Cracked Skin Could Be Path to Asthma

[Guest guest]

From the New York Times:

February 8, 2007

Cracked Skin Could Be Path to Asthma

By LAUREL NAVERSEN GERAGHTY

RESEARCHERS have long noted that many _asthma_

(http://topics.nytimes.com/top/news/health/diseasesconditionsandhealthtopics/ast\

hma/index.html?inline=nyt-cl

assifier) sufferers also have atopic dermatitis & shy; often called eczema

& shy; a chronic disease of the skin that can leave it red, raw, scaly, tender,

oozy and excruciatingly itchy. But scientists are looking at whether such

ravaging of the skin creates the conditions that can trigger asthma.

Last spring in the journal Nature Genetics, British scientists reported that

people who suffer from both eczema and asthma carry the same gene mutation

and concluded that eczema may actually lead to asthma in some cases.

Until now, it had largely been assumed that dander, dust mites, pollen and

other allergens that can cause asthma enter the body through the respiratory

system. But the researchers said they now believe that they can also enter the

body through tiny breaks in the skin’s surface & shy; something that occurs

in patients with eczema.

“Allergens from our environment can actually enter the skin through these

cracks,†said Dr. J. Hudson, an immunologist and the president and

scientific director of the Ontario Institute for _Cancer_

(http://topics.nytimes.com/top/news/health/diseasesconditionsandhealthtopics/can\

cer/index.html?inline=ny

t-classifier) Research, who was not affiliated with the study but wrote a

commentary on it in Nature Genetics, “and the immune cells under the skin

cells appear to be reacting and forming an allergic reaction†to them.

That allergic reaction “can prime the immune system so that subsequent

inhalation of the same allergens leads to a reaction in the lungs and

contributes

to the development of asthma,†Dr. Schaffer, an assistant professor of

dermatology at _New York University_

(http://topics.nytimes.com/top/reference/timestopics/organizations/n/new_york_un\

iversity/index.html?inline=nyt-org)

School of Medicine, wrote in an e-mail message.

The researchers also found that two gene mutations, known to diminish the

skin’s ability to form its protective outer barrier, were present in people

with both asthma and eczema, confirming that the two can be genetically linked.

But individuals who had asthma but no eczema did not have the mutations.

The lack of a direct link between asthma and the mutations & shy; when eczema

was not present & shy; suggests that sensitization may arise after eczema

sets in, as a result of a weakened skin barrier, Dr. Hudson concluded.

Doctors said their strongest hope is that the discovery could lead to new

ways to prevent asthma in people who are genetically susceptible. The measures

could be as simple as using moisturizer and gentle cleansers on babies and

children to improve the health of their skin, said Dr. Jon M. Hanifin, a

professor of dermatology at Oregon Health and Science University and a

consultant

to drug companies.

Dr. Hudson said: “When we find here a direct link between the skin barrier

and asthma, it makes you think, ‘Could we be doing something different? Could

we be affecting the skin of our kids?’ But if there were ways we could

improve the maintenance of this epithelial barrier, we would prevent subsequent

asthma.â€

LAUREL NAVERSEN GERAGHTY

[Guest guest]

poor baby sleeps on a new flame resistant mattress, and on new poly blend sheets

washed in scented detergents with scented bounce and maybe some bleach thrown in

there for good measure. the furniture in their carpeted rooms is new and the

walls are freshly painted. and mom might just have a plug in in there to cover

up smelly diaper odor. he is bathed in scented johnson and johnson products and

regularly lotioned and powdered with scented products. he is nursed hopefully

so as to get the colustrum but often not for long as mom has to go back to work.

and develops food allergies to formulas.

don't you think they would get a clue as to how baby gets asthma and eczema???

snk1955@... wrote:

From the New York Times:

February 8, 2007

Cracked Skin Could Be Path to Asthma

By LAUREL NAVERSEN GERAGHTY

RESEARCHERS have long noted that many _asthma_

(http://topics.nytimes.com/top/news/health/diseasesconditionsandhealthtopics/ast\

hma/index.html?inline=nyt-cl

assifier) sufferers also have atopic dermatitis & shy; often called eczema

& shy; a chronic disease of the skin that can leave it red, raw, scaly, tender,

oozy and excruciatingly itchy. But scientists are looking at whether such

ravaging of the skin creates the conditions that can trigger asthma.

Last spring in the journal Nature Genetics, British scientists reported that

people who suffer from both eczema and asthma carry the same gene mutation

and concluded that eczema may actually lead to asthma in some cases.

Until now, it had largely been assumed that dander, dust mites, pollen and

other allergens that can cause asthma enter the body through the respiratory

system. But the researchers said they now believe that they can also enter the

body through tiny breaks in the skin’s surface & shy; something that occurs

in patients with eczema.

“Allergens from our environment can actually enter the skin through these

cracks,†said Dr. J. Hudson, an immunologist and the president and

scientific director of the Ontario Institute for _Cancer_

(http://topics.nytimes.com/top/news/health/diseasesconditionsandhealthtopics/can\

cer/index.html?inline=ny

t-classifier) Research, who was not affiliated with the study but wrote a

commentary on it in Nature Genetics, “and the immune cells under the skin

cells appear to be reacting and forming an allergic reaction†to them.

That allergic reaction “can prime the immune system so that subsequent

inhalation of the same allergens leads to a reaction in the lungs and

contributes

to the development of asthma,†Dr. Schaffer, an assistant professor of

dermatology at _New York University_

(http://topics.nytimes.com/top/reference/timestopics/organizations/n/new_york_un\

iversity/index.html?inline=nyt-org)

School of Medicine, wrote in an e-mail message.

The researchers also found that two gene mutations, known to diminish the

skin’s ability to form its protective outer barrier, were present in people

with both asthma and eczema, confirming that the two can be genetically

linked.

But individuals who had asthma but no eczema did not have the mutations.

The lack of a direct link between asthma and the mutations & shy; when eczema

was not present & shy; suggests that sensitization may arise after eczema

sets in, as a result of a weakened skin barrier, Dr. Hudson concluded.

Doctors said their strongest hope is that the discovery could lead to new

ways to prevent asthma in people who are genetically susceptible. The measures

could be as simple as using moisturizer and gentle cleansers on babies and

children to improve the health of their skin, said Dr. Jon M. Hanifin, a

professor of dermatology at Oregon Health and Science University and a

consultant

to drug companies.

Dr. Hudson said: “When we find here a direct link between the skin barrier

and asthma, it makes you think, ‘Could we be doing something different?

Could

we be affecting the skin of our kids?’ But if there were ways we could

improve the maintenance of this epithelial barrier, we would prevent

subsequent

asthma.â€

LAUREL NAVERSEN GERAGHTY

[Guest guest]

I wonder if similar mechanisms might be partially responsible for toxins

creating such a reaction in people. When you live in a toxin-filled

environment, some of it is going to get in through cracks in your skin,

especially if you have diseases like reflux or ear infections or anything

where you skin gets broken. Really, just living in a toxin environment over

time would seem to make such 'sensitization' almost inevitable, as we don't

expect our environment to be toxic and so don't treat it as such. (by

wearing PPE at all times, like it would seem they expect us to do.. to

simulate the sterile laboratory conditions that are used to 'legally'

declare our having to live in mycotoxins to be healthy and not dangerous)

[Guest guest]

Jane - I have often run through that scenario in my head. Add to it: sucking on

plastic/vinyl pacifiers and nipples - and formula in plastic bottles, some

microwaved in the plastic. What a mess. I recently shopped for a baby shower

gift and it was tough to find something that wasn't derived from synthetics or

plastics (often one and the same). Even the 100% cotton products are treated

with flame retardents, etc.

Can anyone answer this? - As for skin as a barrier - I thought skin was more

like a membrane that breathes and absorbs from the environment. Which is why

transdermal medication works, and why tyvek protection garments are required in

mold remediation and hazardous materials cleanup. So, why are 'they' assuming

cracks are necessary for toxins to get through skin? The genetic link may be of

significance, but their logic doesn't work for me. I think the eczema and skin

cracking is another symptom/reaction of whatever is causing the asthma, and the

genetics are a susceptibility factor for that trigger. But, who am I? Not a

scientist...

[Guest guest]

Sue,

I know for a fact that (low molecular weight) trichothecenes go right

through the skin.

I went for years having people at work ask me why my face was so red until I

finally realized that I needed to bathe/shower at night

because the red skin came after the bath (along with the ringing ears)

On 2/13/07, Sue ston <thecanaries@...> wrote:

>

>

> Can anyone answer this? - As for skin as a barrier - I thought skin was

> more like a membrane that breathes and absorbs from the environment. Which

> is why transdermal medication works, and why tyvek protection garments are

> required in mold remediation and hazardous materials cleanup. So, why are

> 'they' assuming cracks are necessary for toxins to get through skin? The

> genetic link may be of significance, but their logic doesn't work for me. I

> think the eczema and skin cracking is another symptom/reaction of whatever

> is causing the asthma, and the genetics are a susceptibility factor for that

> trigger. But, who am I? Not a scientist...

>

>

[Guest guest]

Me to Jane, sence I have MCS and I cannot even hold babies with those

smelly products on theri skin and in theri hair because I get so

affected by theri smells I'm afraid I will drop them because my arms

become weak and shaky and my airways close up,it litterly chokes me,

so whats it doing to those tiny baby lungs.what a sad world we live

in,where companys are getting rich off the products they sale without

any reguard for human kind. a few years ago I watched a baby gag for

breath as it's mother took a diaper wipe out to clean his face and I

just wanted to scream at her not to use that smelly crap on her baby.

those smelly diaper wipes will drive me right out of a house.

>

> Jane - I have often run through that scenario in my head. Add to

it: sucking on plastic/vinyl pacifiers and nipples - and formula in

plastic bottles, some microwaved in the plastic. What a mess. I

recently shopped for a baby shower gift and it was tough to find

something that wasn't derived from synthetics or plastics (often one

and the same). Even the 100% cotton products are treated with flame

retardents, etc.

> Can anyone answer this? - As for skin as a barrier - I thought skin

was more like a membrane that breathes and absorbs from the

environment. Which is why transdermal medication works, and why tyvek

protection garments are required in mold remediation and hazardous

materials cleanup. So, why are 'they' assuming cracks are necessary

for toxins to get through skin? The genetic link may be of

significance, but their logic doesn't work for me. I think the eczema

and skin cracking is another symptom/reaction of whatever is causing

the asthma, and the genetics are a susceptibility factor for that

trigger. But, who am I? Not a scientist...

>

>

>

[Guest guest]

Most soft plastic products have all sorts of bad chemicals in them it tuns

out. Endocrine disruptor plasticizers and lead.

There must be some that are semi safe.. but I know a lot of toys were banned

a few years ago because they are soft plastic and were small enough to fit

in the mouth..

[Guest guest]

Anything with " low molecular weight " which I understand most

mycotoxins to be.. will go through skin not unlike water does..

Many OTHER toxins don't pass through skin, but MYCOtoxins do... They

can cause necrosis at the entry site if the concentration is high

enough, otherwise they can go right into the bloodstream and get

carried all over the body until they get removed by the liver and

kidneys, which can also suffer damage in the process. They can also

concentrate in the brain, testes, and elsewhere..

This is explained very clearly in Mold Warriors and many other papers..