Measurement of endorphins

[Guest guest]

This is an excerpt from a radio interview with Dr. Bihari in 2003,

discussing the measurement of endorphins during his early experiments

with LDN for his AIS patients:

Dr. Bihari: " ....When I discovered that people with HIV had less than

twenty percent of the normal levels of endorphins, that meant that the

virus not only kills the immune system cells, it also weakens the

whole immune system, so that it's not as able to fight the virus.

We began looking for ways to use naltrexone to raise endorphins

without blocking them. We hired a laboratory scientist to measure

endorphin levels. We'd measure in the afternoon, then we'd give the

first dose at bedtime that night. Then we'd measure again at the same

time the next day; then again at one week, and again at one month.

We found that doses in the range of 1.75 to 4.5 milligrams (which is

just a fraction of the recommended dosage to addicts) would trigger or

jumpstart endorphin production during the night.

Except with exercise, endorphins are made only between two and four in

the morning. The brain sends a message out to the adrenal and

pituitary glands and tells them to make endorphins. Giving a dose

three, four, five hours before that, at bedtime, is enough to make

that message from the brain much stronger. "

Dr. Kokayi: " Were you able to document that the levels of endorphins

were then actually raised? "

Dr. Bihari: " The level of endorphins went up by two hundred to three

hundred percent. We then started a little foundation and did a

placebo-controlled trial in which half the patients got naltrexone and

half got sugar pills. A year later when we broke the code, we

discovered that people with HIV who took LDN had only an eight

percent mortality rate in the year, while people who were on the

placebo had a thirty-three percent mortality rate. And of course they

had many more infections and their immune systems declined. That was

a startling discovery.... "

You can read the rest of this interview at http://www.gazorpa.com.

Hope this helps...

Gazorpa