throughout the brain.

The advances may help make the diagnosis less grim by leading to:

- Therapies that prevent gliomas from harming healthy brain cells.

- Methods that limit the spread of the cancer.

- Treatments that block the tumor's life-sustaining molecules.

Some scientists are devising therapies to limit the damage glioma tumors

inflict on healthy brain cells. To release glutamate, glial cells must first

import cystine, naturally formed from the fusion of two amino acids. The

drug sulfasalazine, which is normally used to treat inflammation in the

intestines, blocks cystine import and prevents glutamate release. Cystine is

a precursor for glutathione, an antioxidant that may help glioma tumors

survive chemotherapy. In animal studies, sulfasalazine reduced tumor size by

over 80%. Clinical trials using sulfasalazine to treat gliomas in humans

will begin soon.

Other researchers are developing methods to inhibit glioma tumors from

spreading throughout the brain. In order to expand, glioma cells break free

by altering molecules that hold them in place (called extracellular matrix

molecules), like the glioma-enriched protein BEHAB. To travel through the

brain’s narrow spaces, glioma cells also undergo physical changes in size

and shape, a process that involves ion channels like glioma chloride

channels.

Targeting these molecules with a toxin could not only wipe out the cancer

cells and spare the healthy cells, but also could impede the cancer cells’

expansion. Scientists discovered that chlorotoxin, a molecule from the venom

of the giant yellow Israeli scorpion, specifically blocks glioma chloride

channels, preventing glioma tumor expansion. And linking a poison to

chlorotoxin kills glioma tumor cells without affecting healthy cells,

according to tests on animal models and in cells in a petri dish. A

synthetic version of chlorotoxin (TM-601) is currently in clinical trials in

people.

On another front, researchers are examining how blood vessels link up with

glioma tumors to nourish them. Many scientists believe that disrupting the

union will starve the tumors to death. The protein, vascular endothelial

growth factor (VEGF), is one target under investigation (see illustration).

Researchers recently used a gene therapy technique to interfere with VEGF's

activity at specific binding areas. Glioma growth was inhibited by 90 to 95

percent in animal models. An early study of patients with other types of

cancer is evaluating a small molecule that also appears to block VEGF

activity. Neuroscientists believe the molecule may be a simple way to starve

glioma tumors and are testing it in animal models.

------------------------------

A. Researchers believe one mechanism that allows blood vessels to offer a

nourishing connection to the tumor involves VEGF. The protein, secreted by

hungry tumor cells, attaches to binding sites on the normal blood vessel.

The signaling attracts the vessels to the tumor. B. Strategies that

interfere with the binding may cause the blood vessel cells to die. This

starves the tumor, kills its cells and shrinks it.

Illustration by Lydia Kibiuk, Copyright © 1998 Lydia Kibiuk

>

>

>

> Dear All

>

> I have a young lad of 22 coming to see me, diagnosed with a glioma in

> the brainstem discovered while having a brainscan for drug testing. The

> only treatment he has been offered is radiotherapy but he would rather

> avoid this. He is otherwise healthy, but did mention a prior blow to the

> head in this area, I am not sure how long ago. He has been advised that

> he may have had the glioma for some time. He notices head pains on

> first getting up in the morning and also has slight visual disturbances.

>

> I was thinking first of anti-inflammatories and notice Boswellia has

> previously been indicated on this list for glioma. I was considering

> Turmeric and also Centella due to the past trauma. Would circulatory

> herbs such as ginkgo be indicated? He reports that his symptoms improve

> when he goes running. He is very keen to help himself and I understand

> has changed his diet dramatically under the guidance of a nutritionist.

>

> Are herbs likely to make an impact on this condition? I feel somewhat

> out of my depth with this one and would appreciate any advice.

>

> Many thanks

> Verity

>

>

>

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