Guest guest Posted May 22, 2003 Report Share Posted May 22, 2003 Barbara and all, We use pre-albumin quite a bit at the hospital I " prn " at for changing nutritional status. I would be interested in understanding the pros and cons to albumin, total protein, and pre-albumin measures. Anybody have that information? Ellen ===== Ellen Hansson, MEd, RD, LDN ISeeSpots Farm Sheep: Lambs, adults, wool www.iseespots.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 22, 2003 Report Share Posted May 22, 2003 You know, it's been 7 years since I worked clinical (trauma and neuro), but I do recall that although both albumin and pre-albumin would be low at admit, because of it's shorter half-life, we could see a better picture of how we were doing nutritionally with the pre-albumin. I do recall there were certain conditions that would keep it low, but it's been too long for me to remember what they are. I do remember there is good literature out there, though. Perhaps a Medline search could help. Margie -- Marjorie Geiser, RD, NSCA-CPT MEG Fitness Registered Dietitian ACE and NSCA certified personal trainer Southern California megfit@... Hansson wrote: Barbara and all, We use pre-albumin quite a bit at the hospital I "prn" at for changing nutritional status. I would be interested in understanding the pros and cons to albumin, total protein, and pre-albumin measures. Anybody have that information? Ellen ===== Ellen Hansson, MEd, RD, LDN ISeeSpots Farm Sheep: Lambs, adults, wool www.iseespots.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 23, 2003 Report Share Posted May 23, 2003 Here's some info that I have regarding serum albumin & prealbumin: ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Serum Albumin: Half-life ~ 18 days-limits its usefulness in detecting acute efficacy of nutrition support. Albumin is beneficial as a *prognostic* indicator of morbidity & mortality and as an indicator of malnutrition. Factors that affect the interpretation of serum albumin: Hydration status Degree of physiologic stress Extent of abnormal capillary permeability Protein depletion state-high output fistulas, open wounds, etc Hepatic dysfunction Pregnancy Use of blood products +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Regarding prealbumin: Half-life ~ 2-3 days) and is useful in *monitoring* nutritional interventions & refeeding. INCREASED levels of Prealbumin: Use of corticosteriods Acute ETOH intoxication Prednisone use Steroid use Progestational agents Falsely elevated levels in renal failure DECREASED levels of Prealbumin: Protein malnutrition Malignancy Cirrhosis Protein-losing enteropathy Zinc deficiency Hepatic disease Infection Severe stress Nephrotic syndrome Major metabolic stress Hyperthyroidism Transiently decr4ease in the presence of inflammation Innediate post-surgical period http:///www.aafp.org/20020415/1575.html " Although the prealbumin level is a sensitive indicator of inadequate nutrient intake, it should be used only as an integral part of an overall assessment program. " Dianne Kiyomoto ================================================================== > > > Barbara and all, > > > > We use pre-albumin quite a bit at the hospital I " prn " at for changing > > nutritional status. I would be interested in understanding the pros and > > cons to albumin, total protein, and pre-albumin measures. Anybody have > > that information? > > > > Ellen > > > > ===== > > Ellen Hansson, MEd, RD, LDN > > ISeeSpots Farm > > Sheep: Lambs, adults, wool > > www.iseespots.com > > > > Quote Link to comment Share on other sites More sharing options...
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