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  • 2 months later...

At 08:07 AM 10/29/2005 -0700, you wrote:

>Thought this would help add to the homeopathy thread.

>Perhaps we're influence too much by " main stream media "

http://www.quackwatch.org/01QuackeryRelatedTopics/holmes.html

Homeopathy and Its Kindred Delusions

Oliver Wendell Holmes

This essay were presented as two lectures to the

Boston Society for the Diffusion of Useful

Knowledge in 1842 and was reproduced in Examining

Holistic Medicine (Prometheus Books, 1985). The

author achieved prominence as a physician, poet,

and humorist. His son, Oliver Wendell Holmes,

Jr., became a justice of the U.S. Supreme Court.

----------

It is necessary, for the sake of those to whom

the whole subject may be new, to give in the

smallest possible compass the substance of the

Homeopathic Doctrine. Hahnemann, its

founder, is a German physician, now living in

Paris, at the age of eighty-seven years. In 1796

he published the first paper containing his

peculiar notions; in 1805 his first work on the

subject; in 1810 his somewhat famous " Organon of

the Healing Art; " the next year what he called

the " Pure Materia Medica; " and in 1828 his last

work, the " Treatise on Chronic Diseases. " He has

therefore been writing at intervals on his

favorite subject for nearly half a century. [Hahnemann died in 1843.]

The one great doctrine which constitutes the

basis of Homeopathy as a system is expressed by the Latin aphorism,

" SIMILIA SIMILIBUS CURANTUR, "

or like cures like, that is, diseases are cured

by agents capable of producing symptoms

resembling those found in the disease under

treatment. A disease for Hahnemann consists

essentially in a group of symptoms. The proper

medicine for any disease is the one which is

capable of producing a similar group of symptoms

when given to a healthy person.

It is of course necessary to know what are the

trains of symptoms excited by different

substances, when administered to persons in

health, if any such can be shown to exist.

Hahnemann and his disciples give catalogues of

the symptoms which they affirm were produced upon

themselves or others by a large number of drugs

which they submitted to experiment.

The second great fact which Hahnemann professes

to have established is the efficacy of medicinal

substances reduced to a wonderful degree of

minuteness or dilution. The following account of

his mode of preparing his medicines is from his

work on Chronic Diseases, which has not, I

believe, yet been translated into English. A

grain of the substance, if it is solid, a drop if

it is liquid, is to be added to about a third

part of one hundred grains of sugar of milk in an

unglazed porcelain capsule which has had the

polish removed from the lower part of its cavity

by rubbing it with wet sand; they are to be

mingled for an instant with a bone or horn

spatula, and then rubbed together for six

minutes; then the mass is to be scraped together

from the mortar and pestle, which is to take four

minutes; then to be again rubbed for six minutes.

Four minutes are then to be devoted to scraping

the powder into a heap, and the second third of

the hundred grains of sugar of milk to be added.

Then they are to be stirred an instant and rubbed

six minutes, again to be scraped together four

minutes and forcibly rubbed six; once more

scraped together for four minutes, when the last

third of the hundred grains of sugar of milk is

to be added and mingled by stirring with the

spatula; six minutes of forcible rubbing, four of

scraping together, and six more (positively the

last six) of rubbing, finish this part of the process.

Every grain of this powder contains the hundredth

of a grain of the medicinal substance mingled

with the sugar of milk. If, therefore, a grain of

the powder just prepared is mingled with another

hundred grains of sugar of milk, and the process

just described repeated, we shall have a powder

of which every grain contains the hundredth of

the hundredth, or the ten thousandth part of a'

grain of the medicinal substance. Repeat the same

process with the same quantity of fresh sugar of

milk, and every grain of your powder will contain

the millionth of a grain of the medicinal

substance. When the powder is of this strength,

it is ready to employ in the further solutions

and dilutions to be made use of in practice.

A grain of the powder is to be taken, a hundred

drops of alcohol are to be poured on it, the vial

is to be slowly turned for a few minutes, until

the powder is dissolved, and two shakes are to be

given to it. On this point I will quote

Hahnemann's own words. " A long experience and

multiplied observations upon the sick lead me

within the last few years to prefer giving only

two shakes to medicinal liquids, whereas I

formerly used to give ten. " The process of

dilution is carried on in the same way as the

attenuation of the powder was done; each

successive dilution with alcohol reducing the

medicine to a hundredth part of the quantity of

that which preceded it. In this way the dilution

of the original millionth of a grain of medicine

contained in the grain of powder operated on is

carried successively to the billionth,

trillionth, quadrillionth, quintillionth, and

very often much higher fractional divisions. A

dose of any of these medicines is a minute

fraction of a drop, obtained by moistening with

them one or more little globules of sugar, of

which Hahnemann says it takes about two hundred to weigh a grain.

As an instance of the strength of the medicines

prescribed by Hahnemann, I will mention carbonate

of lime. He does not employ common chalk, but

prefers a little portion of the friable part of

an oyster-shell. Of this substance, carried to

the sextillionth degree, so much as one or two

globules of the size mentioned can convey is a

common dose. But for persons of very delicate

nerves it is proper that the dilution should be

carried to the decillionth degree. That is, an

important medicinal effect is to be expected from

the two hundredth or hundredth part of the

millionth of the millionth of the millionth of

the millionth of the millionth of the millionth

of the millionth of the millionth of the

millionth of the millionth of a grain of

oyster-shell. This is only the tenth degree of

potency, but some of his disciples profess to

have obtained palpable effects from much higher dilutions.

The degrees of DILUTION must not be confounded

with those of POTENCY. Their relations may be wen by this table:

1st dilution -- One hundredth of a drop or grain.

2d dilution -- One ten thousandth.

3d dilution -- One millionth. -- marked I.

4th dilution -- One hundred millionth.

5th dilution -- One ten thousand millionth.

6th dilution -- One millionth millionth, or one billionth -- marked II.

7th dilution -- One hundred billionth.

8th dilution -- One ten thousand billionth.

9th dilution -- One million billionth, or one trillionth -- marked III.

10th dilution -- One hundred trillionth.

11th dilution -- One ten thousand trillionth.

12th dilution -- One million trillionth, or one

quadrillionth -- marked IV. -- and so on indefinitedly.

The large figures denote the degrees of POTENCY.

The third great doctrine of Hahnemann is the

following. Seven eighths at least of all chronic

diseases are produced by the existence in the

system of that infectious disorder known in the

language of science by the appellation of PSORA,

but to the less refined portion of the community

by the name of ITCH. in the words of Hahnemann's

" Organon, " " This Psora is the sole true and

fundamental cause that produces all the other

countless forms of disease, which, under the

names of nervous debility, hysteria,

hypochondriasis, insanity, melancholy, idiocy,

madness, epilepsy, and spasms of all kinds,

softening of the bones, or rickets, scoliosis and

cyphosis, caries, cancer, fungus haematodes, gout

-- yellow jaundice and cyanosis, dropsy --

gastralgia, epistaxis, haemoptysis -- asthma and

suppuration of the lungs -- megrim, deafness,

cataract and amaurosis -- paralysis, loss of

sense, pains of every kind, etc., appear in our

pathology as so many peculiar, distinct, and independent diseases. "

For the last three centuries, if the same

authority may be trusted, under the influence of

the more refined personal habits which have

prevailed, and the application of various

external remedies which repel the affection from

the skin, Psora has revealed itself in these

numerous forms of internal disease, instead of

appearing, as in former periods, under the aspect of an external malady.

These are the three cardinal doctrines of

Hahnemann, as laid down in those standard works

of Homeopathy, the " Organon " and the " Treatise on Chronic Diseases. "

Several other principles may be added, upon all

of which he insists with great force, and which

are very generally received by his disciples.

1. Very little power is allowed to the curative

efforts of nature. Hahnemann goes so far as to

say that no one has ever seen the simple efforts

of nature effect the durable recovery of a

patient from a chronic disease. In general, the

Homeopathist calls every recovery which happens under his treatment a cure.

2. Every medicinal substance must be administered

in a state of the most perfect purity, and

uncombined with any other. The union of several

remedies in a single prescription destroys its

utility, and, according to the " Organon, " frequently adds a new disease.

3. A large number of substances commonly thought

to be inert develop great medicinal powers when

prepared in the manner already described; and a

great proportion of them are ascertained to have

specific antidotes in case their excessive effects require to be neutralized.

4. Diseases should be recognized, as far as

possible, not by any of the common names imposed

upon them, as fever or epilepsy, but as

individual collections of symptoms, each of which

differs from every other collection.

5. The symptoms of any complaint must be

described with the most minute exactness, and so

far as possible in the patient's own words. To

illustrate the kind of circumstances the patient

is expected to record, I will mention one or two

from the 313th page of the " Treatise on Chronic

Diseases, " -- being the first one at which I opened accidentally.

" After dinner, disposition to sleep; the patient winks. "

" After dinner, prostration and feeling of

weakness (nine days after taking the remedy). "

This remedy was that same oyster-shell which is

to be prescribed in fractions of the sextillionth

or decillionth degree. According to Hahnemann,

the action of a single dose of the size mentioned

does not fully display itself in some cases until

twenty-four or even thirty days after it is

taken, and in such instances has not exhausted

its good effects until towards the fortieth or

fiftieth day,-before which time it would be

absurd and injurious to administer a new remedy.

----------

So much for the doctrines of Hahnemann, which

have been stated without comment, or exaggeration

of any of their features, very much as any

adherent of his opinions might have stated them,

if obliged to compress them into so narrow a space.

Does Hahnemann himself represent Homeopathy as it

now exists? He certainly ought to be its best

representative, after having created it, and

devoted his life to it for half a century. He is

spoken of as the great physician of the time, in

most, if not all Homeopathic works. If he is not

authority on the subject of his own doctrines,

who is? So far as I am aware, not one tangible

discovery in the so-called science has ever been

ascribed to any other observer, at least, no

general principle or law, of consequence enough

to claim any prominence in Homeopathic works, has

ever been pretended to have originated with any

of his illustrious disciples. He is one of the

only two Homeopathic writers with whom, as I

shall mention, the Paris publisher will have

anything to do with upon his own account. The

other is Jahr, whose Manual is little more than a

catalogue of symptoms and remedies. If any

persons choose to reject Hahnemann as not in the

main representing Homeopathy, if they strike at

his authority, if they wink out of sight his

deliberate and formally announced results, it is

an act of suicidal rashness; for upon his

sagacity and powers of observation, and

experience, as embodied in his works, and

especially in his Materia, Medica, repose the

foundations of Homeopathy as a practical system.

So far as I can learn from the conflicting

statements made upon the subject, the following

is the present condition of belief:

1. All of any note agree that the law Similia

similibus is the only fundamental principle in

medicine. Of course if any man does not agree to

this the name Homeopathist can no longer be applied to him with propriety.

2. The belief in and employment of the

infinitesimal doses is general, and in some

places universal, among the advocates of

Homeopathy; but a distinct movement has been made

in Germany to get rid of any restriction to the

use of these doses, and to employ medicines with

the same license as other practitioners.

3. The doctrine of the origin of most chronic

diseases in Psora, notwithstanding Hahnemann says

it cost him twelve years of study and research to

establish the fact and its practical

consequences, has met with great neglect and even

opposition from very many of his own disciples.

It is true, notwithstanding, that, throughout

most of their writings which I have seen, there

runs a prevailing tone of great deference to

Hahnemann's opinions, a constant reference to his

authority, a general agreement with the minor

points of his belief, and a pretense of

harmonious union in a common faith. [Those who

will take the trouble to look over Hull's

Translation of Jahr's Manual may observe how

little comparative space is given to remedies

resting upon any other authority than that of Hahnemann.]

* * *

The three great asserted discoveries of Hahnemann

are entirely unconnected with and independent of

each other. Were there any natural relation

between them it would seem probable enough that

the discovery of the first would have led to that

of the others. But assuming it to be a fact that

diseases are cured by remedies capable of

producing symptoms like their own, no manifest

relation exists between this fact and the next

assertion, namely, the power of the infinitesimal

doses. And allowing both these to be true,

neither has the remotest affinity to the third

new doctrine, that which declares seven eighths

of an chronic diseases to be owing to Psora.

* * *

Let us look a moment at the first of his

doctrines. Improbable though it may seem to some,

there is no essential absurdity involved in the

proposition that diseases yield to remedies

capable of producing like symptoms. There are, on

the other hand, some analogies which lend a

degree of plausibility to the statement. There

are well-ascertained facts, known from the

earliest periods of medicine, showing that, under

certain circumstances, the very medicine which,

from its known effects, one would expect to

aggravate the disease, may contribute to its

relief. I may be permitted to allude, in the most

general way, to the case in which the spontaneous

efforts of an overtasked stomach are quieted by

the agency of a drug which that organ refuses to

entertain upon any terms. But that every cure

ever performed by medicine should have been

founded upon this principle, although without the

knowledge of a physician; that the Homeopathic

axiom is, as Hahnemann asserts, " the sole law of

nature in therapeutics, " a law of which nothing

more than a transient glimpse ever presented

itself to the innumerable host of medical

observers, is a dogma of such sweeping extent,

and pregnant novelty, that it demands a

corresponding breadth and depth of unquestionable

facts to cover its vast pretensions.

So much ridicule has been thrown upon the

pretended powers of the minute doses that I shall

only touch upon this point for the purpose of

conveying, by illustrations, some shadow of ideas

far transcending the powers of the imagination to

realize. It must be remembered that these

comparisons are not matters susceptible of

dispute, being founded on simple arithmetical

computations, level to the capacity of any

intelligent schoolboy. A person who once wrote a

very small pamphlet made some show of objecting

to calculations of this kind, on the ground that

the highest dilutions could easily be made with a

few ounces of alcohol. But he should have

remembered that at every successive dilution he

lays aside or throws away ninety-nine hundredths

of the fluid on which he is operating, and that,

although he begins with a drop, he only prepares

a millionth, billionth, trillionth, and similar

fractions of it, all of which, added together,

would constitute but a vastly minute portion of

the drop with which he began. But now let us

suppose we take one single drop of the Tincture

of Camomile, and that the whole of this were to

be carried through the common series of dilutions.

A calculation nearly like the following was made

by Dr. Panvini, and may be readily followed in

its essential particulars by any one who chooses.

For the first dilution it would take 100 drops of alcohol.

For the second dilution it would take 10,000 drops, or about a pint.

For the third dilution it would take 100 pints.

For the fourth dilution it would take 10,000

pints, or more than 1,000 gallons, and so on to

the ninth dilution, which would take ten billion

gallons, which he computed would fill the basin

of Lake Agnano, a body of water two miles in

circumference. The twelfth dilution would of

course fill a million such lakes. By the time the

seventeenth degree of dilution should be reached,

the alcohol required would equal in quantity the

waters of ten thousand Adriatic seas. Trifling

errors must be expected, but they are as likely

to be on one side as the other, and any little

matter like Lake Superior or the Caspian would be but a drop in the bucket.

Swallowers of globules, one of your little

pellets, moistened in the mingled waves of one

million lakes of alcohol, each two miles in

circumference, with which had been blended that

one drop of Tincture of Camomile, would be of

precisely the strength recommended for that

medicine in your favorite Jahr's Manual, against

the most sudden, frightful, and fatal diseases!

[in the French edition of 1834, the proper doses

of the medicines are mentioned, and Camomile is

marked IV. Why are the doses omitted in Hull's

Translation, except in three instances out of the

whole two hundred remedies, notwithstanding the

promise in the preface that -some remarks upon

the doses used may be found at the head of each

medicine " ? Possibly because it makes no

difference whether they are employed in one

Homoeopathic dose or another; but then it is very

singular that such precise directions were

formerly given in the same work, and that

Hahnemann's " experience " should have led him to

draw the nice distinctions we have seen in a former part of this Lecture.]

And proceeding on the common data, I have just

made a calculation which shows that this single

drop of Tincture of Camomile, given in the

quantity ordered by Jahr's Manual, would have

supplied every individual of the whole human

family, past and present, with more than five

billion doses each, the action of each dose lasting about four days.

Yet this is given only at the quadrillionth, or

fourth degree of potency, and various substances

are frequently administered at the decillionth or

tenth degree, and occasionally at still higher

attenuations with professed medicinal results. is

there not in this as great an exception to all

the hitherto received laws of nature as in the

miracle of the loaves and fishes? Ask this

question of a Homeopathist, and he will answer by

referring to the effects produced by a very

minute portion of vaccine matter, or the

extraordinary diffusion of odors. But the vaccine

matter is one of those substances called morbid

poisons, of which it is a peculiar character to

multiply themselves, when introduced into the

system, as a seed does in the soil. Therefore the

hundredth part of a grain of the vaccine matter,

if no more than this is employed, soon increases

in quantity, until, in the course of about a

week, it is a grain or more, and can be removed

in considerable drops. And what is a very curious

illustration of Homeopathy, it does not produce

its most characteristic effects until it is

already in sufficient quantity not merely to be

visible, but to be collected for further use. The

thoughtlessness which can allow an inference to

be extended from a product of disease possessing

this susceptibility of multiplication when

conveyed into the living body, to substances of

inorganic origin, such as silex or sulphur, would

be capable of arguing that a pebble may produce a

mountain, because an acorn can become a forest.

As to the analogy to be found between the alleged

action of the infinitely attenuated doses, and

the effects of some odorous substances which

possess the extraordinary power of diffusing

their imponderable emanations through a very wide

space, however it may be abused in argument, and

rapidly as it evaporates on examination, it is

not like that just mentioned, wholly without

meaning. The fact of the vast diffusion of some

odors, as that of musk or the rose, for instance,

has long been cited as the most remarkable

illustration of the divisibility of matter, and

the nicety of the senses. And if this were

compared with the effects of a very minute dose

of morphia on the whole system, or the sudden and

fatal impression of a single drop of prussic

acid, or, with what comes still nearer, the

poisonous influence of an atmosphere impregnated

with invisible malaria, we should find in each of

these examples an evidence of the degree to which

nature, in some few instances, concentrates

powerful qualities in minute or subtile forms of

matter. But if a man comes to me with a pestle

and mortar in his hand, and tells me that he will

take a little speck of some substance which

nobody ever thought to have any smell at all, as,

for instance, a grain of chalk or of charcoal,

and that he will, after an hour or two of rubbing

and scraping, develop in a portion of it an odor

which, if the whole grain were used, would be

capable of pervading an apartment, a house, a

village, a province, an empire, nay, the entire

atmosphere of this broad planet upon which we

tread, and that from each of fifty or sixty

substances he can in this way develop a distinct

and hitherto unknown odor; and if he tries to

show that all this is rendered quite reasonable

by the analogy of musk and roses, I shall

certainly be justified in considering him

incapable of reasoning, and beyond the reach of

my argument. what if, instead of this, he

professes to develop new and wonderful medicinal

powers from the same speck of chalk or charcoal,

in such proportions as would impregnate every

pond, lake, river, sea, and ocean of our globe,

and appeals to the same analogy in favor of the probability of his assertion.

All this may be true, notwithstanding these

considerations. But so extraordinary would be the

fact, that a single atom of substances which a

child might swallow without harm by the

teaspoonful could, by an easy mechanical process,

be made to develop such inconceivable powers,

that nothing but the strictest agreement of the

most cautious experimenters, secured by every

guaranty that they were honest and faithful,

appealing to repeated experiments in public, with

every precaution to guard against error, and with

the most plain and peremptory results, should

induce us to lend any credence to such pretensions.

The third doctrine, that Psora, the other name of

which you remember, is the cause of the great

majority of chronic diseases, is a startling one,

to say the least. That an affection always

recognized as a very unpleasant personal

companion, but generally regarded as a mere

temporary incommodity, readily yielding to

treatment in those unfortunate enough to suffer

from it, and hardly known among the better

classes of society, should be all at once found

out by a German physician to be the great scourge

of mankind, the cause of their severest bodily

and mental calamities, cancer and consumption,

idiocy and madness, must excite our unqualified

surprise. And when the originator of this

singular truth ascribes, as in this page now open

before me, the declining health of a disgraced

courtier, the chronic malady of a bereaved

mother, even the melancholy of the love-sick and

slighted maiden, to nothing more nor less than

the insignificant, unseemly, and almost

unmentionable ITCH, does it not seem as if the

very soil upon which we stand were dissolving

into chaos, over the earthquake-heaving of discovery?

And when one man claims to have established these

three independent truths, which are about as

remote from each other as the discovery of the

law of gravitation, the invention of printing,

and that of the mariner's compass, unless the

facts in their favor are overwhelming and

unanimous, the question naturally arises, Is not

this man deceiving himself, or trying to deceive others?

I proceed to examine the proofs of the leading

ideas of Hahnemann and his school.

In order to show the axiom, similia similibus

curantur (or like is cured by like), to be the

basis of the healing art -- " the sole law of

nature in therapeutics " -- it is necessary --

1. That the symptoms produced by drugs in healthy

persons should be faithfully studied and recorded.

2. That drugs should be shown to be always

capable of curing those, diseases most like their own symptoms.

3. That remedies should be shown not to cure

diseases when they do not produce symptoms

resembling those presented in these diseases.

----------

1. The effects of drugs upon healthy persons have

been studied by Hahnemann and his associates.

Their results were made known in his Materia

Medica, a work in three large volumes in the

French translation, published about eight years

ago. The mode of experimentation appears to have

been, to take the substance on trial, either in

common or minute doses, and then to set down

every little sensation, every little movement of

mind or body, which occurred within many

succeeding hours or days, as being produced

solely by the substance employed. When I have

enumerated some of the symptoms attributed to the

power of the drugs taken, you will be able to

judge how much value is to be ascribed to the assertions of such observers.

The following list was taken literally from the

Materia Medica of Hahnemann, by my friend M.

Vernois, for whose accuracy I am willing to be

responsible. He has given seven pages of these

symptoms, not selected, but taken at hazard from

the French translation of the work. I shall be very brief in my citations.

" After stooping some time, sense of painful

weight about the head upon resuming the erect posture. "

" An itching, tickling sensation at the outer edge

of the palm of the left hand, which obliges the

person to scratch. " The medicine was acetate of

lime, and as the action of the globule taken is

said to last twenty-eight days, you may judge how

many such symptoms as the last might be supposed to happen.

Among the symptoms attributed to muriatic acid

are these: a catarrh, sighing, pimples; " after

having written a long time with the back a little

bent over, violent pain in the back and

shoulder-blades, as if from a strain, " -- " dreams

which are not remembered -- disposition to mental

dejection -- wakefulness before and after midnight. "

I might extend this catalogue almost

indefinitely. I have not cited these specimens

with any view to exciting a sense of the

ridiculous, which many others of those mentioned

would not fail to do, but to show that the common

accidents of sensation, the little bodily

inconveniences to which all of us are subject,

are seriously and systematically ascribed to

whatever medicine may have been exhibited, even

in the minute doses I have mentioned, whole days or weeks previously.

To these are added all the symptoms ever said by

anybody, whether deserving confidence or not, as

I shall hereafter illustrate, to be produced by the substance in question.

The effects of sixty-four medicinal substances,

ascertained by one or both of these methods, are

enumerated in the Materia Medica of Hahnemann,

which May be considered as the basis of practical

Homeopathy. In the Manual of Jahr, which is the

common guide, so far as I know, of those who

practise Homeopathy in these regions, two hundred

remedies are enumerated, many Of which, however,

have never been employed in practice. In at least

one edition there were no means of distinguishing

those which had been tried upon the sick from the

others. It is true that marks have been added in

the edition employed here, which serve to

distinguish them; but what are we to think of a

standard practical author on Materia Medica, who

at one time omits to designate the proper doses

of his remedies, and at another to let us have

any means of knowing whether a remedy has ever

been tried or not, while he is recommending its

employment in the most critical and threatening diseases?

I think that, from what I have shown of the

character of Hahnemann's experiments, it would be

a satisfaction to any candid inquirer to know

whether other persons, to whose assertions he

could look with confidence, confirm these

pretended facts. Now there are many individuals,

long and well known to the scientific world, who

have tried these experiments upon healthy

subjects, and utterly deny that their effects

have at all corresponded to Hahnemann's assertions.

I will take, for instance, the statements of

Andral (and I am not referring to his well-known

public experiments in his hospital) as to the

result of his own trials. This distinguished

physician is Professor of Medicine in the School

of Paris, and one of the most widely known and

valued authors upon practical and theoretical

subjects the profession can claim in any country.

He is a man of great kindness of character, a

most liberal eclectic by nature and habit, of

unquestioned integrity, and is called, in the

leading article of the fast number of the

" Homeopathic Examiner, " " an eminent and very

enlightened allopathist. " Assisted by a number of

other persons in good health, he experimented on

the effects of cinchona, aconite, sulphur,

arnica, and the other most highly extolled

remedies. His experiments lasted a year, and he

stated publicly to the Academy of Medicine that

they never produced the slightest appearance of

the symptoms attributed to them. The results of a

man like this, so extensively known as one of the

most philosophical and candid, as well as

brilliant of instructors, and whose admirable

abilities and signal liberality are generally

conceded, ought to be of great weight in deciding the question.

M. Double, a well-known medical writer and a

physician of high standing in Paris, had occasion

so long ago as 1801, before he had heard of

Homeopathy, to make experiments upon Cinchona, or

Peruvian bark. He and several others took the

drug in every kind of dose for four months, and

the fever it is pretended by Hahnemann to excite never was produced.

M. Bonnet, President of the Royal Society of

Medicine of Bordeaux, had occasion to observe

many soldiers during the Peninsular War, who made

use of Cinchona as a preservative against

different diseases,-but he never found it to produce the pretended paroxysms.

If any objection were made to evidence of this

kind, I would refer to the express experiments on

many of the Homeopathic substances, which were

given to healthy persons with every precaution as

to diet and regimen, by M Louis Fleury, without

being followed by the slightest of the pretended

consequences. And let me mention as a curious

fact, that the same quantity of arsenic given to

one animal in the common form of the unprepared

powder, and to another after having been rubbed

up into six hundred globules, offered no

particular difference of activity in the two

cases. This is a strange contradiction to the

doctrine of the development of what they call

dynamic power, by means of friction and subdivision.

In 1835 a public challenge was offered to the

best-known Homeopathic physician in Paris to

select any ten substances asserted to produce the

most striking effects; to prepare them himself;

to choose one by lot without knowing which of

them he had taken, and try it upon himself or an

intelligent and devoted Homeopathist, and,

waiting his own time, to come forward and tell

what substance had been employed. The challenge

was at first accepted, but the acceptance

retracted before the time of trial arrived.

From all this I think it fair to conclude that

the catalogues of symptoms attributed in

Homeopathic works to the influence of various

drugs upon healthy persons are not entitled to any confidence.

----------

2. It is necessary to show, in the next place,

that medicinal substances are always capable of

curing diseases most like their own symptoms. For

facts relating to this question we must look to

two sources; the recorded experience of the

medical profession in general, and the results of

trials made according to Homeopathic principles,

and capable of testing the truth of the doctrine.

No person, that I am aware of, has ever denied

that in some cases there exists a resemblance

between the effects of a remedy and the symptoms

of diseases in which it is beneficial. This has

been recognized, as Hahnemann himself has shown,

from the time of Hippocrates. But according to

the records of the Medical profession, as they

have been hitherto interpreted, this is true of

only a very small proportion of useful remedies.

Nor has it ever been considered as an established

truth that the efficacy of even these few

remedies was in any definite ratio to their power

of producing symptoms more or less like those they cured.

Such was the state of opinion when Hahnemann came

forward with the proposition that all the cases

of successful treatment found in the works of all

preceding medical writers were to be ascribed

solely to the operation of the Homeopathic

principle, which had effected the cure, although

without the physician's knowledge that this was

the real secret. And strange as it may seem he

was enabled to give such a degree of plausibility

to this assertion, that any Person not acquainted

somewhat with medical literature, not quite

familiar, I should rather say, with the relative

value of medical evidence, according to the

Sources whence it is derived, would be almost

frightened into the belief, at seeing the pages

upon pages of Latin names he has summoned as his witnesses.

It has hitherto been customary, when examining

the writings of authors of Preceding ages, upon

subjects as to which they were less enlightened

than ourselves, and which they were very liable

to misrepresent, to exercise some little

discretion; to discriminate, in some measure,

between writers deserving confidence and those

not entitled to it. But there is not the least

appearance of any such delicacy on the part of

Hahnemann. A large majority of the names of old

authors he cites are wholly unknown to science.

With some of them I have been long acquainted,

and I know that their accounts of diseases are no

more to be trusted than their contemporary

Ambroise Paré stories of mermen, and similar

absurdities. But if my judgment is rejected, as

being a prejudiced one, I can refer to Cullen,

who mentioned three of Hahnemann's authors in one

sentence, as being " not necessarily bad

authorities; but certainly such when they

delivered very improbable events; " and as this

was said more than half a century ago, it could

not have had any reference to Hahnemann. But

although not the slightest sign of discrimination

is visible in his quotations -- although for him

a handful of chaff from Schenck is all the same

thing as a measure of wheat from Morgagni --

there is a formidable display of authorities, and

an abundant proof of ingenious researches to be

found in each of the great works of Hahnemann with which I am familiar.

It is stated by Dr. Leo-Wolf, that Professor

Joerg, of Leipsic, has proved many of Hahnemann's

quotations from old authors to be adulterate and

false. What particular instances he has pointed

out I have no means of learning. And it is

probably wholly impossible on this side of the

Atlantic, and even in most of the public

libraries of Europe, to find anything more than a

small fraction of the innumerable obscure

publications which the neglect of grocers and

trunk-makers has spared to be ransacked by the

all-devouring genius of Homeopathy. I have

endeavored to verify such passages as my own

library afforded me the means of doing. For some

I have looked in vain, for want, as I am willing

to believe, of more exact references. But this I

am able to affirm, that, out of the very small

number which I have been able to trace back to

their original authors, I have found two to be

wrongly quoted, one of them being a gross misrepresentation.

The first is from the ancient Roman author,

Caelius Aurelianus; the second from the venerable

folio of Forestus. Hahnemann uses the following

expressions,-if he is not misrepresented in the

English Translation of the " Organon " :

" Asclepiades on one occasion cured an

inflammation of the brain by administering a

small quantity of wine. " After correcting the

erroneous reference of the Translator, I can find

no such case alluded to in the chapter. But

Caelius Aurelianus, mentions two modes of

treatment employed by Asclepiades, into both of

which the use of wine entered, as being in the

highest degree irrational and dangerous [Caelius

Aurel De Morb. Acut. et Chron. lib. 1. cap. xv,

not xvi. Amsterdam. Wetstein, 1755].

In speaking of the oil of anise-seed, Hahnemann

says that Forestus observed violent colic caused

by its administration. But, as the author tells

the story, a young man took, by the counsel of a

surgeon, an acrid and virulent medicine, the name

of which is not given, which brought on a most

cruel fit of the gripes and colic. After this

another surgeon was called, who gave him oil of

anise-seed and wine, which increased his

suffering [Observ. et Curat. Med. lib. XXI. obs.

xiii. fort, 1614]. Now if this was the

Homeopathic remedy, as Hahnemann pretends, it

might be a fair question why the young man was

not . cured by it. But it is a much graver

question why a man who has shrewdness and

learning enough to go so far after his facts,

should think it right to treat them with such

astonishing negligence or such artful unfairness.

Even if every word he had pretended to take from

his old authorities were to be found in them,

even if the authority of every one of these

authors were beyond question, the looseness with

which they are used to prove whatever Hahnemann

chooses is beyond the bounds of credibility. Let

me give one instance to illustrate the character

of this man's mind. Hahnemann asserts, in a note

annexed to the 110th paragraph of the " Organon, "

that the smell of the rose will cause certain

persons to faint. And he says in the text that

substances which produce peculiar effects of this

nature on particular constitutions cure the same

symptoms in people in general. Then in another

note to the same paragraph he quotes the

following fact from one of the last sources one

would have looked to for medical information, the Byzantine Historians.

" It was by these means " (i.e. Homeopathically)

" that the Princess Eudosia with rose-water restored a person who had fainted! "

Is it possible that a man who is guilty of such

pedantic folly as this,-a man who can see a

confirmation of his doctrine in such a recovery

as this -- a recovery which is happening every

day, from a breath of air, a drop or two of

water, untying a bonnet-string, loosening a

stay-lace, and which can hardly help happening,

whatever is done -- is it possible that a man, of

whose pages, not here and there one, but hundreds

upon hundreds are loaded with such trivialities,

is the Newton, the Columbus, the Harvey of the nineteenth century!

The whole process of demonstration he employs is

this. An experiment is instituted with some drug

upon one or more healthy persons. Everything that

happens for a number of days or weeks is, as we

have seen, set down as an effect of the medicine.

Old volumes are then ransacked promiscuously, and

every morbid sensation or change that anybody

ever said was produced by the drug in question is

added to the list of symptoms. By one or both of

these methods, each of the sixty-four substances

enumerated by Hahnemann is shown to produce a

very large number of symptoms, the lowest in his

scale being ninety-seven, and the highest

fourteen hundred and ninety-one. And having made

out this fist respecting any drug, a catalogue

which, as you may observe in any Homeopathic

manual, contains various symptoms belonging to

every organ of the body, what can be easier than

to find alleged cures in every medical author

which can at once be attributed to the

Homeopathic principle; still more if the grave of

extinguished credulity is called upon to give up

its dead bones as living witnesses; and worst of

all, if the monuments of the past are to be

mutilated in favor of " the sole law of Nature in therapeutics " ?

There are a few familiar facts of which great use

has been made as an entering wedge for the

Homeopathic doctrine. They have been suffered to

pass current so long that it is time they should

be nailed to the counter, a little operation

which I undertake, with perfect cheerfulness, to perform for them.

The first is a supposed illustration of the

Homeopathic law found in the precept given for

the treatment of parts which have been frozen, by

friction with snow or similar means. But we

deceive ourselves by names, if we suppose the

frozen part to be treated by cold, and not by

heat. The snow may even be actually warmer than

the part to which it is applied. But even if it

were at the same temperature when applied, it

never did and never could do the least good to a

frozen part, except as a mode of regulating the

application of what? of heat. But the heat must

be applied gradually, just as food must be given

a little at a time to those perishing with

hunger. If the patient were brought into a warm

room, heat would be applied very rapidly, were

not something interposed to prevent this, and

allow its gradual admission. Snow or iced water

is exactly what is wanted; it is not cold to the

part; it is very possibly warm, on the contrary,

for these terms are relative, and if it does not

melt and let the heat in, or is not taken away,

the part will remain frozen up until doomsday.

Now the treatment of a frozen limb by heat, in

large or small quantities, is not Homoeopathy.

The next supposed illustration of the

Homoeopathic law is the alleged successful

management of burns, by holding them to the fire.

This is a popular mode of treating those burns

which are of too little consequence to require

any more efficacious remedy, and would inevitably

get well of themselves, without any trouble being

bestowed upon them. It produces a most acute pain

in the part, which is followed by some loss of

sensibility, as happens with the eye after

exposure to strong light, and the ear after being

subjected to very intense sounds. This is all it

is capable of doing, and all further notions of

its efficacy must be attributed merely to the

vulgar love of paradox. If this example affords

any comfort to the Homoeopathist, it seems as

cruel to deprive him of it as it would be to

convince the mistress of the smoke-jack or the

flat-iron that the fire does not literally " draw

the fire out, " which is her hypothesis.

But if it were true that frost-bites were cured

by cold and bums by heat, it would be subversive,

so far as it went, of the great principle of

Homoeopathy. For you will remember that this

principle is that Like cures Like, and not that

Same cures Same; that there is resemblance and

not identity between the symptoms of the disease

and those produced by the drug which cures it,

and none have been readier to insist upon this

distinction than the Homoeopathists themselves.

For if Same cures Same, then every poison must be

its own antidote, which is neither a part of

their theory nor their so-called experience. They

have been asked often enough, why it was that

arsenic could not cure the mischief which arsenic

had caused, and why the infectious cause of

small-pox did not remedy the disease it had

produced, and then they were ready enough to see

the distinction I have pointed out. O no! it was

not the hair of the same dog, but only of one very much like him!

A third instance in proof of the Homoeopathic law

is sought for in the acknowledged efficacy of

vaccination. And how does the law apply to this?

It is granted by the advocates of Homoeopathy

that there is a resemblance between the effects

of the vaccine virus on a person in health and

the symptoms of smallpox. Therefore, according to

the rule, the vaccine virus will cure the

small-pox which, as everybody knows, is entirely

untrue. But it prevents small-pox, say the

Homoeopathists. Yes, and so does small-pox

prevent itself from ever happening again, and we

know just as much of the principle involved in

the one caw as in the other. For this is only one

of a series of facts which we are wholly unable

to explain. Small-pox, measles, scarlet-fever,

hooping-cough, protect those who have them once

from future attacks; but nettle-rash and catarrh

and lung fever,- each of which is just as

Homoeopathic to itself as any one of the others,

have no such preservative power. We are obliged

to accept the fact, unexplained, and we can do no

more for vaccination than for the rest.

I come now to the most directly practical point

connected with the subject, namely --

What is the state of the evidence as to the

efficacy of the proper Homoeopathic treatment in the cure of diseases.

As the treatment adopted by the Homoeopathists

has been almost universally by means of the

infinitesimal doses, the question of their

efficacy is thrown open, in common with that of

the truth of their fundamental axiom, as both are tested in practice.

We must look for facts as to the actual working

of Homoeopathy to three sources.

1. The statements of the unprofessional public.

2. The assertions of Homoeopathic practitioners.

3. The results of trials by competent and honest

physicians, not pledged to the system.

I think, after what we have seen of medical

facts, as they are represented by incompetent

persons, we are disposed to attribute little

value to all statements of wonderful cures,

coming from those who have never been accustomed

to watch the caprices of disease, and have not

cooled down their young enthusiasm by the habit

of tranquil observation. Those who know nothing

of the natural progress of a malady, of its

ordinary duration, of its various modes of

terminating, of its liability to accidental

complications, of the signs which mark its

insignificance or severity, of what is to be

expected of it when left to itself, of how much

or how little is to be anticipated from remedies,

those who know nothing or next to nothing of all

these things, and who are in a great state of

excitement from benevolence, sympathy, or zeal

for a new medical discovery, can hardly be

expected to be sound judges of facts which have

misled so many sagacious men, who have spent

their lives in the daily study and observation of

them. I believe that, after having drawn the

portrait of defunct Perkinism, with its rive

thousand printed cures, and its million and a

half computed ones, its miracles blazoned about

through America, Denmark, and England; after

relating that forty years ago women carried the

Tractors about in their pockets, and workmen

could not make them fast enough for the public

demand; and then showing you, as a curiosity, a

single one of these instruments, an odd 6ne of a

pair, which I obtained only by a lucky accident,

so utterly lost is the memory of all their

wonderful achievements; I believe, after all

this, I need not waste time in showing that

medical accuracy is not to be looked for in the

florid reports of benevolent associations, the

assertions of illustrious patrons, the lax

effusions of daily journals, or the effervescent gossip of the tea-table.

Dr. Hering, whose name is somewhat familiar to

the champions of Homoeopathy, has said that " the

new healing art is not to be judged by its

success in isolated cases only, but according to

its success in general, its innate truth, and the

incontrovertible nature of its innate principles. "

We have seen something of " the incontrovertible

nature of its innate principles, " and it seems

probable, on the whole, that its success in

general must be made up of its success in

isolated cases. Some attempts have been made,

however, to finish the whole matter by sweeping

statistical documents, which are intended to

prove its triumphant success over the common practice.

It is well known to those who have had the good

fortune to see the " Homoeopathic Examiner, " that

this journal led off, in its first number, with a

grand display of everything the newly imported

doctrine had to show for itself. It is well

remarked, on the twenty-third page of this

article, that " the comparison of bills of

mortality among an equal number of sick, treated

by divers methods, is a most poor and lame way to

get at conclusions touching principles of the

healing art. " In confirmation of which, the

author proceeds upon the twenty-fifth page to

prove the superiority of the Homoeopathic

treatment of cholera, by precisely these very

bills of mortality. Now, every intelligent

physician is aware that the poison of cholera

differed so much in its activity at different

times and places, that it was next to impossible

to form any opinion as to the results of

treatment, unless every precaution was taken to

secure the most perfectly corresponding

conditions in the patients treated, and hardly

even then. Of course, then, a Russian Admiral, by

the name of Mordvinow, backed by a number of

so-called physicians practising in Russian

villages, is singularly competent to the task of

settling the whole question of the utility of

this or that kind of treatment; to prove that, if

not more than eight and a half per cent of those

attacked with the disease perished, the rest owed

their immunity to Hahnemann. I can remember when

more than a hundred patients in a public

institution were attacked with what, I doubt not,

many Homoeopathic physicians (to say nothing of

Homoeopathic admirals) would have called cholera,

and not one of them died, though treated in the

common way, and it is my firm belief that, if

such a result had followed the administration of

the omnipotent globules, it would have been in

the mouth of every adept in Europe, from Quin of

London to Spohr of Gandersheim. No longer ago

than yesterday, in one of the most widely

circulated papers of this city, there was

published an assertion that the mortality in

several Homoeopathic Hospitals was not quite five

in a hundred, whereas, in what am called by the

writer Allopathic Hospitals, it is said to be

eleven in a hundred. An honest man should be

ashamed of such an argumentum ad ignorandam. The

mortality of a hospital depends not merely on the

treatment of the patients, but on the class of

diseases it is in the habit of receiving on the

place where it is, on the season, and many other

circumstances. For instance, them are many

hospitals in the great cities of Europe that

receive few diseases of a nature to endanger

life, and, on the other hand, there are others

where dangerous diseases are accumulated out of

the common proportion. Thus, in the wards of

Louis, at the Hospital of La Pitia, a vast number

of patients in the last stages of consumption

were constantly entering, to swell the mortality

of that hospital. It was because he was known to

pay particular attention to the diseases of the

chest that patients laboring under those fatal

affections to an incurable extent were so

constantly coming in upon him. It is always a

miserable appeal to the thoughtlessness of the

vulgar, to allege the naked fact of the less

comparative mortality in the practice of one

hospital or of one physician than another, as an

evidence of the superiority of their treatment.

Other things being equal, it must always be

expected that those institutions and individuals

enjoying to the highest degree the confidence of

the community will lose the largest proportion of

their patients; for the simple reason that they

will naturally be looked to by those suffering

from the gravest class of diseases; that many,

who know that they are affected with mortal

disease, will choose to die under their care or

shelter, while the subjects of trifling maladies,

and merely troublesome symptoms, amuse themselves

to any extent among the fancy practitioners.

When, therefore, Dr. Muhlenbein, as stated in the

" Homoeopathic Examiner, " and quoted in

yesterday's " Daily Advertiser, " asserts that the

mortality among his patients is only one per cent

since he has practised Homoeopathy, whereas it

was six per cent when he employed the common mode

of practice, I am convinced by this, his own

statement, that the citizens of Brunswick,

whenever they are seriously sick, take good care

not to send for Dr. Muhlenbein!

It is evidently impossible that I should attempt,

within the compass of a single lecture, any

detailed examination of the very numerous cases

reported in the Homoeopathic Treatises and

Journals. Having been in the habit of receiving

the French " Archives of Homoeopathic Medicine "

until the premature decease of that Journal, I

have had the opportunity of becoming acquainted

somewhat with the style of these documents, and

experiencing whatever degree of conviction they

were calculated to produce. Although of course I

do not wish any value to be assumed for my

opinion, such as it is, I consider that you are

entitled to hear it. So far, then, as I am

acquainted with the general character of the

cases reported by the Homoeopathic physicians,

they would for the most part be considered as

wholly undeserving a place in any English,

French, or America periodical of high standing

if, instead of favoring the doctrine they were

intended to support, they were brought forward to

prove the efficacy of any common remedy

administered by any common practitioner. There

are occasional exceptions to this remark; but the

general truth of it is rendered probable by the

fact that these cases are always, or almost

always, written with the single object of showing

the efficacy of the medicine used, or the skill

of the practitioner, and it is recognized as a

general rule that such cases deserve very little

confidence. Yet they may sound well enough, one

at a time, to those who are not fully aware of

the fallacies of medical evidence. Let me state a

case in illustration. Nobody doubts that some

patients recover under every form of practice.

Probably all are willing to allow that a large

majority, for instance, ninety in a hundred, of

such cases as a physician is called to in daily

practice, would recover, sooner or later, with

more or less difficulty, provided nothing were

done to interfere seriously with the efforts of nature.

Suppose, then, a physician who has a hundred

patients prescribes to each of them pills made of

some entirely inert substance, as starch, for

instance. Ninety of them get well, or if he

chooses to use such language, he cures ninety of

them. It is evident, according to the doctrine of

chances, that there must be a considerable number

of coincidences between the relief of the patient

and the administration of the remedy. It is

altogether probable that there will happen two or

three very striking coincidences out of the whole

ninety cases, in which it would seem evident that

the medicine produced the relief, though it had,

as we assumed, nothing to do with it. Now.

suppose that the physician publishes these cases,

will they not have a plausible appearance of

proving that which, as we granted at the outset,

was entirely false? Suppose that instead of pills

of starch he employs microscopic sugarplums, with

the five million billion trillionth part of a

suspicion of aconite or pulsatilla, and then

publishes his successful cases, through the

leaden lips of the press, or the living ones of

his female acquaintances,-does that make the

impression a less erroneous one? But so it is

that in Homoeopathic works and journals and

gossip one can never, or next to never, find

anything but successful cases, which might do

very well as a proof of superior skill, did it

not prove as much for the swindling advertisers

whose certificates disgrace so many of our

newspapers. How long will it take mankind to

learn that while they listen to " the speaking

hundreds and units, who make the world ring " with

the pretended triumphs they have witnessed, the

" dumb millions " of deluded and injured victims

are paying the daily forfeit of their misplaced confidence!

I am sorry to see, also, that a degree of

ignorance as to the natural course of diseases is

often shown in these published cases, which,

although it may not be detected by the

unprofessional reader, conveys an unpleasant

impression to those who are acquainted with the

subject. Thus a young woman affected with

jaundice is mentioned in the German " ls of

Clinical Homoeopathy " as having been cured in

twenty-nine days by pulsatilla and nux vomica.

Rummel, a well-known writer of the same school,

speaks of curing a case of jaundice in

thirty-four days by Homoeopathic doses of

pulsatilla, aconite, and cinchona. I happened to

have a case in my own household, a few weeks

since, which lasted about ten days, and this was

longer than I have repeatedly seen it in hospital

practice, so that it was nothing to boast of.

Dr. Munneche of Lichtenburg in Saxony is called

to a patient with a sprained ankle who had been a

fortnight under the common treatment. The patient

gets well by the use of arnica in a little more

than a month longer, and this extraordinary fact

is published in the French " Archives of Homoeopathic Medicine. "

In the same journal is recorded the case of a

patient who with nothing more, so far as any

proof goes, than influenza, gets down to her shop upon the sixth day.

And again, the cool way in which everything

favorable in a case is set down by these people

entirely to their treatment, may be seen in a

case of croup reported in the " Homoeopathic

Gazette " of Leipsic, in which leeches,

blistering, inhalation of hot vapor, and powerful

internal medicine had been employed, and yet the

merit was all attributed to one drop of some Homoeopathic fluid.

I need not multiply these quotations, which

illustrate the grounds of an opinion which the

time does not allow me to justify more at length;

other such cases are lying open before me; there

is no end to them if more were wanted; for

nothing is necessary but to look into any of the

numerous broken-down Journals of Homoeopathy, the

volumes of which may be found on the shelves of those curious in such matters.

A number of public trials of Homoeopathy have

been made in different parts of the world. Six of

these are mentioned in the Manifesto of the

" Homoeopathic Examiner. " Now to suppose that any

trial can absolutely silence people, would be to

forget the whole experience of the past. Dr.

Haygarth and Dr. Alderson could not stop the sale

of the five-guinea Tractors, although they proved

that they could work the same miracles with

pieces of wood and tobacco-pipe. It takes time

for truth to operate as well as Homoeopathic

globules. Many persons thought the results of

these trials were decisive enough of the nullity

of the treatment; those who wish to see the kind

of special pleading and evasion by which it is

attempted to cover results which, stated by the

" Homoeopathic Examiner " itself, look exceedingly

like a miserable failure, may consult the opening

flourish of that Journal. I had not the intention

to speak of these public trials at all, having

abundant other evidence on the point. But I think

it best, on the whole, to mention two of them in

a few words -- that instituted at Naples and that of Andral.

There have been few names in the medical

profession, for the last half century, so widely

known throughout the world of science as that of

M. Esquirol, whose life was devoted to the

treatment of insanity, and who was without a

rival in that department of practical medicine.

It is from an analysis communicated by him to the

" Gazette Médicale de Paris " that I derive my

acquaintance with the account of the trial at

Naples by Dr. Panvini, physician to the Hospital

della Pace. This account seems to be entirely

deserving of credit. Ten patients were set apart,

and not allowed to take any medicine at all,-Much

against the wish of the Homoeopathic physician.

All of them got well, and of course all of them

would have been claimed as triumphs if they had

been submitted to the treatment. Six other slight

cases (each of which is specified) got well under

the Homoeopathic treatment -- none of its

asserted specific effects being manifested. All

the rest were cases of grave disease; and so far

as the trial, which was interrupted about the

fortieth day, extended, the patients grew worse,

or received no benefit. A case is reported on the

page before me of a soldier affected with acute

inflammation in the chest, who took successively

aconite, bryonia, nux vomica, and pulsatilla, and

after thirty-eight days of treatment remained

without any important change in his disease. The

Homoeopathic physician who treated these patients

was M. de Horatiis, who had the previous year

been announcing his wonderful cures. And M.

Esquirol asserted to the Academy of Medicine in

1835, that this M. de Horatiis, who is one of the

prominent personages in the " Examiner's "

Manifesto published in 1840, had subsequently

renounced Homoeopathy. I may remark, by the way,

that this same periodical, which is so very easy

in explaining away the results of these trials,

makes a mistake of only six years or a little

more as to the time when this at Naples was instituted.

M. Andral, the " eminent and very enlightened

allopathist " of the " Homoeopathic Examiner, " made

the following statement in March, 1835, to the

Academy of Medicine: " I have submitted this

doctrine to experiment; I can reckon at this time

from one hundred and thirty to one hundred and

forty cases, recorded with perfect fairness, in a

great hospital, under the eye of numerous

witnesses; to avoid every objection I obtained my

remedies of M. Guibourt, who keeps a Homoeopathic

pharmacy, and whose strict exactness is well

known; the regimen has been scrupulously

observed, and I obtained from the sisters

attached to the hospital a special regimen, such

as Hahnemann orders. I was told, however, some

months since, that I had not been faithful to all

the rules of the doctrine. I therefore took the

trouble to begin again; I have studied the

practice of the Parisian Homoeopathists, as I had

studied their books, and I became convinced that

they treated their patients as I had treated

mine, and I affirm that I have been as rigorously

exact in the treatment as any other person. "

And he expressly asserts the entire nullity of

the influence of all the Homoeopathic remedies

tried by him in modifying, so far as he could

observe, the progress or termination of diseases.

It deserves notice that he experimented with the

most boasted substances -- cinchona, aconite,

mercury, bryonia, belladonna. Aconite, for

instance, he says he administered in more than

forty cases of that collection of feverish

symptoms in which it exerts so much power,

according to Hahnemann, and in not one of them

did it have the slightest influence, the pulse and heat remaining as before.

These statements look pretty honest, and would

seem hard to be explained away, but it is calmly

said that he " did not know enough of the method

to select the remedies with any tolerable

precision. " [Homoeopathic Examiner, vol. i. p.

22. " Nothing is left to the caprice of the

physician. ('In a word, instead of being

dependent upon blind chance, that there is an

infallible law, guided by which the physician

must select the proper remedies.') " Ibid., in a notice of Menzel's paper.]

Who are they that practice Homoeopathy, and say

this of a man with the Materia, Medica of

Hahnemann lying before him? Who are they that

send these same globules, on which he

experimented, accompanied by a little book, into

families, whose members are thought competent to

employ them, when they deny any such capacity to

a man whose life has been passed at the bedside

of patients, the most prominent teacher in the

first Medical Faculty in the world, the

consulting physician of the King of France, and

one of the most renowned practical writers, not

merely of his nation, but of his age? I leave the

quibbles by which such persons would try to creep

out from under the crushing weight of these

conclusions to the unfortunates who suppose that

a reply is equivalent to an answer.

Dr. Baillie, one of the physicians in the great

H6tel Dieu of Paris, invited two Homoeopathic

practitioners to experiment in his wards. One of

these was Curie, now of London, whose works are

on the counters of some of our bookstores, and

probably in the hands of some of my audience.

This gentleman, whom Dr. Baillie declares to be

an enlightened man, and perfectly sincere in his

convictions, brought his own medicines from the

pharmacy which furnished Hahnemann himself, and

employed them for four or five months upon

patients in his ward, and with results equally

unsatisfactory, as appears from Dr. Baillie's

statement at a meeting of the Academy of

Medicine. And a similar experiment was permitted

by the Clinical Professor of the H6tel Dieu of

Lyons, with the same complete failure.

But these are old and prejudiced practitioners.

Very well, then take the statement of Dr. Fleury,

a most intelligent young physician, who treated

homoeopathically more than fifty patients,

suffering from diseases which it was not

dangerous to treat in this way, taking every kind

of precaution as to regimen, removal of

disturbing influences, and the state of the

atmosphere, insisted upon by the most vigorous

partisans of the doctrine, and found not the

slightest effect produced by the medicines. And

more than this, read nine of these cases, which

he has published, as I have just done, and

observe the absolute nullity of aconite,

belladonna, and bryonia, against the symptoms

over which they are pretended to exert such

palpable, such obvious, such astonishing

influences. In the view of these statements, it

is impossible not to realize the entire futility

of attempting to silence this asserted science by

the flattest and most peremptory results of

experiment. Were all the hospital physicians of

Europe and America to devote themselves, for the

requisite period, to this sole pursuit, and were

their results to be unanimous as to the total

worthlessness of the whole system in practice,

this slippery delusion would slide through their

fingers without the slightest discomposure, when,

as they supposed, they had crushed every joint in

its tortuous and trailing body.

----------

3. 1 have said, that to show the truth of the

Homoeopathic doctrine, as announced by Hahnemann,

it would be necessary to show, in the third

place, that remedies never cure diseases when

they are not capable of producing similar

symptoms. The burden of this somewhat

comprehensive demonstration lying entirely upon

the advocates of this doctrine, it may be left to their mature reflections.

It entered into my original plan to treat of the

doctrine relating to Psora, or itch -- an almost

insane conception, which I am glad to get rid of,

for this is a subject one does not care to handle

without gloves. I am saved this trouble, however,

by finding that many of the disciples of

Hahnemann, those disciples the very gospel of

whose faith stands upon his word, make very light

of his authority on this point, although he

himself says, " it has cost me twelve years of

study and research to trace out the source of

this incredible number of chronic affections, to

discover this great truth, which remained

concealed from all my predecessors and

contemporaries, to establish the basis of its

demonstration, and find out, at the same time,

the curative medicines that were fit to combat

this hydra in all its different forms.

But, in the face of all this, the following

remarks are made by Wolff, of Dresden, whose

essays, according to the editor of the

" Homoeopathic Examiner, " " represent the opinions

of a large majority of Hornoeopathists in Europe. "

" It cannot be unknown to any one at all familiar

with Homoeopathic literature, that Hahnemann's

idea of tracing the large majority of chronic

diseases to actual itch has met with the greatest

opposition from Homoeopathic physicians

themselves. " And again, " If the Psoric theory has

led to no proper schism, the reason is to be

found in the fact that it is almost without any influence in practice. "

We are told by Jahr, that Dr. Griesselich,

" Surgeon to the Grand Duke of Baden, " and a

" distinguished " Homoeopathist, actually asked

Hahnemann for the proof that chronic diseases,

such as dropsy, for instance, never arise from

any other cause than itch; and that, according to

common report, the venerable sage was highly

incensed (forct courroucé) with Dr. Hartmann, of

Leipsic, another " distinguished " Homoeopathist,

for maintaining that they certainly did arise from other causes.

And Dr. Fielitz, in the " Homoeopathic: Gazette "

of Leipsic, after saying, in a good-natured way,

that Psora is the Devil in medicine, and that

physicians are divided on this point into

diabolists and exorcists, declares that,

according to a remark of Hahnemann, the whole

civilized world is affected with Psora. I must

therefore disappoint any advocate of Hahnemann

who may honor me with his presence, by not

attacking a doctrine on which some of the

disciples of his creed would be very happy to

have its adversaries waste their time and

strength. I will not meddle with this

excrescence, which, though often used in time of

peace, would be dropped, like the limb of a

shell-fish, the moment it was assailed; time is

too precious, and the harvest of living

extravagances nods too heavily to my sickle, that

I should blunt it upon straw and stubble

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Do you find any difference between these two articles?

Ignacio

Ignacio Fojgel,M.D.

Buenos Aires, Argentina.

The British Homeopathic Association

The Lancet article is fundamentally flawed

07-09-2005, 3:02 pm

The article published on homeopathy in the Lancet recently has fundamental

flaws, writes Mathie, Research Development Adviser of the BHA and

Faculty of Homeopathy.

What the paper studied:

The authors analysed placebo-controlled trials of homeopathy and

conventional medicine (matched for disorder and type of clinical outcome)

published up to January 2003 (1). 110 homeopathy trials and 110 matched

trials in conventional medicine were included; they were not necessarily

peer-reviewed papers. They were assessed using standard criteria of trial

quality (randomisation, masking, data analysis methods) and by treatment

effect using odds ratios (an odds ratio of less than 1.0 indicating an

effect greater than placebo). The original studies included a wide range

of medical conditions; nearly half the studies comprised research in

respiratory tract infections, pollinosis & asthma, and gynaecology &

obstetrics. The homeopathy trials concerned all forms of the therapy,

including classical (individualised) homeopathy, ‘clinical homeopathy’,

complex homeopathy, or isopathy. The majority of conventional medicine

trials investigated specific pharmaceutical drugs (non-steroidal,

anti-allergic, virostatic, or antibiotic). Treatment approach in each

category of trial was either therapeutic or prophylactic.

What the paper shows:

Viewing the results of the trials overall, there is a broadly similar

positive treatment effect in both homeopathy and conventional medicine. In

both categories of trial, those with fewer patients typically showed more

positive treatment effects than larger trials. This is shown in the

paper’s Figure 2, where trials with the largest standard error tend to

have the lowest odds ratio. The authors do not quote mean odds ratios for

the two groups of trials. 21 homeopathy trials and 9 in conventional

medicine were judged to be of ‘higher quality’. The author’s key analysis

was then restricted to the ‘larger’ 14 of those trials (8 homeopathy and 6

conventional medicine; none of them cited specifically); this analysis

resulted in a mean odds ratio of 0.88 for homeopathy trials and 0.58 for

conventional medicine trials. There was thus no longer a convincing

positive treatment effect of homeopathy as compared with that of

conventional medicine. The paper’s main conclusion is that the clinical

effects of homeopathy are probably those of placebo.

What the Lancet editor says:

Under the headline ‘The end of homoeopathy’, the journal editorial states

‘Now doctors need to be bold and honest with their patients about

homoeopathy’s lack of benefit, and with themselves about the failings of

modern medicine to address patients’ needs for personalised care’. It adds

the comment ‘Surely the time has passed for selective analyses, biased

reports, or further investment in research to perpetuate the homoeopathy

versus allopathy debate’.

Our commentary on this publication:

As the following paragraphs illustrate, the paper has not demonstrated

homeopathy’s lack of benefit. Regrettably, in publishing and commenting on

this paper, the journal has displayed some of these unwelcome attributes

of selective analysis and biased reporting. And investment in clinical

research in homeopathy needs to be enhanced, not withheld.

There are a number of concerns in the way the paper approaches homeopathy

trials: for example, its criteria of study quality do not reflect the

homeopathic relevance of the clinical outcome/s measured; in addition,

placebo-controlled design was probably not appropriate in the trials of

individualised homeopathy (2). In other words, standard assessment

criteria are insufficient to gauge ‘high quality’ in homeopathy trials.

Another fundamental concern is that the paper gives no clue about the

nature of the 14 trials selected for the key analysis: whether they were

mainly therapeutic or prophylactic, for example, and whether the

homeopathic interventions were classical, ‘clinical’ or complex

homeopathy, or isopathy. Knowledge of these would potentially make a great

difference to the inferences that should be drawn. Given the heterogeneity

of homeopathy trials, it seems unlikely that the design and methods of

just 8 can be representative of 110. Nor are we offered proper summary

data on the odds ratios for effectiveness in the two sets of 110 trials

overall; without such information, it is impossible to gauge the impact of

having narrowed the analysis to just 8+6 trials.

There are other bizarre features of this paper. On reading its text, it

seems that only the literature between 1995 and January 2003 was included

in the analysis. This would have built on a previous major meta-analysis

of homeopathy trials (3). However, on examination of the web-table that

lists all the references, it becomes apparent that 62 of the papers

analysed were actually published before 1995. The remaining papers

analysed were published from that year onwards, but some of the main

articles during that time have not been included. Inexplicably too, a

substantial number of the papers reviewed in the previous meta-analysis

are absent from the new one.

The wider view:

Most independent scientific observers would regard this analysis as

inconclusive in its results and opaque in some of its key methods and

reporting. And it has the limitations of any analysis of clinical research

in homeopathy that attempts to group together all homeopathic conventions

of treatment and all medical conditions that have been investigated. A

comprehensive analysis of that type can merely make overall conclusions

and may miss specific areas of therapeutic importance – the authors

themselves highlight (but dismiss) the fact that 8 trials of homeopathy in

upper respiratory tract infections have strongly positive findings

overall. It is for this very reason that we adopted an analysis of the

homeopathic research literature that focused instead on individual

clinical trials and their findings (reference 10 in ‘Research in

Homeopathy’ section of this website) (4).

The way forward:

We certainly agree with the Lancet paper’s authors that ‘future research

efforts should focus on … the place of homeopathy in health-care systems’

and about ‘the failings of modern medicine’. That should mean

concentrating more on conducting trials that compare homeopathy properly

and fairly with standard medical care. There remains a place for

placebo-controlled trials, but these have to be considered with insight

and wisdom. These and other trial design issues in homeopathy should be

properly informed by prior clinical observational research and

well-conceived pilot trials. The Lancet publication has done nothing to

inform this important field of research in the constructive or careful

manner that it deserves.On Sat, 29 Oct 2005 13:03:40 -0300, Steve

Culpepper <steve@...> wrote:

> At 11:43 AM 10/29/2005 -0400, you wrote:

>> At 08:07 AM 10/29/2005 -0700, you wrote:

>> >Thought this would help add to the homeopathy thread.

>> >Perhaps we're influence too much by " main stream media "

>

> A short interesting quote from

> http://blogs.salon.com/0001561/2005/08/27.html#a8063

>

> The medical journal The Lancet is effectively saying it's about time

> telling the truth about homeopathy to patients: The jury is in.

>

<http://today.reuters.com/News/newsArticle.aspx?type=healthNews & storyID=2005-08-\

26T144857Z_01_EIC653236_RTRIDST_0_HEALTH-HOMEOPATHY-PLACEBO-DC.XML>Homeopathy

> doesn't work better than sugary pills.

>

> In the current article, Dr. Matthias Egger, from the University of

> Berne in Switzerland, and associates searched 19 electronic databases

> covering the period from 1995 to 2003 to identify scientific trials

> of homeopathy, and matched them with trials in conventional medicine.

>

> The team identified 110 trials each of homeopathy and conventional

> medicine, or allopathy. They used sophisticated statistical analysis

> to score the results of the studies, with those below 1.0 indicating

> a beneficial effect of treatment versus inactive placebo.

>

> Including the largest trials, which were considered the most

> reliable, the overall scores were 0.96 for homeopathy and 0.67 for

> conventional medicine.

>

> Egger and his colleagues say the results provide " no convincing

> evidence that homeopathy was superior to placebo, whereas for

> conventional medicine an important effect remained. "

>

> The Lancet editors weigh in on this topic, saying, " Surely the time

> has passed for selective analyses, biased reports, or further

> investment in research to perpetuate the homeopathy versus allopathy

> debate. "

>

> They add: " Now doctors need to be bold and honest with their patients

> about homeopathy's lack of benefit, and with themselves about the

> failings of modern medicine to address patients' needs for personalized

> care. "

>

> Now, you may be tempted to say this is bad news for homeopaths. Not

> at all! First, and obviously, their typical patients are too ignorant

> and too desperate to care that the evidence is solidly against

> homeopathy. But there are many reasons this is actually good news for

> homeopathy, as well as for the rest of us.

>

> Homeopaths

> * do not have to go through the very lengthy and expensive

> process of having their drugs tested and approved.

> * do not risk being

> <http://news.bbc.co.uk/1/hi/business/4189354.stm>sued out of $253

> million if someone dies after taking their drug (no effect means no

> bad effects, either!)

> * don't have to pay for expensive malpractice insurance

> * don't have to explain how water " remembers " the right molecules

> to cure your disease, but forgets everything else the same water has

> been in touch with since the dawn of time

> * don't have to learn anything about the real world, which would

> require, you know, an education

> * don't have to worry about alt.med'ers condemning them for being

> greedy " pharma shrills "

> * can continue making money on ignorance, which is never in short

> supply

>

> We

> * don't have to throw out everything science knows about physics

> and chemistry, as we would have to do if homeopathy was true

> * don't have to waste even more money researching this nutty idea

> * don't need to visit a homeopath

> * may find the lines shorter at the medical doctor thanks to all

> those patients visiting a homeopath

>

> A win-win situation if I ever saw one.

>

>

>

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