Re: Re: Enbrel vs. any other biologic

[Guest guest]

My daughter is on Prednisone, Kineret & Cyclosporine for her primary

condition...All have worked well together to help her. Enbrel did not help

much...She used it many years ago.

Take good care....

Re: Enbrel vs. any other biologic

Has anyone out there had Enbrel stop working for them? If so what biologic

worked for you after Enbrel?

I was on Enbrel for six years and it put me in remission for all that time

but did finallty stop working last fall. I've been taking Humira now for

six weeks and it does seem to be working. Not perfect but most of my morning

pain and stiffness is gone. Aleeta

--

mareed561@...

[Guest guest]

I have been on enbrel 50 mg for ~8 years and am noting more flares recently..i

am having troubles with pneumonia, shingles..ouch...and corneal ulcers ...not

knowing if I can handle much more....don't know whether to blame it on the

stills disease or the meds...hoping for a cure for us all...

>Has anyone out there had Enbrel stop working for them? If so what biologic

>worked for you after Enbrel?

>

>I was on Enbrel for six years and it put me in remission for all that time

>but did finallty stop working last fall. I've been taking Humira now for

>six weeks and it does seem to be working. Not perfect but most of my morning

>pain and stiffness is gone. Aleeta

>

>--

>mareed561@...

>

>

>

[Guest guest]

I have been on enbrel 50 mg for ~8 years and am noting more flares recently..i

am having troubles with pneumonia, shingles..ouch...and corneal ulcers ...not

knowing if I can handle much more....don't know whether to blame it on the

stills disease or the meds...hoping for a cure for us all...

>Has anyone out there had Enbrel stop working for them? If so what biologic

>worked for you after Enbrel?

>

>I was on Enbrel for six years and it put me in remission for all that time

>but did finallty stop working last fall. I've been taking Humira now for

>six weeks and it does seem to be working. Not perfect but most of my morning

>pain and stiffness is gone. Aleeta

>

>--

>mareed561@...

>

>

>

[Guest guest]

S.

 

aw a cure for us all now that would be nice and then the next step would be to

clone any parts any of us have lost because of it also. Hey if your going to

wish wish big I say.

 Now about what your noticing with embrel. I do hope you have been talking to

your RA doc about it and if not If I was in your shoes I think I would be as

maybe as has been with other it may not be working as it used to and the time

has come to change things up a bit. I dread the day that MTX stops working for

me as one its cheap and two its cheap LOL I know I was approved for Embrel years

ago but that was at the time of my divorce and when y ex stopped or I should say

removed me from her health insurance way before it even went to court so with

out any medical coverage I did not get the chance to try it . My doc I have now

wanted me to try Keneckt (spelling) but we could not find away to afford it also

as my out of pocket cost was more then my SSDI monthly check but as long as MTX

seams to be doing the trick that were I am at but ya if things are not working

like they used to as I said it may be time to mix it up a bit but any way no

mater what wishing

you the best

 

Hugs

 

 

The  Redneck  

Marty G     

 

Subject: Re: Re: Enbrel vs. any other biologic

 

I have been on enbrel 50 mg for ~8 years and am noting more flares recently..i

am having troubles with pneumonia, shingles..ouch...and corneal ulcers ...not

knowing if I can handle much more....don't know whether to blame it on the

stills disease or the meds...hoping for a cure for us all...

[Guest guest]

Remaining on the same topic; I had been on Actemra for 15 months following

failures on Humira and Kineret. For almost one year I had near complete relief

of the sudden attacks of painful episodes and almost normalization of my ability

to perform basic activities. It was as if my life had stabilized and I could

expect one reasonable day after another without that sudden back to the

beginning flare-up. About the 14th month the Actemra stopped working and every

symptom came back even shaking chills; all in the absence of any changes in my

lab work. After the 15th infusion and another month with essentially no change,

my rheumatologist suggested dropping the Actemra and adding Rituxan; otherwise I

take Celebrex one to two per day. My Rheumatologist explained that in his

experience with patients with abnormal immune systems after a period of time a

biologic medication will lose its effectiveness. He further explained it is

possible that our immune systems can rebalance back to their abnormal state by

counter-acting the very biologic mechanism that allows the medication to exert

its effects.

I received my first infusion of Rituxan two weeks ago. During the infusion the

possible allergic the effects of the Rituxan are balanced by Benadryl and

steroid infusions. Besides some itching and tightening in my throat the infusion

though lengthy was uneventful. It takes about two weeks for the Rituxan to

reduce your B-cell lymphocytes and begin exerting some benefit. I have been very

careful to avoid exposures to possible sources of viral or bacterial illness but

other than that I have been trying to lead life as usual. So far I have felt

better than the last two months of Actemra and I continue to hope for additional

gains in my health and activity level. I receive another infusion this coming

Tuesday and the next infusion is 4 to 6 months later. I will provide more

information as time progresses.

Thanks,

Harry S.

To: stillsdisease

From: karensongy2001@...

Date: Sat, 21 May 2011 14:37:23 -0700

Subject: Re: Re: Enbrel vs. any other biologic

I have been on enbrel 50 mg for ~8 years and am noting more flares

recently..i am having troubles with pneumonia, shingles..ouch...and corneal

ulcers ...not knowing if I can handle much more....don't know whether to blame

it on the stills disease or the meds...hoping for a cure for us all...

>Has anyone out there had Enbrel stop working for them? If so what biologic

>worked for you after Enbrel?

>

>I was on Enbrel for six years and it put me in remission for all that time

>but did finallty stop working last fall. I've been taking Humira now for

>six weeks and it does seem to be working. Not perfect but most of my morning

>pain and stiffness is gone. Aleeta

>

>--

>mareed561@...

>

>

>