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Pamelor

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Dear Jolene,

You said:

<<Has anyone taken pamelor? If so, what side effects did you have?>>

** The adverse effects for all antidepressants are many and virtually

the same. Below is a list that the drug companyt will admit to. You can be

assured there are more that they have not been required to list.

PAMELOR (nortriptyline)

Included in the following list are a few adverse reactions that have not

been reported with this specific drug. However, the pharmacologic

similarities among the tricyclic antidepressant drugs require that each of

these reactions be considered when nortriptyline is administered.

Cardiovascular:

Hypotension, hypertension, tachycardia, palpitation, myocardial infarction,

arrhythmias, heart block, stroke.

Psychiatric:

Confusional states (especially in the elderly) with hallucinations,

disorientation, delusions; anxiety, restlessness, agitation; insomnia,

panic, nightmares; hypomania; exacerbation of psychosis.

Neurologic:

Numbness, tingling, paresthesias of extremities; incoordination, ataxia,

tremors; peripheral neuropathy, extrapyramidal symptoms; seizures,

alteration of EEG patterns; tinnitus.

Anticholinergic:

Dry mouth and, rarely, associated sublingual adenitis or gingivitis; blurred

vision, disturbance of accommodation, mydriasis; constipation, paralytic

ileus; urinary retention, delayed micturition, dilation of the urinary

tract.

Allergic:

Skin rash, petechiae, urticaria, itching, photosensitization (avoid

excessive exposure to sunlight); edema (general or of face and tongue), drug

fever, cross-sensitivity with other tricyclic drugs.

Hematologic:

Bone-marrow depression, including agranulocytosis, aplastic anemia;

eosinophilia; purpura; thrombocytopenia.

Gastrointestinal:

Nausea and vomiting, anorexia, epigastric distress, diarrhea; peculiar

taste, stomatitis, abdominal cramps, black tongue, constipation, paralytic

ileus.

Endocrine; gynecomastia in the male; breast enlargement and galactorrhea in

the female; increased or decreased libido, impotence; testicular swelling;

elevation or depression of blood sugar levels; syndrome of inappropriate ADH

(antidiuretic hormone) secretion.

Other:

Jaundice (simulating obstructive); altered liver function, hepatitis, and

liver necrosis; weight gain or loss; perspiration; flushing; urinary

frequency, nocturia; drowsiness, dizziness, weakness, fatigue; headache;

parotid swelling; alopecia.

Regards,

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