Re: Progesterone (and my rant)

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Lana writes:

if you're taking any oral estrogen you need to switch to transdermal to lower SHBG...if you're already taking transdermal you need to take less of it to lower SHBG...higher E, higher SHBG..although SHBG binds T a lot more than it binds E...

Lana,

Do you have a source for this info?

Dr. Uzzi Reiss writes about not taking oral or injectible in order to not raise SHBG. Other than that, I'd like to read more on the rest.

Thanks,

Lynne

[Guest guest]

it was actually me, who posted this, ..and it's coming right from Reiss...he says that if your SHBG is higher than 100 and your taking oral, switch to transdermal...wait 6-8 weeks till it decreases by 20%...if it's still above 100, then lower the dosage. He likes it around 90. Oral estrogen really raises SHBG..therefore all the girls on BCP have sky-high SHBG...mine, on a pill, was way above 150...lab couldn't even measure it that high...off the pill, i'll know tomorrow..but i expect it to be lower...if it's not under 100 in another 6-8 weeks, i'll cut my E some...lynnelalala@... wrote:

Lana writes:

if you're taking any oral estrogen you need to switch to transdermal to lower SHBG...if you're already taking transdermal you need to take less of it to lower SHBG...higher E, higher SHBG..although SHBG binds T a lot more than it binds E...

Lana,

Do you have a source for this info?

Dr. Uzzi Reiss writes about not taking oral or injectible in order to not raise SHBG. Other than that, I'd like to read more on the rest.

Thanks,

Lynne

>>>>>>OK....here's a twist.....my SHBG went up when I got on ORAL thyroid meds?????

Can it acts the same as oral E?????? Even when I had sky high transdermal E,

my SHBG didn't jump up til the addition of oral thyroid!!!! Just wonder if anyone has

seen this with their labs too???

[Guest guest]

..... I think it's SHBG, sex hormone binding globulin, that binds up

elevated E so it isn't detected in the blood. This is discovered by

having an SHBG blood test....

Eileen

>

> question next time I go back -- how do they account for such LOW

> readings of E in our bloodstream if we ARE using 18 mgs a day? 

[Guest guest]

Yes and then what? How do you lower the SHBG ? It's a no-win

situation!

> >

>

> > question next time I go back -- how do they account for such LOW

> > readings of E in our bloodstream if we ARE using 18 mgs a day? 

>

[Guest guest]

if you're taking any oral estrogen you need to switch to transdermal to lower SHBG...if you're already taking transdermal you need to take less of it to lower SHBG...higher E, higher SHBG..although SHBG binds T a lot more than it binds E... wrote: Yes and then what? How do you lower the SHBG ? It's a no-win situation! > >> > > question next time I go back -- how do they account for

such LOW> > readings of E in our bloodstream if we ARE using 18 mgs a day? >

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[Guest guest]

it was actually me, who posted this, ..and it's coming right from Reiss...he says that if your SHBG is higher than 100 and your taking oral, switch to transdermal...wait 6-8 weeks till it decreases by 20%...if it's still above 100, then lower the dosage. He likes it around 90. Oral estrogen really raises SHBG..therefore all the girls on BCP have sky-high SHBG...mine, on a pill, was way above 150...lab couldn't even measure it that high...off the pill, i'll know tomorrow..but i expect it to be lower...if it's not under 100 in another 6-8 weeks, i'll cut my E some...lynnelalala@... wrote: Lana writes: if you're taking any oral estrogen you need to switch to transdermal to lower SHBG...if you're already taking transdermal you need to take less of it to lower SHBG...higher E, higher SHBG..although SHBG binds T a lot more than it binds E... Lana, Do you have a source for this info? Dr. Uzzi Reiss writes about not taking oral or injectible in order to not raise SHBG. Other than that, I'd like to read more on the rest. Thanks, Lynne

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, i don't know for sure..but i'll definitely do some research tonight...what i did read in Vliet's book is that often low E co-incides with low thyroid...so i suspect there's a possibility that one could act as another, in E to thyroid relationship..but that's my speculations..more investigation is needed...SHBG is general is governed only by E, and not by any other hormones...oral E really pushes it up, cuz of the first passage through the liver thingy...it kinda fools the body to think that it's getting a LOT more E than what it really does..that's why often after dropping off BCP women still have low libido/hairloss 6 months after the fact...cuz their SHBG is still higher than normal...and while their body thinks there's plenty of estradiol available, there's not much of it in reality...Nuimom@... wrote: it was actually me, who posted this, ..and it's coming right from Reiss...he says that if your SHBG is higher than 100 and your taking oral, switch to transdermal...wait 6-8 weeks till it decreases by 20%...if it's still above 100, then lower the dosage. He likes it around 90. Oral estrogen really raises SHBG..therefore all the girls on BCP have sky-high SHBG...mine, on a pill, was way above 150...lab couldn't even measure it that high...off the pill, i'll know tomorrow..but i expect it to be lower...if it's not under 100 in another 6-8 weeks, i'll cut my E some...lynnelalala@... wrote: Lana writes: if you're taking any oral estrogen you need to switch to transdermal to lower SHBG...if you're already taking transdermal you need to take less of it to lower SHBG...higher E, higher SHBG..although SHBG binds T a lot more than it binds E... Lana, Do you have a source for this info? Dr. Uzzi Reiss writes about not taking oral or injectible in order to not raise SHBG. Other than that, I'd like to read more on the rest. Thanks, Lynne >>>>>>OK....here's a twist.....my SHBG went up when I got on ORAL thyroid meds????? Can it acts the same as oral E?????? Even when I had sky high transdermal E, my SHBG didn't jump up til the addition of oral thyroid!!!! Just wonder if anyone has seen this with their labs too???

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[Guest guest]

Does SHBG go up when Estrogen is high on an ongoing basis...like

when your own body produces it...or only when there is a sudden

spike (like during ovulation or when you start taking it

exogenously)?

At 02:45 PM 2/13/2006, you wrote:

if you're taking any oral

estrogen you need to switch to transdermal to lower SHBG...if you're

already taking transdermal you need to take less of it to lower

SHBG...higher E, higher SHBG..although SHBG binds T a lot more than it

binds E...

wrote:

Yes and then what? How do you lower the SHBG ? It's a

no-win

situation!

> >

>

> > question next time I go back -- how do they account

for such LOW

> > readings of E in our bloodstream if we ARE using 18

mgs a day?

>

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http://rhythmicliving.com/

**The group conversation is informational in nature and is not intended

as medical advice.**

[Guest guest]

I was under the impression that blood tests measure both bound and

unbound hormones COMBINED and that Saliva tests measure what is

unbound.

At 01:38 PM 2/13/2006, you wrote:

..... I think it's SHBG, sex

hormone binding globulin, that binds up elevated E so it isn't detected

in the blood. This is discovered by having an SHBG blood test....

Eileen

question next time I go back

-- how do they account for such LOW

readings of E in our bloodstream if we ARE using 18 mgs a day?

</blockquote></x-html>

[Guest guest]

that's correct, blood test measures total serum estradiol before it binds to SHBG and alubimrichkare@... wrote: I was under the impression that blood tests measure both bound and unbound hormones COMBINED and that Saliva tests measure what is unbound.At 01:38 PM 2/13/2006, you wrote: .... I think it's SHBG, sex hormone binding globulin, that binds up elevated E so it isn't detected in the blood. This is discovered by having an SHBG blood test.... Eileen question next time I go back -- how do they account for such LOW readings of E in our bloodstream if we ARE using 18 mgs a day?

</blockquote></x-html>

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[Guest guest]

hmm..that's a good question..i think as all the hormones it stays at a certain level, or close to it...when E in the body goes up, SHBG could get a tiny bit higher...but i am not too sure about this...richkare@... wrote: Does SHBG go up when Estrogen is high on an ongoing basis...like when your own body produces it...or only when there is a sudden spike (like during ovulation or when you start taking it exogenously)?At 02:45 PM 2/13/2006, you wrote: if you're taking any oral estrogen you need to switch to transdermal to lower SHBG...if you're already taking transdermal you need to take less of it to lower SHBG...higher E, higher SHBG..although SHBG binds T a lot more than it binds E... wrote: Yes and then

what? How do you lower the SHBG ? It's a no-win situation! > > > > > question next time I go back -- how do they account for such LOW > > readings of E in our bloodstream if we ARE using 18 mgs a day? >#define QUESTION ((bb) || !(bb)) - ShakespeareYahoo! MailUse Photomail to share photos without annoying attachments. click here for our webpage http://rhythmicliving.com/**The group conversation is informational in nature and is not intended as medical advice.**

[Guest guest]

I made the below post. And Lana, I have no idea how your name got on it. I take full responsibility for this info and can give the source if anyone would like it!. Sorry about this.Lana wrote:

Okay, I'm beginning to see how this happened. The snip above might suggest it's from Lana when it isn't. This has happened on other email groups I've been on.

Some of our email programs do not automatically reveal the name of the sender. So it is necessary to sign posts. Unless your name is obvious from your email address (@...) please sign.

Nobody did anything wrong. We just needed to sort out stuff. With the volume of email exchanged we run pretty smoothly. Is everybody happy?

Lynne

[Guest guest]

Lynne

No I did not write this!! I give NO advice...Read all of my orignial

posts not the cross posts (since bits and pieces get clipped...) I

have mentioned to others that I am learning and am not a dr.!!! I am

having a difficult time getting my own health in order

Everyone, please re-read MY posts-I did not tell anyone the below

statement and again I have NO clue about all of this since it is new

to me. This is the problem when posts aren't trimmed properly and

they stack up with others persons names on them...

Not mad here...just concerned that MY name is on the wrong post.

in peace and harmony,

Lana

>

>

> Lana writes:

>

> if you're taking any oral estrogen you need to switch to

transdermal to

> lower SHBG...if you're already taking transdermal you need to take

less of it to

> lower SHBG...higher E, higher SHBG..although SHBG binds T a lot

more than it

> binds E...

>

>

> Lana,

>

> Do you have a source for this info?

>

> Dr. Uzzi Reiss writes about not taking oral or injectible in order

to not

> raise SHBG. Other than that, I'd like to read more on the rest.

>

> Thanks,

> Lynne

>

[Guest guest]

I made the below post. And Lana, I have no idea how your name got on it. I take full responsibility for this info and can give the source if anyone would like it!. Sorry about this.Lana wrote: LynneNo I did not write this!! I give NO advice...Read all of my orignial posts not the cross posts (since bits and pieces get clipped...) I have mentioned to others that I am learning and am not a dr.!!! I am having a difficult time getting my own health in order Everyone, please re-read MY posts-I did not tell anyone the below statement and again I have NO clue about all of this since it is new to me. This is the problem when posts aren't trimmed properly and they stack up with others persons names on them...Not mad here...just concerned that MY name is on

the wrong post.in peace and harmony,Lana >> > Lana writes:> > if you're taking any oral estrogen you need to switch to transdermal to > lower SHBG...if you're already taking transdermal you need to take less of it to > lower SHBG...higher E, higher SHBG..although SHBG binds T a lot more than it > binds E...> > > Lana,> > Do you have a source for this info? > > Dr. Uzzi Reiss writes about not taking oral or injectible in order to not > raise SHBG. Other than that, I'd like to read more on the rest.> > Thanks,> Lynne>

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[Guest guest]

,

A big hug to ya-I over reacted! Can I blame my crappy state of health on this???

I know that you want to best for all of us

Lana

>> I made the below post. And Lana, I have no idea how your name got on it. I take full responsibility for this info and can give the source if anyone would like it!. Sorry about this.>

[Guest guest]

Lynne, Cool, all is well in the net" kingdom!!!

Lana

> > Okay, I'm beginning to see how this happened. The snip above might suggest > it's from Lana when it isn't. This has happened on other email groups I've > been on.> > Some of our email programs do not automatically reveal the name of the > sender. So it is necessary to sign posts. Unless your name is obvious from your > email address (_@..._ (mailto:@...) ) please sign.> > Nobody did anything wrong. We just needed to sort out stuff. With the volume > of email exchanged we run pretty smoothly. Is everybody happy? > > Lynne>

[Guest guest]

It's ok Trust me i totally understand Glad, it's all cleared now Btw, you've posted this morning that when you were on WP your hair was shedding more. I think it's normal for hair to shed more when they start to grow...cuz when you have problems with hair, like us, a lot of hairs are in telogen. As E kicks off new growth, the new hair push out the old ones...so the first thing we see is the increased shedding. I had it too when i first started BHRT...my shed is still not all the way down, but i have a lot of regrowth. A lot more than ever before. Hope this helps -Lana wrote: , A big hug to ya-I over reacted! Can I blame my crappy

state of health on this??? I know that you want to best for all of us Lana >> I made the below post. And Lana, I have no idea how your name got on it. I take full responsibility for this info and can give the source if anyone would like it!. Sorry about this.>

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It is reassuring and comforting which offers me hope-got to have that hope!!!

I have been in telogen effluvian (sp) for I swear it seems like a year, which is an eternity for hair. Lucky you-new hair!!! and I hope to reporting the same very soon-like yesterday. My Dr. reminds me that it will take time to see the effects of E and new hair and that patience, patience, patience is the name of the game.

Did you have major frontal scalp showing or just all over loss? Mine is so obvious above the crown and top rear of head and then diffuse all over the rest of the head.

Lana

> >> > I made the below post. And Lana, I have no idea how your name got on it. I take full responsibility for this info and can give the source if anyone would like it!. Sorry about this.> > > > > > click here for our webpage http://rhythmicliving.com/> > **The group conversation is informational in nature and is not intended as medical advice.** > > > >

[Guest guest]

Ya know..the problem is, now that i have some regrowth i am paranoid that it will all fall out...anxiety never stops! Btw, with high enough E you should see regrowth pretty quickly..i've noticed mine withint the first couple of weeks...ya knot in september my top was almost all bald..serious...more scalp than hair!!! and just as you most of my hair has been in telogen for quiet a while...even though the shedding was pretty fierce at once it's really slowing down now. Btw, i just got my blood work...that was done on the last day of progesterone...i took 50mg orally 1 hr before the test, and 100mg orally the night before... total testosterone: went up to 66 from 39 * i think P is really getting converted into T!!!* i am really scared here but my SHBG is not all the way down from BCP, so it's at 106 for the free T at 0.5 which is optimal estradiol is 189 *that's on 2 vivelle dot 0.1mg patches..i hoped for more...could it be that P lowers the amount of E in my blood?* some of my liver counts are higher than normal. Could it be because it's metabolizing P?! i am really disliking P right now. I've added a pump of estrogel to 2 vivelle dot patches and going to skip P next month altogether...Btw, i am not ovulating yet, as my FSH and my LH are both less than 1 and my progesterone is at 6.6, which isn't high..so i don't understand why is it being converted to T?! -Lana wrote: It is reassuring and comforting which offers me hope-got to have that hope!!! I have been in telogen effluvian (sp) for I swear it seems like a year, which is an eternity for hair. Lucky you-new hair!!! and I hope to reporting the same very soon-like yesterday. My Dr. reminds me that it will take time to see the effects of E and new hair and that patience, patience, patience is the name of the game. Did you have major frontal scalp showing or just all over loss? Mine is so obvious above the crown and top rear of head and then diffuse all over the rest of the head. Lana > >> > I made the below post. And Lana, I have no idea how your name got on it. I take full responsibility for this info and can give the source if anyone would like it!. Sorry about this.> > > > > > click here for our webpage

http://rhythmicliving.com/> > **The group conversation is informational in nature and is not intended as medical advice.** > > > >

[Guest guest]

,

Chocolate, is there anything that it can't do? Well, maybe make those tears go away. Do you have a good family support system? Here is a cyber tissue, now blow and blot.

Please do some reading up on androgen blockers and pregnancy!! You don't want to block hormones while pregnant-simply, you can't take those and. blockers while pregnant. And, if it were me, I would not take them while trying because sometimes we don't know that we are pregnant for a month or two down the line. *I did read this on the net on many sites w/regard to spiro and ald. and others...talk w/doc on that one...

You are having a lot to cope with for someone who should be dancing on clouds and looking forward to her marriage in 2 months. I hope that you can focus in on that, but I can sure understand all of your concerns. Hang in there, girl...

Glad that the P level is down.

Lana

> > > It is reassuring and comforting which offers me hope-got to > > have that hope!!!> > > > > > > > > > > > > > > > click here for our webpage http://rhythmicliving.com/> > > > **The group conversation is informational in nature and is not intended as medical advice.** > > > > > > > >

[Guest guest]

Karin, i am pretty sure that my lining is super thin after 10 yrs on BCP...the pill thins out the lining..that's why while on a pill the period will become less and less..i've been only supplementing with E for 8 weeks...so it hasn't really build up much..plus i was also supplementing with P...what i am going to do is to wait 3 weeks, and re-test estradiol, testosterone and FSH...i know i am still not ovulating..so if i get off E now, my hair will be exposed to a ton of T and NO E..that will kill it...i'll wait till after the wedding...if i won't start ovulating, then i'll first lower E some...if still nothing...i'll probably drop E...what i am wondering about is whether i can start ovulating if i am supplementing with E?! -J.bigbird3099 wrote: Hi ,Read all your posts and I know

your are feeling really frustrated. The fact that the sono showed your uterine lining as very thin shows that whatever E you are taking is not working (probably due to the spiro blocking the E). I have also heard from various compounding pharmacists that taking too much E turns off your E receptors. I think for now it is the spiro that is blocking the E. Have you ever thought of going off? (maybe after the wedding). I took no P this month and just got my period on day 29. The only thing I did differently this month was to put my patch close to the pubic area instead of my rear and I also took a little more E in the middle of my cycle. I think that all this is a process of some experimentation with your own body.Karin> > It is reassuring and comforting which offers me hope-got to > have that hope!!!> > > > > > > > click here for our webpage http://rhythmicliving.com/> > **The group conversation is informational in nature and is not intended as medical advice.** > > > >

[Guest guest]

I am not the expert, but I think it has more to do with the feedback loop. As

long as you

do not suppress that completely I think you can ovulate. If you read Uzzi Reiss'

book he

does not care for the BCP for various reasons and he felt the ideal Pill would

be made w/

bioidentical hormones but that you would have to take large amounts of these to

suppress

the ovaries. You may want to hit a peak w/your E sometime between day 10-12 and

just

take a smaller amount during the rest of the month. My daughter is on a steady

dose of

..25mg oral (Belmar) and just before her period this week she was getting hot

flashes and

the acne was not good. I personally see that as P (maybe not even a large

amount) that her

body is making blocking the E totally. I keep hoping her body will kick in on

its owen with

the E. She goes back to the Dr. in March. Oh another thing on aldactone is that

my

younger daughters pediatric endo says that he only uses it short term because he

has

found that it causes the ovaries to have more cysts.

Karin

> > > It is reassuring and comforting which offers me hope-got to

> > have that hope!!!

> >

> >

> >

> >

> >

> >

> >

> > click here for our webpage http://rhythmicliving.com/

> >

> > **The group conversation is informational in nature and is not intended as

medical

> advice.**

> >

> >

> >

> >