Hypovitaminosis D in Type 2 Diabetics: Association with Microvascular Complications and Treatment with Insulin

[Guest guest]

Colleagues, the following is FYI and does not necessarily reflect my own

opinion. I have no further knowledge of the topic. If you do not wish to

receive these posts, set your email filter to filter out any messages

coming from @nutritionucanlivewith.com and the program will remove

anything coming from me.

---------------------------------------------------------

Hypovitaminosis D in Type 2 Diabetics: Association with Microvascular

Complications and Treatment with Insulin

http://www.vitasearch.com/CP/weeklyupdates/

Reference: " Hypovitaminosis D in type 2 diabetes mellitus: Association

with microvascular complications and type of treatment, " Suzuki A,

Kotake M, et al, Endocr J, 2006; 53(4): 503-10. (Address: Department of

Internal Medicine, Fujita Health University, Toyoake, Japan).

Summary: In an observational study involving 581 type 2 diabetics and

51 healthy controls, serum concentrations of 25-OHD were found to be

associated with HbA1c, age, serum albumin, presence of microvascular

complications, and treatment with insulin. 70.6% of subjects were found

to have hypovitaminosis D (<20 ng/ml), with mean concentrations of

25-OHD being 17.0 ng/ml among the diabetics and 17.5 ng/ml among the

controls. Lower levels of 25-OHD were found among subjects with apparent

microvascular complications and subjects treated with insulin (15.4

ng/ml), compared to subjects treated with oral hypoglycemic agents (17.3

ng/ml), and subjects treated with diet alone (20.8 ng/ml). Diabetic

subjects treated with insulin with hypovitaminosis D were found to have

the highest incidence of osteoporotic fracture and/or back deformity.

Thus, the authors of this study conclude, " …these results suggest that

microvascular complications and insulin treatment in type 2 diabetes

patients are as sociated with the co-existence of hypovitaminosis D, and

that hypovitaminosis D in insulin-treated patients is possibly related

to the risk of osteoporotic fracture. "

--

ne Holden, MS, RD < fivestar@... >

" Ask the Parkinson Dietitian " http://www.parkinson.org/

" Eat well, stay well with Parkinson's disease "

" Parkinson's disease: Guidelines for Medical Nutrition Therapy "

http://www.nutritionucanlivewith.com/