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Reported April 25, 2005

Diabetes Drug Helps Multiple Sclerosis

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CHICAGO (Ivanhoe Broadcast News) -- Nearly 350,000 Americans suffer from

multiple sclerosis, a disease that strikes women twice as often as men. Some

treatments are available for this crippling disease, but all require injections.

Now a common diabetes drug could be the latest breakthrough for MS.

Eight-month-old na has just arrived from Guatemala. Her adoptive

mother, Marjorie Fujara, is ready for the challenges of motherhood, but at age

41, Marjorie faces a more serious challenge.

Eight years ago, doctors diagnosed Marjorie with multiple sclerosis. " It

was devastating, " she says. " My mother was diagnosed with MS and had a very

aggressive course with hers. "

Marjorie's mother died from MS after 12 years. Today, she is in a trial to

test a new treatment -- a drug that is used for diabetes.

Neuroscientist Feinstein, Ph.D., of University of Illinois at

Chicago, says, " The relationship between type 2 diabetes and multiple sclerosis

-- there probably isn't any really strong correlation, and it's just a

serendipitous discovery that we came across. "

The drug pioglitazone is known to type 2 diabetes patients as Actos. Lab

studies with the drug for MS look encouraging. If the study results continue to

show promise, pioglitazone could become the first treatment for MS taken in pill

form, eliminating the need for injections.

So far, things are looking good for Marjorie. Her symptoms are not flaring

up as often, and she has no side effects. " Just knowing there are people --

bright, dedicated researchers out there -- really gives me a lot of hope, " she

says.

This new drug trial for ms is nearly half over. Researchers at the

University of Illinois expect to release the results in the spring of 2006.

Researchers around the world are also testing this same drug for the treatment

of Alzheimer's and Parkinson's disease.

This article was reported by Ivanhoe.com, who offers Medical Alerts by

e-mail every day of the week. To subscribe, go to:

http://www.ivanhoe.com/newsalert/.

If you would like more information, please contact:

Sharon

Office of Public Affairs

University of Illinois at Chicago

601 South MC 288

Chicago, IL 60607-7113

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