Works on the circulatory system and Co Q10

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WHAT CO-Q-10 IS GOOD FOR

Co-Q-10 plays a crucial role in the generation of cellular energy, is

a significant immunologic stimulant, increases circulation, has anti-

aging effects, and is beneficial for the cardiovascular system. It is

of great interest to researchers studying heart disease, aging,

cancer, obesity, athletic performance, and other problems associated

with the deficiency of this coenzyme in the body.

Some key scientific research findings have documented the role of Co-

Q-10 in:

* Protecting Cells Against Oxidative Damage Through a Powerful

Antioxidant Action * Generating Energy and Endurance by Rejuvenating

Cellular Mitochondria * Stimulating Production of Healthy Gum Tissue

to Combat Periodontal Disease * Controlling Hypertension and Blood

Pressure Disorders * Reducing Damage Due to Hypoxic Injury (Tissue

Damage By a Lack of Oxygen) * Fortifying the Body Against Effects of

Some Cancer Treatments * Nutritional Support for Improved Immune

Response * Balancing Metabolic System Involved in Weight Management

As we age, our bodies lose their ability to synthesize sufficient

amounts of Co-Q-10 from our daily dietary intake. Thousands of

scientific studies have proven that Co-Q-10 is essential for ensuring

a healthy immune system, cardiovascular health and many other vital

body functions. While the medical experts have understood the

importance of this exciting nutrient for years, commercial production

of Co-Q-10 was not available until 1977. The ability for Co-Q-10 to

preserve and repair cellular integrity, while supporting energy

production within the human body, makes it one of the most important

nutrients ever discovered!

Besides working miracles for heart patients, Co-Q-10 has been used

successfully to treat gum disease, revitalize muscles of muscular

dystrophy victims, lowers blood pressure and bolsters the immune

system, possibly even preventing cancer. Dr. Langsjoen of

& White Memorial Hospital in Texas, reports: " patients, steadily

worsening and expected to die within two years under conventional

therapy, generally showed an extraordinary clinical improvement,

indicating that Co-Q-10 therapy might extend the lives of such

patients. "

" Co-Q-10 is involved in energy conversion in the body, " explains Dr.

Frederick Crane, a biochemist from Purdue University. " With low

levels of the substance, muscles won't function properly, nerve

impulses from the brain slow down, the activity of all body organs

slow down. "

A six year study of severely ill heart patients showed that 75% of Co-

Q-10 recipients survived for three years or more with major problems

of congestive heart failure while only 25% of similar patients

survived without it. " This is really a very important enzyme to the

body, " Dr. Crane said, " It's very useful, very exciting, and we still

don't know all the possible uses. "

CARDIOVASCULAR DISEASE

* Hypertension (High Blood Pressure) * Angina Pectoris * Congestive

Heart Failure * Mitral Valve Prolapse

Coenzyme Q10 is an essential component of the metabolic processes

involved in energy production. Individuals with a form of

cardiovascular disease often are deficient in Co-Q-10 and require

increased tissue levels of Co-Q-10. Clinical studies have indicated

that Co-Q-10 is of considerable benefit in the treatment of

hypertension and other problems associated with the cardiovascular

system.

Co-Q-10 deficiency is common in individuals with heart disease. Heart

tissue biopsies in patients with various heart diseases showed a

Coenzyme Q10 deficiency in 50 to 75 percent of the cases. Being one

of the most metabolically active tissues in the body, the heart may

be unusually susceptible to the effects of Co-Q-10 deficiency.

In one study, twelve patients with stable angina pectoris were

treated with Co-Q-10 (150 mg per day for four weeks) in a double-

blind. crossover trial. Compared to the placebo, Co-Q-10 reduced the

frequency of anginal attacks by 53%! In addition, there was a

significant increase in treadmill exercise tolerance (time to onset

of chest pain and time to development of electrocardiogram

abnormalities) during the Co-Q-10 treatment. The results of this

study and many others suggest that Co-Q-10 is a safe and effective

treatment for angina pectoris.

DEPRESSED IMMUNE SYSTEM

* Cancer * Chronic Fatigue Syndrome * Periodontal Disease * Aging

Scientific evidence suggests that nutrition can play a role in cancer

prevention. But no diet has been shown to reverse cancer - and no

diet cures cancer. Vitamins, minerals, and other nutrients may

inhibit cancer by neutralizing carcinogens, ensuring proper immune

system function, or preventing tissue and cell damage. Researchers

are particularly interested in antioxidants which have been found

effective in minimizing immune system depression and cell damage. The

use and effectiveness of antioxidant supplements such as Co-Q-10,

Vitamin E, Vitamin C, Vitamin A, Selenium, Folic Acid and others, are

currently being studied.

Co-Q-10 and Vitamin B12 are nutritional supplements that may lessen

the symptoms normally associated with chronic fatigue syndrome (CFS).

This is primarily due to their proven antioxidant and immune system

supporting properties.

Coenzyme Q10 exerts its protective and strengthening action in all

tissues. Working from the cellular level, it strengthens the gums as

well as the heart muscle. Many scientists believe that periodontal

(gum) disease is a good indicator of low levels of Co-Q-10 in other

tissues. The American Dental Association states that at least 87% of

the American population has some sort of gum disease. This has been

shown to be somewhat related to nutrition and particularly to levels

of Co-Q-10, which has been shown to have a good protective effect for

gum tissue.

In addition, the elderly in general may have increased Co-Q-10

requirements as the decline of Co-Q-10 levels that occurs with age

may be partly responsible for age-related deterioration of the immune

system.

ACQUIRED IMMUNE DEFICIENCY SYNDROME

One of the most remarkable findings has been that Co-Q-10

supplementation could extend the lifespan of patients with acquired

immune deficiency syndrome or AIDS. In 1986, Drs. Folkers and

Langsjoen began treating seven patients with HIV or AIDS. Not all of

the patients consistently took Co-Q-10, but the treatment was very

encouraging and at times even striking. Folkers writes in Biochemical

and Biophysical Research Communications:

" All seven patients (three AIDS, four ARC) felt better soon after

starting on Co-Q-10, " writes Folkers. " The three who continued taking

Co-Q-10 remain alive and well in 1995. " It's with the treatment of

AIDS that the medical story of Co-Q-10 turns into one of economic

intrigue. The University of Texas, where the AIDS / Co-Q-10 research

was conducted, applied for a " use-patent " for the treatment of AIDS.

The patent (#1,011,858), one of several for Co-Q-10 and immune

function, was granted on April 30, 1991. The use-patent gives the

owner full patent rights to the nutrient, when it's prescribed for

the treatment of AIDS.

In 1993, the university sold the use patent to , an

investment banker and one of the patients in Folkers' original

cardiomyopathy study. , head of Pharmaceuticals (which has

no employees and does no research) paid several hundred thousand

dollars for the use-patent, then quickly sold it for an estimated $2

million to Receptagen, a U.S. / Canadian biotechnology firm. The

company plans to market prescription versions of Co-Q-10 for the

treatment of AIDS sometime in the future.

OBESITY

It has been shown at the University of Texas and the University of

Antwerp, Belgium that obese people can lose weight by simply

including significant amounts of Coenzyme Q10 to their diet. This

research showed that obese people can have as much as a 50%

deficiency of Co-Q-10 in their tissues.

People who eat a lot and yet stay slim have significantly higher

levels of Co-Q-10 in their blood. This wonderful coenzyme can

increase metabolic fuel efficiency within your cells thus stimulating

natural weight loss.

SUGGESTED DOSAGES AND AVAILABILITY

The amount of Coenzyme Q10 present in the body declines with age, so

it should be supplemented in the diet, especially by people who are

over the age of 40. There is no definite dosage determined, but

remember that more is needed as more energy is required. This is

especially so if extra nutritional support is needed for the vital

systems of the body that utilize Co-Q-10.

Therapeutic dosages of Co-Q-10 for serious diseases range from 200 mg

to 400 mg daily, ideally under a physician's supervision. A common

preventive dose ranges from 30 mg to 100 mg daily.

Although Co-Q-10 is found in many foods, only organ meats contain

significant amounts. Unfortunately, most people do not eat these

foods, hence the need for supplementation. Specific sources of Co-Q-

10 include mackerel, salmon, beef, peanuts, and spinach.

Please note: the information contained herein has been compiled from

various sources. The above statements have not been evaluated by the

U.S. Food and Drug Administration. We make no claims, either

expressed or implied, that any products mentioned in this newsletter

will cure disease, replace prescription medication, or supersede

sound medical advice.

Information compiled by

Jeff el