INTRAcrinology - for a healthier menoapuse and thyroid health and andropause ETC

[Guest guest]

i posted this info on another site and wanted to here as well

this is info that none of the 'practicing' doctors, not even the good ones, are

talking about. this science of INTRAcrinology has been known for 20+ years and

growing :0

yet it is clear that not even the Good doctors understand Consciously why urine

testing of Sex hormone's metabolic " end products " is crucial!!

so here is the long version

google for more :/

******Re: HRT question

>

> the problem is that the DRs are ignoring many areas of science that has

existed for 20+ years - and they are relying on the wrong tests based on age,

time of life, and whether one is taking Hormones

> etc

>

> just like thyroid patients, all men and women should know what the field of

INTRAcrinology is

>

> in a nutshell:

> INTRAcrinology means that any and all of our brain cells and body cells can

and Should continue to make thyroid and Sex hormones --

> at all ages.

>

> INTRAcrine production of hormones by ALL brain and body cells means:

> we make them out of the " pro-hormones " that are released by the respective

Endocrine glands

>

> EG)

> thyroid gland makes t4 (mostly) and then our Gland

> releases it out to blood stream where any and all brain and body cells can and

should 'grab' it and either use that t4 OR make their own t3 or t2 or t1 (or

even rt3) and use it INTeranlly

>

>

> *******************************************************************

>

> Good news

> Intracrine production of Sex hormones should continue ALL our lives!:

>

> this will blow you away cuz NO doctors are explaning this write /or

" practicing " this *Consciously*

>

>

> the adrenal glansd should take the choleesterol our liver should be making and

then thru complex " biochemical metabolic-enzyme pathways,

> our adrenal glands Should be making pregnenalone and

> DHEA and DHEA-S*(Very important as Sulfated /storage form) .

>

> (NOTE: Thyroid hormones also rely on SULFONATION enzyme/biochemistry!)

> Sulfonation is a KEY pathway that MUST be working in order for body to make

AND USE both Sex hormones and Thryodi hormones!

>

>

> anyway:

> the adrenal gladns should release the DHEAs and Pregnanliens) out to our

blood stream in good numbers (DO BLOOD TEST for those)

> to share with all of our brain and body cells

> which then EACH of our Cells via Intracrinology

> then should make their own Estrogesns/3 Testostereins (2) and progesterine

LOCALLY, out of the DHEA-S etc

>

> Sex hornmones via INTRAcrinology

> should be Made Locally

> Used Localy (insdie the cells0

> and Metabolized (Converetd to Metabolic End PRoduct) LOCALLY inside the cell

>

> which NEVEr shows up in Blood or saliva tests!!

>

> Only the " Metabolic End products " get released back into blood stream and

lyphn to be taken to kidnesy

> and peed out via urine

>

> Which is where URINE lab tests for Estrogne END Products (like the 2:16 test)

are coming into play!

>

>

> -Carol

>

> GOOD NEWS about Menopause and andropause

>

> btw Menopause andropause helps keep the Sex organs healthier (EG Prostate

breasts, Uterus and goands) because they do not need to be " Flooded " in E and T

for 80 years

>

> the localized /as needed/ production

> AKA INTRAcrine production of sex hormones

> goes on from birth to death

>

> More Good News

>

> it is a fact that Humans (and 2 other " higher primates " are the ONLY mammals

who can and should continue to make High levels of DHEA/ DHEA-S

> which measn Even Women were programmed to living LONG AND HEALTHY long after

our " menopause occurs

>

> IOW:

> INTracrine production of Eestrogens and Testosterone etc

> should continue long past our Menopause

> thanks to our Adrenal glands making " high " levels of DHEA/S and our brain/body

cells INTRAcrine productino of e and t and p

>

> PPS

> BTW i am not saying that no women can take BRHT!

> lord knows that being left hypot and " AFd " for years

> means we can have unhealhty " MEtabolic Enzyme pathways or unoptiumally low

levels of DHEA-S

>

> But i just wanted to warn you that SALIVA TESTS and BLood tests for E and T

> are NOT useful for telling you your **INTRAcrine production** of Estrogens and

Testosterine

>

>

> (I think the getting bigger boobs at menopause is a SULFONATION/ INTRAcrine

problem.

> excaberated by the Cortisol Pathway stealing " Co factors " from our sex steriod

and metabolism/conversion pathways....

>

here is an in depth article on INTRAcrine productino of Ts and Estrogens.

(but as you read it , focus on the known proven science they describe VS their

current topic of whether to supplement DHEA or not..

remember these conventiaonl scientists do not think about " Adrenal

Fatigue " ...

so they actually believe that Supplementing DHEA would be useful to study and

focus on

, VS

figuring out how to help patietns restore our " metabolic Enzyme " pathways via

nutrients and 'stress-managemen Re-wiring ' via the CNS nervsou system

and gut health and thyroid health and gluten-free

etc etc

http://humupd.oxfordjournals.org/content/13/3/239.full

this is 1 HTML web page from the OXFORD JOURNALS website.

Read the Section Titled:

PHYSIOLOGY

including this bit:

"

It has been estimated that, in women, 75% of estrogens are produced by

**intracrine activity in the peripheral tissues _before menopause_

and

close to 100% after (Labrie et al., 1988; Labrie, 1991).

In addition, it has been estimated that women produce approximately 71% of the

total androgens synthesized in men, mostly DHT and testosterone produced from

DHEA and DHEAS in the peripheral tissues (Labrie, 2003).

"

-Carol

[Guest guest]

linked here is a (partial ) list from the ENdocrine Reviews html website

of all the body parts that can and should make our Estrogens and Testosterone

(including DHT even in women) for all of our lives including _after menopause_!

these estrogens and testosteornes will NOt show up in blood or saliva tests -

becuz they are created only inside the cells of all the body and brain parts

listed in the linked table.

http://edrv.endojournals.org/content/24/2/152/T2.expansion.html

this lists about 25 of the body and brain parts that can and should continue to

make Estrogens (and other sex hromones) at all periods of life.

note: the items listed at the top of the " table "

are the Names of the metabolic/endocrine Enzymes that actually convert 1 hormone

into the next up/down the line...

(Example:

dhea-s makes testosterone which can be converted to make Estrogens .. or

converetd into DHT .

the enzyme called 5α-Reductase

converts testoterone into DHT (which is just as important in women's

vulvovaginal health as estrogen BTW) including after menopause.

-Carol

>

> i posted this info on another site and wanted to here as well

>

> this is info that none of the 'practicing' doctors, not even the good ones,

are talking about. this science of INTRAcrinology has been known for 20+ years

and growing :0

>

> yet it is clear that not even the Good doctors understand Consciously why

urine testing of Sex hormone's metabolic " end products " is crucial!!

>

> so here is the long version

> google for more :/

>

>

> ******Re: HRT question

>

>

>

> >

> > the problem is that the DRs are ignoring many areas of science that has

> existed for 20+ years - and they are relying on the wrong tests based on age,

> time of life, and whether one is taking Hormones

> > etc

> >

> > just like thyroid patients, all men and women should know what the field of

> INTRAcrinology is

> >

> > in a nutshell:

> > INTRAcrinology means that any and all of our brain cells and body cells can

> and Should continue to make thyroid and Sex hormones --

> > at all ages.

> >

> > INTRAcrine production of hormones by ALL brain and body cells means:

> > we make them out of the " pro-hormones " that are released by the respective

> Endocrine glands

> >

> > EG)

> > thyroid gland makes t4 (mostly) and then our Gland

> > releases it out to blood stream where any and all brain and body cells can

and

> should 'grab' it and either use that t4 OR make their own t3 or t2 or t1 (or

> even rt3) and use it INTeranlly

> >

> >

> > *******************************************************************

> >

> > Good news

> > Intracrine production of Sex hormones should continue ALL our lives!:

> >

> > this will blow you away cuz NO doctors are explaning this write /or

> " practicing " this *Consciously*

> >

> >

> > the adrenal glansd should take the choleesterol our liver should be making

and

> then thru complex " biochemical metabolic-enzyme pathways,

> > our adrenal glands Should be making pregnenalone and

> > DHEA and DHEA-S*(Very important as Sulfated /storage form) .

> >

> > (NOTE: Thyroid hormones also rely on SULFONATION enzyme/biochemistry!)

> > Sulfonation is a KEY pathway that MUST be working in order for body to make

> AND USE both Sex hormones and Thryodi hormones!

> >

> >

> > anyway:

> > the adrenal gladns should release the DHEAs and Pregnanliens) out to our

> blood stream in good numbers (DO BLOOD TEST for those)

> > to share with all of our brain and body cells

> > which then EACH of our Cells via Intracrinology

> > then should make their own Estrogesns/3 Testostereins (2) and progesterine

> LOCALLY, out of the DHEA-S etc

> >

> > Sex hornmones via INTRAcrinology

> > should be Made Locally

> > Used Localy (insdie the cells0

> > and Metabolized (Converetd to Metabolic End PRoduct) LOCALLY inside the cell

> >

> > which NEVEr shows up in Blood or saliva tests!!

> >

> > Only the " Metabolic End products " get released back into blood stream and

> lyphn to be taken to kidnesy

> > and peed out via urine

> >

> > Which is where URINE lab tests for Estrogne END Products (like the 2:16

test)

> are coming into play!

> >

> >

> > -Carol

> >

> > GOOD NEWS about Menopause and andropause

> >

> > btw Menopause andropause helps keep the Sex organs healthier (EG Prostate

> breasts, Uterus and goands) because they do not need to be " Flooded " in E and

T

> for 80 years

> >

> > the localized /as needed/ production

> > AKA INTRAcrine production of sex hormones

> > goes on from birth to death

> >

> > More Good News

> >

> > it is a fact that Humans (and 2 other " higher primates " are the ONLY mammals

> who can and should continue to make High levels of DHEA/ DHEA-S

> > which measn Even Women were programmed to living LONG AND HEALTHY long after

> our " menopause occurs

> >

> > IOW:

> > INTracrine production of Eestrogens and Testosterone etc

> > should continue long past our Menopause

> > thanks to our Adrenal glands making " high " levels of DHEA/S and our

brain/body

> cells INTRAcrine productino of e and t and p

> >

> > PPS

> > BTW i am not saying that no women can take BRHT!

> > lord knows that being left hypot and " AFd " for years

> > means we can have unhealhty " MEtabolic Enzyme pathways or unoptiumally low

> levels of DHEA-S

> >

> > But i just wanted to warn you that SALIVA TESTS and BLood tests for E and T

> > are NOT useful for telling you your **INTRAcrine production** of Estrogens

and

> Testosterine

> >

> >

> > (I think the getting bigger boobs at menopause is a SULFONATION/

INTRAcrine

> problem.

> > excaberated by the Cortisol Pathway stealing " Co factors " from our sex

steriod

> and metabolism/conversion pathways....

> >

>

>

> here is an in depth article on INTRAcrine productino of Ts and Estrogens.

> (but as you read it , focus on the known proven science they describe VS their

> current topic of whether to supplement DHEA or not..

>

> remember these conventiaonl scientists do not think about " Adrenal

> Fatigue " ...

> so they actually believe that Supplementing DHEA would be useful to study and

> focus on

> , VS

> figuring out how to help patietns restore our " metabolic Enzyme " pathways via

> nutrients and 'stress-managemen Re-wiring ' via the CNS nervsou system

> and gut health and thyroid health and gluten-free

> etc etc

>

> http://humupd.oxfordjournals.org/content/13/3/239.full

> this is 1 HTML web page from the OXFORD JOURNALS website.

>

> Read the Section Titled:

> PHYSIOLOGY

>

> including this bit:

> "

> It has been estimated that, in women, 75% of estrogens are produced by

> **intracrine activity in the peripheral tissues _before menopause_

> and

> close to 100% after (Labrie et al., 1988; Labrie, 1991).

>

> In addition, it has been estimated that women produce approximately 71% of the

> total androgens synthesized in men, mostly DHT and testosterone produced from

> DHEA and DHEAS in the peripheral tissues (Labrie, 2003).

> "

>

> -Carol

>

[Guest guest]

hi

this intracrine production /of sex hormones and how to TEST with Labs etc is

hard for me to explain but i found 2 links that will help clarify :

1) what intracrinology is

and

2) why it is the KEY to *human female menopause meaning a LOONG and healthy life

for decades AFTER women pass Menopause

btw this science has been around for well over 20 years now

and i am appalled at this point, how stupid doctors are with all their talk that

" in the past " women never lived much past menopause AND that women do not have

'high' levels of sex hormoens in their body After menopause.

wrong wrong wrong.

frightening how wrong they have been all this time. is this misogyny ?

~*

http://www.ncbi.nlm.nih.gov/pubmed/20541662

DHEA, important source of sex steroids in men and even more in women.

Labrie F.

"

A major achievement from 500 million years of evolution is the establishment of

a high secretion rate of dehydroepiandrosterone (DHEA) by the human adrenal

glands coupled with the indroduction of menopause which stops secretion of

estrogens by the ovary.

"

In fact, from the time of menopause, DHEA becomes the exclusive and

tissue-specific source of sex steroids for all tissues except the uterus.

Intracrinology, a term coined in 1988, describes the local formation, action and

inactivation of sex steroids from the inactive sex steroid precursor DHEA

....

"

In addition, there is a _large variability_ in the circulating levels of DHEA

with some post-menopausal women having barely detectable serum concentrations of

the steroid while others have *normal values

"

{hello 'Adrenal Fatigue " ! :/

the Cortisol steal (and nutritional-resources-steal) at work there.

HUman adrenal gladns aer genetically programmed to keep making HIGH levels of

DHEAs

which then any and all of our brain and body cells can use Internally -to make

their own Sex hormones- when THEY want to

ingenious.

regards

-Carol

> >

> > i posted this info on another site and wanted to here as well

> >

> > this is info that none of the 'practicing' doctors, not even the good ones,

are talking about. this science of INTRAcrinology has been known for 20+ years

and growing :0

> >

> > yet it is clear that not even the Good doctors understand Consciously why

urine testing of Sex hormone's metabolic " end products " is crucial!!

> >

> > so here is the long version

> > google for more :/

> >

> >

> > ******Re: HRT question

> >

> >

> >

> > >

> > > the problem is that the DRs are ignoring many areas of science that has

> > existed for 20+ years - and they are relying on the wrong tests based on

age,

> > time of life, and whether one is taking Hormones

> > > etc

> > >

> > > just like thyroid patients, all men and women should know what the field

of

> > INTRAcrinology is

> > >

> > > in a nutshell:

> > > INTRAcrinology means that any and all of our brain cells and body cells

can

> > and Should continue to make thyroid and Sex hormones --

> > > at all ages.

> > >

> > > INTRAcrine production of hormones by ALL brain and body cells means:

> > > we make them out of the " pro-hormones " that are released by the respective

> > Endocrine glands

> > >

> > > EG)

> > > thyroid gland makes t4 (mostly) and then our Gland

> > > releases it out to blood stream where any and all brain and body cells can

and

> > should 'grab' it and either use that t4 OR make their own t3 or t2 or t1 (or

> > even rt3) and use it INTeranlly

> > >

> > >

> > > *******************************************************************

> > >

> > > Good news

> > > Intracrine production of Sex hormones should continue ALL our lives!:

> > >

> > > this will blow you away cuz NO doctors are explaning this write /or

> > " practicing " this *Consciously*

> > >

> > >

> > > the adrenal glansd should take the choleesterol our liver should be making

and

> > then thru complex " biochemical metabolic-enzyme pathways,

> > > our adrenal glands Should be making pregnenalone and

> > > DHEA and DHEA-S*(Very important as Sulfated /storage form) .

> > >

> > > (NOTE: Thyroid hormones also rely on SULFONATION enzyme/biochemistry!)

> > > Sulfonation is a KEY pathway that MUST be working in order for body to

make

> > AND USE both Sex hormones and Thryodi hormones!

> > >

> > >

> > > anyway:

> > > the adrenal gladns should release the DHEAs and Pregnanliens) out to our

> > blood stream in good numbers (DO BLOOD TEST for those)

> > > to share with all of our brain and body cells

> > > which then EACH of our Cells via Intracrinology

> > > then should make their own Estrogesns/3 Testostereins (2) and progesterine

> > LOCALLY, out of the DHEA-S etc

> > >

> > > Sex hornmones via INTRAcrinology

> > > should be Made Locally

> > > Used Localy (insdie the cells0

> > > and Metabolized (Converetd to Metabolic End PRoduct) LOCALLY inside the

cell

> > >

> > > which NEVEr shows up in Blood or saliva tests!!

> > >

> > > Only the " Metabolic End products " get released back into blood stream and

> > lyphn to be taken to kidnesy

> > > and peed out via urine

> > >

> > > Which is where URINE lab tests for Estrogne END Products (like the 2:16

test)

> > are coming into play!

> > >

> > >

> > > -Carol

> > >

> > > GOOD NEWS about Menopause and andropause

> > >

> > > btw Menopause andropause helps keep the Sex organs healthier (EG Prostate

> > breasts, Uterus and goands) because they do not need to be " Flooded " in E

and T

> > for 80 years

> > >

> > > the localized /as needed/ production

> > > AKA INTRAcrine production of sex hormones

> > > goes on from birth to death

> > >

> > > More Good News

> > >

> > > it is a fact that Humans (and 2 other " higher primates " are the ONLY

mammals

> > who can and should continue to make High levels of DHEA/ DHEA-S

> > > which measn Even Women were programmed to living LONG AND HEALTHY long

after

> > our " menopause occurs

> > >

> > > IOW:

> > > INTracrine production of Eestrogens and Testosterone etc

> > > should continue long past our Menopause

> > > thanks to our Adrenal glands making " high " levels of DHEA/S and our

brain/body

> > cells INTRAcrine productino of e and t and p

> > >

> > > PPS

> > > BTW i am not saying that no women can take BRHT!

> > > lord knows that being left hypot and " AFd " for years

> > > means we can have unhealhty " MEtabolic Enzyme pathways or unoptiumally low

> > levels of DHEA-S

> > >

> > > But i just wanted to warn you that SALIVA TESTS and BLood tests for E and

T

> > > are NOT useful for telling you your **INTRAcrine production** of Estrogens

and

> > Testosterine

> > >

> > >

> > > (I think the getting bigger boobs at menopause is a SULFONATION/

INTRAcrine

> > problem.

> > > excaberated by the Cortisol Pathway stealing " Co factors " from our sex

steriod

> > and metabolism/conversion pathways....

> > >

> >

> >

> > here is an in depth article on INTRAcrine productino of Ts and Estrogens.

> > (but as you read it , focus on the known proven science they describe VS

their

> > current topic of whether to supplement DHEA or not..

> >

> > remember these conventiaonl scientists do not think about " Adrenal

> > Fatigue " ...

> > so they actually believe that Supplementing DHEA would be useful to study

and

> > focus on

> > , VS

> > figuring out how to help patietns restore our " metabolic Enzyme " pathways

via

> > nutrients and 'stress-managemen Re-wiring ' via the CNS nervsou system

> > and gut health and thyroid health and gluten-free

> > etc etc

> >

> > http://humupd.oxfordjournals.org/content/13/3/239.full

> > this is 1 HTML web page from the OXFORD JOURNALS website.

> >

> > Read the Section Titled:

> > PHYSIOLOGY

> >

> > including this bit:

> > "

> > It has been estimated that, in women, 75% of estrogens are produced by

> > **intracrine activity in the peripheral tissues _before menopause_

> > and

> > close to 100% after (Labrie et al., 1988; Labrie, 1991).

> >

> > In addition, it has been estimated that women produce approximately 71% of

the

> > total androgens synthesized in men, mostly DHT and testosterone produced

from

> > DHEA and DHEAS in the peripheral tissues (Labrie, 2003).

> > "

> >

> > -Carol

> >

>