Malathion Medical Research

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http://www.chem-tox.com/malathion/research/index.htm

Malathion's Real Name is

Dimethoxy Phosphino Thioyl Thio Butanedioic Acid Diethyl Ester Malathion

Molecule

C10 H19 O6 P S2

by Wayne Sinclair, M.D.

Allergy, Asthma & Immunology (Immunology Board Certified)

W. Pressinger, M.Ed., Tampa, Florida

email: research@...

The malathion medical research below was located from the University of

Florida and University of South Florida Medical Libraries. As can be seen

here, in contrast to what the public is being told by the Agriculture

Industry and New York politicians, scientists are stating that malathion

(even at low levels) is in fact, a harmful chemical.

Health Effects Research Summaries

Malathion Not as Safe as Believed - 5 Die - 2,800 Poisoned

SOURCE: Archives in Toxicology, 42:95-106, 1979

The following information is from the report from the Bureau of Tropical

Diseases, Center for Disease Control, Atlanta, Georgia entitled " The

Toxicological Properties of Impurities in Malathion. " Below is a direct

quote from the introductory abstract to the article:

" During a malaria eradication program in Pakistan in 1976, out of 7,500

spray men, 2,800 became poisoned and 5 died. The major determinant of the

poisoning has been identified as isomalathion present as an impurity in the

malathion. It seems almost certain that the isomalathion was produced during

storage of the formulated malathion.

The quantitative correlation found between isomalathion content and toxicity

of many field samples of malathion has been confirmed by an examination of

mixtures of pure compounds. Addition of known amounts of isomalathion to

technical malathion indicates that other active substances are present.

These impurities have been identified (trimethyl phosphorothioates) and have

been shown to behave like isomalathion in potentiating the toxicity of

malathion. Some preliminary work on their toxicological properties is

reported. "

Drs. W.N. Aldridge, J.W. Miles, D.L. Mount and R.D. Verschoyle

Toxicology Unit, Medical Research Council Laboratories

Pesticides Branch, Vector Biology and Control Division

Center for Disease Control, Atlanta GA

See links at website

Intestinal Disorders in Children Born After California Spraying

SOURCE: Epidemiology, 3(1):32-39, January, 1992

This is the first study to show evidence of harm to human health after

aerial sprayings of malathion over human populations. Investigators surveyed

933 pregnancies identified through hospitals in the San Francisco Bay Area,

in relation to exposure to the pesticide malathion, applied aerially to

control the Mediterranean fruit fly. The good news is that after adjustment

for confounding factors, there was no association found between malathion

exposure and spontaneous abortion, intrauterine growth retardation,

stillbirth, or most categories of congenital abnormalities.

However, it was found that children who had been exposed to malathion during

the second trimester of pregnancy were showing over two and one-half times

more gastrointestinal disorders (affecting the stomach and small intestines)

in comparison to children not exposed to malathion during pregnancy.

Chem-Tox Comments: When the Florida Dept of Agriculture says there is no

research showing harm to public health after malathion spraying - this is a

complete and total lie as here is the research in black and white. This one

study certainly raises enough of a red flag to immediately suspend all

aerial applications of malathion and supports the animal research showing

genetic defects and abnormal growth of cells after exposure to malathion.

Unfortunately, this study did not investigate for increases in subtle

neurological disorders such as language delays, attention deficits, learning

disabilities, hyperactivity or conduct disorders, which the research has

shown occurs with other chemicals at exposure levels far under that which

causes physical health effects. To look at our website which summarizes the

research showing modern chemicals at very low doses can cause subtle child

behavior and learning disorders, please visit

http://www.chem-tox.com/pregnancy/learning_disabilities.htm

Department of Preventive Medicine

University of Southern California, Los Angeles

Child Leukemia & Aplastic Anemia after Malathion Exposure

SOURCE: The Lancet, pg.300, August 8, 1981

Seven children with bone marrow disorders have been observed over the past 8

years by physicians at Air Force Base Medical Center in California.

The physicians believe the blood disorders, in all cases, were caused by

organophosphate pesticides.. All blood disorders occurred shortly after

exposure to the pesticides DDVP/propoxur and malathion. The duration of

inhaling insecticides ranged from 2 minutes in a patient enveloped in a

thick insecticide fog in a small shed to 2 days in other patients whose

homes were fumigated by their parents. Six patients had aplastic anemia and

one had acute lymphoblastic leukemia. The physicians also cited research

showing leukemia in farmers has significantly increased during the period of

1964 to 1976 (Mayo Clinic Proc, 53:714-18, 1978). Apple growers exposed to

organophosphates had a higher incidence of leukopenia (very low white blood

count) than a control population (Canadian Medical Association Journal,

92:597-602, 1965).

Drs. Jerry D. Reeves, A. Driggers, A Kiley

Department of Pediatrics, Grant Medical Center

Air Force Base, California