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Urso/Actigall

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Sorry I can't help much in this discussion. Only Urso is available in

Canada. The same company makes it for both the US and Canada as of two

years ago. We had a bit of problem when this company, Axcan Pharma, took

over the manufacturing of Urso from another firm. We thought we might

end up with a shortage. In view of that, I purchased some extra and then

gave to another liver disease sufferer when I had my tx.

As mentioned, it was first approved for gall stone disolving. It's use

for cholestatic liver disease such as PSC, has never been shown to be of

benefit except in lowering LFTs levels. However, it has been used for

many years in this way. And some of us feel it has helped reduced the

number of episodes and perhaps the severity of cholangitis.

I'm sure that, for most people, these two are virtually

indistiguishable. There are some people who may not be able to tolerate

one but can take the other because of GI upset. Perhaps because of

quicker disolution of the product. This could be altered by taking with

food, in some cases.

Aubrey

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