Re: Aricept Losing Efficacy (was: Re: Loss of weight) and OT

March 8, 2007

, I didn't read who this was from, until the very end. I thought

wrote it.

Mercy! You smart people.

Imogene

In a message dated 3/8/2007 4:51:37 AM Central Standard Time,

octoryrose@... writes:

<snip>Unfortunately, the two drugs you mention (Alzhemed and the R-

Flurbiprofen) probably won't do much in Lewy - they're targeted to

destroy beta-amyloid rather than the alpha-synuclein that is the big

problem in Lewy. The subgroup that they may be helpful for is the

group of AD patients with overlaid DLB, and vice versa, but you've

gotta have impairment caused by beta-amyloid to get either of those to

work. Sorry to be a buzzkill.<snip>

Yeah... from what I read about Alzhemed & Flurizan, I understood it as

that too... Just new meds that would benefit those with AD... but what

I did find interesting in that post is their comment: " During the next

five years, we forecast that currently-available therapies will expand

their labels to include other forms of dementia, ... "

Which is what Exelon did... expanded their label to include PDD...

which in a way is good news for LBD b/c more research re: LBD vs. just

Alz. may be taking place...

<snip>The good news is that there are similar efforts to find ways to

keep alpah-synuclein from aggregating to form Lewy bodies, and to

destroy the bodies that have already formed.<snip>

Yes... read something regards to this thought too:

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