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Re: Digest Number 1773

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Hi, Dale,

>>2) RNase L digests double-stranded RNAs (like some viral chromosomes),

while

>>mRNA is single-stranded

>>So even high levels of RNase L should not degrade enough mRNA to make

any

>>difference.

>

>Does this mean that RNase L is an effective defense against the spread

of

>viruses between cells but not a defense against viruses that are already

>inside cells?

It s a bit more complicated than that. RNase L is acting in concert with NK

cells, cytotoxic T cells, and the complement system, all of which can kill

virus-infected cells. When these cells are killed, their contents get dumped

into the bloodstream.

If nothing cleaned it up, these contents would get taken up by other cells.

This includes the dsRNA viral chromosomes and replication intermediates. If

that happened, the cell taking it up would become infected even though it

was never attacked by an intact virus. The RNase L mops up the dsRNA int he

bloodstream to keep this from happening.

Intact virus particles, which are covered with a lipid bilayer membrane

(pretty much the same as a cell membrane) and proteins, do not have their

dsRNA exposed, so it is not available to be degraded by RNase L. But in a

lot of active viral infections there are more infections from the

replicating intermediates than by intact virus. So the RNase L does serve an

important purpose.

Jerry

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Jerry,

That was an incredibly understandable explanation. Thank you.

-Dale

At 03:52 PM 4/22/01 -0400, Jerry wrote:

>Hi, Dale,

>

>>>2) RNase L digests double-stranded RNAs (like some viral chromosomes),

>while

>>>mRNA is single-stranded

>>>So even high levels of RNase L should not degrade enough mRNA to make

>any

>>>difference.

>>

>>Does this mean that RNase L is an effective defense against the spread

>of

>>viruses between cells but not a defense against viruses that are already

>>inside cells?

>

>It s a bit more complicated than that. RNase L is acting in concert with NK

>cells, cytotoxic T cells, and the complement system, all of which can kill

>virus-infected cells. When these cells are killed, their contents get dumped

>into the bloodstream.

>

>If nothing cleaned it up, these contents would get taken up by other cells.

>This includes the dsRNA viral chromosomes and replication intermediates. If

>that happened, the cell taking it up would become infected even though it

>was never attacked by an intact virus. The RNase L mops up the dsRNA int he

>bloodstream to keep this from happening.

>

>Intact virus particles, which are covered with a lipid bilayer membrane

>(pretty much the same as a cell membrane) and proteins, do not have their

>dsRNA exposed, so it is not available to be degraded by RNase L. But in a

>lot of active viral infections there are more infections from the

>replicating intermediates than by intact virus. So the RNase L does serve an

>important purpose.

>

>Jerry

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  • 7 months later...

In a message dated 12/5/2001 10:11:35 AM Eastern Standard Time,

writes:

> Does DMSA pull out essential elements or just toxic ones? My doctor said

> >that DMSA if very specific and would pull out my lead and mercury without

> >pulling out essential elements. Is this the concensus of this group or do

> I

> >need to be taking some minerals between chelations?

> >Thanks,

> >Pattie in GA

>

> Andy thinks it DOESN'T pull out essential elements.

> I don't know if there is any consensus about this on this list,

> or anywhere else. I think there are mixed opinions, and varying

> practices about it.

>

> You may need to supplement minerals *anyway* == mercury toxic

> people are often nutritional off balance.

>

> Moria

Very good point, Moria. Thanks.

Pattie in GA

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  • 1 year later...
Guest guest

Elaine,

There is a camp near Atlanta called Camp Sparrowwood that is an off

shoot of Camp Calvin which I have heard good things about. I took

to a Girl Scout Camp in North Carolina yesterday for the

week. They have been great and were not the least bit concerned about

her " abilities " . They did talk to me about her communication book and

signing (She is non-verbal). When I talked about how she can

be " stubborn or ignore " you, they said yes just like any other

child!! She loves to go and they seemed to love to have her. As she

is getting older though I will need to look into others places.

Hope it helps. Kathy

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  • 7 months later...

, the pumpkin seed dip sounds yummy. The only possible avoid for nonnies

would be in the chicken stock, assuming it's store bought instead of homemade.

I have yet to find a store bought stock of any kind that's avoid-free for

nonnies. I've found that usually substituting water is okay instead of stock,

so I might try it that way.

Jill, since nonnies often react very strongly to eating avoids and have

additional health challenges as a result, I would say that if one *is* a

nonnie, it's drastic. I'm glad I made the shift incrementally, and I'm *very

glad* I found out I'm a nonnie. The somewhat subtle shifts (that feel big at

first) are making a big difference in my health and well-being. I found that I

was able to lose quite a bit of weight (approx 30lbs on the O secretor plan)

but the next 40 have been MUCH easier to lose on the nonnie plan.

Kate, great list of what to use with nut butters and dips. Or, in my case, I

just eat the almond butter by the spoonful. Definitely my indulgence of the

moment. Also, wouldn't sweet potato chips be cool? Anyone have any success with

creating a crunchy sweet potato chip? DANG, that sounds good! :-)

ita

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ita,

Use ghee made from butter and slice your sweet potato very thin. Salt if you

want and bake. You have sweet potato chips.

Re: Digest Number 1773

> , the pumpkin seed dip sounds yummy. The only possible avoid for

nonnies

> would be in the chicken stock, assuming it's store bought instead of

homemade.

> I have yet to find a store bought stock of any kind that's avoid-free for

> nonnies. I've found that usually substituting water is okay instead of

stock,

> so I might try it that way.

>

> Jill, since nonnies often react very strongly to eating avoids and have

> additional health challenges as a result, I would say that if one *is* a

> nonnie, it's drastic. I'm glad I made the shift incrementally, and I'm

*very

> glad* I found out I'm a nonnie. The somewhat subtle shifts (that feel big

at

> first) are making a big difference in my health and well-being. I found

that I

> was able to lose quite a bit of weight (approx 30lbs on the O secretor

plan)

> but the next 40 have been MUCH easier to lose on the nonnie plan.

>

> Kate, great list of what to use with nut butters and dips. Or, in my case,

I

> just eat the almond butter by the spoonful. Definitely my indulgence of

the

> moment. Also, wouldn't sweet potato chips be cool? Anyone have any success

with

> creating a crunchy sweet potato chip? DANG, that sounds good! :-)

>

> ita

>

>

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> Kate, great list of what to use with nut butters and dips. Or,

in my case, I

> just eat the almond butter by the spoonful. Definitely my

indulgence of the

> moment. Also, wouldn't sweet potato chips be cool? Anyone have

any success with

> creating a crunchy sweet potato chip? DANG, that sounds good!

:-)

>

> ita

I've found sweet potato chips in the store but I don't know if

they contain any avoids for nonnies.

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  • 1 year later...
Guest guest

Grace

As I written here many times over the past few years, flaxseed oil should

never be taken without thoroughly mixing it into lowfat cultured dairy like

cottage cheese or yoghurt. See the work of Johanna Budwig, another expert on

fats,

or join the flaxseedoil2 group and read the FILES section.

Flaxseed oil and chemo therapy are not a good combination.

Please remember that in addition to seizures, Charlie has been also dealing

with agressive bladder cancer since last April.

Hope you are well

mjh

> Message: 3

> Date: Mon, 28 Feb 2005 08:41:10 -0800 (PST)

> From: Grace <foxyfoxgrace@...>

> Subject: Re: MJH

>

> Marilyn,

>

> I was planning on starting on the flaxseed oil, why did you

> discontinue giving it to Charlie?

>

> Grace

>

> foxhillers@... wrote:

> In a message dated 2/28/05 6:45:33 AM Eastern Standard Time,

> writes:

>

> >Ten days ago I started dosing him in earnest with a vit B complex

> >[thanks Arnold!], taurine and cod liver oil + calcium supplement as

> >well as removing all gluten and neurotransmitters from his diet and

> >really trying to boost his vits and enzymes naturally with good

> >quality meat,veg ,seeds etc. rather than extra supplements.

> >

>

> .

> .>>> Neurotransmitters are critically important. I think what you may mean

> is that you have diminished the excitory stuff (see Blaylock's book on

> Excitoxins) in his diet.

>

> My son, Charlie's been on the supplements plus others like 9 grams of fish

> oil a day for several years and it has made a significant difference in the

> quality of his life. Fish oil contains EPA and DHA, important brain fats. He

> also

> get coconut oil, another healthy brain fat. Flaxseed oil was discontinued

> at

> hospitalization in Sept 2004.

>

> For years he was on Depakote and Lamictal polytherapy. Since late

> September's cancer surgery, he is on Depakote monotherapy.

>

> Since birth to age 21, he was on Phenobarbital and Dilantin.

>

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Guest guest

MJH, Does fish oil have to be mixed into a lowfat cultered dairy too

like flax oil?

> > In a message dated 2/28/05 6:45:33 AM Eastern Standard Time,

> > writes:

> >

> > >Ten days ago I started dosing him in earnest with a vit B complex

> > >[thanks Arnold!], taurine and cod liver oil + calcium supplement as

> > >well as removing all gluten and neurotransmitters from his diet and

> > >really trying to boost his vits and enzymes naturally with good

> > >quality meat,veg ,seeds etc. rather than extra supplements.

> > >

> >

> > .

> > .>>> Neurotransmitters are critically important. I think what you

may mean

> > is that you have diminished the excitory stuff (see Blaylock's

book on

> > Excitoxins) in his diet.

> >

> > My son, Charlie's been on the supplements plus others like 9 grams

of fish

> > oil a day for several years and it has made a significant

difference in the

> > quality of his life. Fish oil contains EPA and DHA, important

brain fats. He

> > also

> > get coconut oil, another healthy brain fat. Flaxseed oil was

discontinued

> > at

> > hospitalization in Sept 2004.

> >

> > For years he was on Depakote and Lamictal polytherapy. Since late

> > September's cancer surgery, he is on Depakote monotherapy.

> >

> > Since birth to age 21, he was on Phenobarbital and Dilantin.

> >

>

>

>

>

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Guest guest

Marilyn,

I still remember your posts about the flaxseed being mixed with the yoghurt or

cottage cheese, I was just wondering why you had stopped. Thanks!

Grace

foxhillers@... wrote:

Grace

As I written here many times over the past few years, flaxseed oil should

never be taken without thoroughly mixing it into lowfat cultured dairy like

cottage cheese or yoghurt. See the work of Johanna Budwig, another expert on

fats,

or join the flaxseedoil2 group and read the FILES section.

Flaxseed oil and chemo therapy are not a good combination.

Please remember that in addition to seizures, Charlie has been also dealing

with agressive bladder cancer since last April.

Hope you are well

mjh

> Message: 3

> Date: Mon, 28 Feb 2005 08:41:10 -0800 (PST)

> From: Grace <foxyfoxgrace@...>

> Subject: Re: MJH

>

> Marilyn,

>

> I was planning on starting on the flaxseed oil, why did you

> discontinue giving it to Charlie?

>

> Grace

>

> foxhillers@... wrote:

> In a message dated 2/28/05 6:45:33 AM Eastern Standard Time,

> writes:

>

> >Ten days ago I started dosing him in earnest with a vit B complex

> >[thanks Arnold!], taurine and cod liver oil + calcium supplement as

> >well as removing all gluten and neurotransmitters from his diet and

> >really trying to boost his vits and enzymes naturally with good

> >quality meat,veg ,seeds etc. rather than extra supplements.

> >

>

> .

> .>>> Neurotransmitters are critically important. I think what you may mean

> is that you have diminished the excitory stuff (see Blaylock's book on

> Excitoxins) in his diet.

>

> My son, Charlie's been on the supplements plus others like 9 grams of fish

> oil a day for several years and it has made a significant difference in the

> quality of his life. Fish oil contains EPA and DHA, important brain fats. He

> also

> get coconut oil, another healthy brain fat. Flaxseed oil was discontinued

> at

> hospitalization in Sept 2004.

>

> For years he was on Depakote and Lamictal polytherapy. Since late

> September's cancer surgery, he is on Depakote monotherapy.

>

> Since birth to age 21, he was on Phenobarbital and Dilantin.

>

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  • 9 months later...

howdy, I have a question for the group. I am getting

my naltrexone 3mg capsules with lactose filler, which

I know is preferred. however I am allergic to dairy.

so I stay away from dairy. I called my pharmacist and

he said he could put rice flour as the filler. Is this

o.k. I know I am not allergic to rice. I told him no

corn starch or calcium carbonate. I asked him for

acidophilous or avicel. he said lets try rice first.

I know the amount of lactose is probably so small, but

I do get a little cramping and slight stomach ache

now. What do you think? Thanks

keith

--- low dose naltrexone wrote:

>

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I would tell him no on the rice. Does it contain gluten? Skip is the

compounder who has more experience than anyone I'm aware of and he uses

avicel. I think that is thesafest way to go. It is such a small thing yet

can make a huge difference for you. Make sure your pharmacist complies with

your wishes. Have him call Skip if he has any doubts. Best Wishes, Kathy

Re: [low dose naltrexone] Digest Number 1773

> howdy, I have a question for the group. I am getting

> my naltrexone 3mg capsules with lactose filler, which

> I know is preferred. however I am allergic to dairy.

> so I stay away from dairy. I called my pharmacist and

> he said he could put rice flour as the filler. Is this

> o.k. I know I am not allergic to rice. I told him no

> corn starch or calcium carbonate. I asked him for

> acidophilous or avicel. he said lets try rice first.

> I know the amount of lactose is probably so small, but

> I do get a little cramping and slight stomach ache

> now. What do you think? Thanks

> keith

>

> --- low dose naltrexone wrote:

>

>>

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